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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorGARNICA, Marcia
dc.contributor.authorPIERROTTI, Ligia Camera
dc.contributor.authorOLIVEIRA, Paula Vanessa de
dc.contributor.authorMAZZI, Mariana
dc.contributor.authorCHEBABO, Alberto
dc.date.accessioned2021-06-17T13:57:49Z-
dc.date.available2021-06-17T13:57:49Z-
dc.date.issued2021
dc.identifier.citationBRAZILIAN JOURNAL OF INFECTIOUS DISEASES, v.25, n.2, article ID 101548, 4p, 2021
dc.identifier.issn1413-8670
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/40972-
dc.description.abstractThis report shows the contribution of next-generation metagenomic sequencing (mNGS) as an alternative to challenging diagnostic infection in immunosuppressed individuals. Herein, we report three acute leukemia patients who developed severe invasive infections due to different etiologies: fungi, viruses, and protozoa. mNGS improved the diagnosis of the infections and provided the opportunity for adequate therapy. The mNGS is a hypothesis-free diagnostic platform, increasing potential in challenging diseases in hematological patients due to the extended diagnostic panel and the expedite access to the result. (C) 2021 Sociedade Brasileira de Infectologia.eng
dc.language.isoeng
dc.publisherELSEVIER BRAZILeng
dc.relation.ispartofBrazilian Journal of Infectious Diseases
dc.rightsopenAccesseng
dc.subjectMetagenomicseng
dc.subjectDiagnosiseng
dc.subjectInfectioneng
dc.subjectCancereng
dc.subjectLeukemiaeng
dc.subject.otherhepatosplenic candidiasiseng
dc.titleMetagenomic next-generation sequencing (mNGS) for diagnostically challenging infectious diseases in patients with acute leukemiaeng
dc.typearticleeng
dc.rights.holderCopyright ELSEVIER BRAZILeng
dc.identifier.doi10.1016/j.bjid.2021.101548
dc.identifier.pmid33639095
dc.subject.wosInfectious Diseaseseng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
hcfmusp.author.externalGARNICA, Marcia:Univ Fed Rio de Janeiro, Rio De Janeiro, RJ, Brazil; Complex Hosp Niteroi, Niteroi, RJ, Brazil
hcfmusp.author.externalOLIVEIRA, Paula Vanessa de:Complex Hosp Niteroi, Niteroi, RJ, Brazil
hcfmusp.author.externalMAZZI, Mariana:Complex Hosp Niteroi, Niteroi, RJ, Brazil
hcfmusp.author.externalCHEBABO, Alberto:Univ Fed Rio de Janeiro, Rio De Janeiro, RJ, Brazil; Lab Dasa, Sao Paulo, SP, Brazil
hcfmusp.description.articlenumber101548
hcfmusp.description.issue2
hcfmusp.description.volume25
hcfmusp.origemWOS
hcfmusp.origem.idWOS:000648910300005
hcfmusp.origem.id2-s2.0-85101782854
hcfmusp.origem.idSCIELO:S1413-86702021000200400
hcfmusp.publisher.cityRIO DE JANEIROeng
hcfmusp.publisher.countryBRAZILeng
hcfmusp.relation.referenceAlbert E, 2017, J CLIN VIROL, V94, P22, DOI 10.1016/j.jcv.2017.07.001eng
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hcfmusp.relation.referenceHoriba K, 2018, SCI REP-UK, V8, DOI 10.1038/s41598-018-22133-yeng
hcfmusp.relation.referenceHoward DS, 1999, CLIN INFECT DIS, V29, P1494, DOI 10.1086/313514eng
hcfmusp.relation.referenceKontoyiannis DP, 2000, INFECT DIS CLIN N AM, V14, P721, DOI 10.1016/S0891-5520(05)70128-8eng
hcfmusp.relation.referencePaccoud O, 2020, BONE MARROW TRANSPL, V55, DOI 10.1038/s41409-019-0641-yeng
hcfmusp.relation.referencePrestes DP, 2018, BONE MARROW TRANSPL, V53, P1336, DOI 10.1038/s41409-018-0179-4eng
hcfmusp.relation.referenceSimner PJ, 2018, CLIN INFECT DIS, V66, P778, DOI 10.1093/cid/cix881eng
hcfmusp.relation.referencevan Prehn J, 2017, ONCOLOGIST, V22, P989, DOI 10.1634/theoncologist.2017-0019eng
dc.description.indexMEDLINEeng
dc.identifier.eissn1678-4391
hcfmusp.citation.scopus6-
hcfmusp.scopus.lastupdate2024-03-29-
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Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/47
LIM/47 - Laboratório de Hepatologia por Vírus

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


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