Glaucoma, but not cataracts, predicts lower verbal fluency performance: 3.8-year follow-up from the ELSA-Brasil study

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Tipo de produção
article
Data de publicação
2021
Título da Revista
ISSN da Revista
Título do Volume
Editora
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
Autores
MORENO, Arlinda B.
DUNCAN, Bruce
SCHMIDT, Maria Ines
MAESTRI, Marcelo
BARRETO, Sandhi M.
Citação
AGING NEUROPSYCHOLOGY AND COGNITION, v.28, n.6, p.871-883, 2021
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Glaucoma, cataracts, and cognitive decline are most common in older ages. Although cross-sectional studies showed that these disorders are associated, follow-up studies are lacking. To investigate this issue, baseline and follow-up data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) were employed. We evaluated participants >= 55 years-old at follow-up without diagnosis of dementia, stroke, and other eye conditions except for glaucoma and cataracts. Cognition was evaluated using delayed word recall, verbal fluency, and trail making (version B) tests. Regression models were employed to investigate associations between glaucoma and cognition, adjusted by several confounders. Out of 3,867 participants, 379 and 118 presented cataracts and glaucoma, respectively. Only glaucoma was apredictor of lower verbal fluency (B = -0.23, 95% CI -035 to -012, p< 0.001). Other associations were not significant (ps>0.57). Our results suggest that glaucoma may be related to declining cognition.
Palavras-chave
Cohort study, verbal fluency, glaucoma, cataracts, cognition, eye diseases
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