Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil

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art_PETERLE_Osteoporotic_hip_fractureComorbidities_and_factors_associated_with_inhospital_.PDF (861.86 KB)
Citações na Scopus
4
Tipo de produção
article
Data de publicação
2022
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
PUBLIC LIBRARY SCIENCE
Autores
PETERLE, Viviane Cristina Uliana
NOVAES, Maria Rita Carvalho Garbi
BEZERRA JUNIOR, Paulo Emiliano
CAVALCANTE, Rodrigo Tinoco Magalhaes
SILVA JUNIOR, Jurandi Barrozo da
PORTELA, Ray Costa
PAULA, Ana Patricia de
Citação
PLOS ONE, v.17, n.8, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
IntroductionThe aim of the study was to identify factors associated with the causes of in-hospital morbidity and mortality in an elderly Brazilian population due to osteoporotic hip fractures. MethodRetrospective cohort study involving a population over 60 years of age admitted to hospital due to osteoporotic hip fractures and followed up from hospitalization to outcome (discharge or mortality) from 2010 to 2018, in a public hospital in Brasilia, the capital of Brazil. Multivariate analysis was performed using the Poisson regression model with a robust variance, observing the hierarchical model proposed and the receiver operating characteristic (ROC) curve to obtain the cutoff point for mortality incidence in relation the total length of hospital stay. Significance level was set as p < 0.05. The analyses were conducted using the SAS 9.4 software. ResultThe mean hospital mortality rate among the 402 patients involved was 18.4%, and the associations made with the outcome mortality were per relevance: respiratory infection, age over 90 years, high preoperative cardiovascular risk, chronic obstructive pulmonary disease (COPD) as comorbidity, serum hemoglobin level <= 10 and other infections. Mortality also showed association with longer total length of hospital stay, as well as with prolonged postoperative period. ConclusionHip fractures in the elderly due to osteoporosis indicate a relationship between the sicker profile of the aging elderly population and the prevalence of chronic diseases strongly associated with in-hospital infections, contributing to increased mortality. There were fewer early interventions, and mortality was also associated with prolonged postoperative period. The aim of this study was not to compare independent variables with each other, but suggests the relationship between the presence of comorbidities, which predisposes to the development of infections, directly linked to mortality.
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URI
https://observatorio.fm.usp.br/handle/OPI/53225
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Coleções
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/ICHC