Microbiology of Diabetic Foot Infections in a Tertiary Care Hospital in Sao Paulo, Brazil
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Citações na Scopus
3
Tipo de produção
article
Data de publicação
2022
Título da Revista
ISSN da Revista
Título do Volume
Editora
MDPI
Autores
PALOMO, Amanda Thurler
PIRES, Ana Paula Maia
MATIELO, Marcelo Fernando
SOARES, Rafael de Athayde
PECEGO, Christiano
SACILOTTO, Roberto
PAULA, Alexandre Inacio de
HOSINO, Nair
GAMBA, Cristiano de Melo
FONSECA, Cibele Lefreve
Citação
ANTIBIOTICS-BASEL, v.11, n.8, article ID 1125, 8p, 2022
Resumo
Diabetic foot infections (DFIs) are one of the causes of hospitalization in diabetic patients and, when this occurs, empirical antibiotic therapy is necessary. We have conducted a retrospective study of patients with DFI that required hospitalization to evaluate microbiologic profile and the susceptibility pattern of these infections. We evaluated 320 patients, of which 223 (69.7%) were male with a media age of 71 years with 276 isolates. Gram-positive bacteria were responsible for 188 (68.1%) of the isolates, while Gram-negative bacilli were responsible for 88 (31.9%). E. faecalis was the most prevalent pathogen, followed by S. aureus and coagulase negative Staphylococci. Among Gram-negative pathogens, P. aeruginosa was the most prevalent agent. Regarding the susceptibility profile, we found ampicillin-sensitive enterococci in 89% of the cases, oxacillin-sensitive S. aureus in 47%, but in coagulase-negative staphylococci, oxacillin was sensible only in 20%. The susceptibility profile of Gram-negatives was very good with 76% susceptibility of P. aeruginosa to ceftazidime and meropenem. The other prevalent Enterobacterales had great susceptibility to ceftazidime, piperacillin-tazobactam and 100% susceptibility to meropenem, with the exception of K. pneumoniae, which had 75% susceptibility to meropenem. Knowledge of microbiological profile and susceptibility patterns of patients with DFIs is useful to guide empirical therapy.
Palavras-chave
diabetic foot infections, microbiology, epidemiology
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