Endovascular treatment of mycotic aneurysms: An update meta-analysis
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article
Data de publicação
2024
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ELSEVIER
Autores
BATISTA, Savio
OLIVEIRA, Leonardo de Barros
FILHO, Jose Alberto Almeida
ABREU, Livia Viviani
ANDREAO, Filipi Fim
PALAVANI, Lucca B.
FILHO, Cesar A. F. Alves
BRAGA, Fausto de Oliveira
MACHADO, Elias A. T.
Citação
CLINICAL NEUROLOGY AND NEUROSURGERY, v.236, article ID 108068, 9p, 2024
Resumo
Introduction: Intracranial mycotic or infectious aneurysms result from the infection of arterial walls, most caused by bacterial or fungal organisms. These infections can weaken the arterial wall, leading to the formation of an aneurysm, a localized dilation, or a bulge. The management can be conservative mainly based on antibiotics or invasive methods such as clipping or endovascular treatment. Purpose: We performed a systematic review and meta-analysis of the current literature on endovascular treatment of mycotic aneurysms, analyzing the safety and efficacy associated with this procedure. Methods: We systematically searched on PUBMED, Cochrane Library, Embase, and Web of Science databases. Our search strategy was carefully crafted to conduct a thorough investigation of the topic, utilizing a comprehensive combination of relevant keywords. This meta-analysis included all studies that reported endovascular treatment of mycotic aneurysms. To minimize the risk of bias, studies with fewer than four patients, studies where the main outcome was not found, and studies with no clear differentiation between microsurgical and endovascular treatment were excluded. Results: In a comprehensive analysis of 134 patients, it was observed that all except one patient received anti-biotics as part of their treatment. Among the patients, 56% (a total of 51 out of 90 patients) underwent cardiac surgery. Additionally, three patients required a craniotomy following endovascular treatment. 12 patients experienced morbidity related to the procedures performed, indicating complications arising from the in-terventions. Furthermore, four aneurysms experienced rebleeding while treatment. A pooled analysis of the endovascular treatment of the mycotic aneurysm revealed a good level of technical success, achieving a 100% success rate in 12 out of 14 studies (97-100%; CI 95%; I2 = 0%), as illustrated in Fig. 2. Similarly, the aneurysm occlusion rate demonstrated a notable efficacy, with a success rate of 97% observed in 12 out of 14 studies (97-100%; CI 95%; I2 = 0%), as depicted in Fig. 3.Conclusion: The results strongly support the efficacy of endovascular treatment in achieving technical success, complete aneurysm occlusion, and favorable neurological outcomes. Additionally, the notably low incidence of complications and procedure-related mortality reaffirms the safety and benefits associated with this intervention.
Palavras-chave
Mycotic Aneurysm, Infectious Aneurysm, Endovascular Treatment
Referências
- Abdalkader M, 2023, WORLD NEUROSURG, V170, P238, DOI 10.1016/j.wneu.2022.11.035
- Ahmed AZ, 2015, EGYPT J RADIOL NUC M, V46, P117, DOI 10.1016/j.ejrnm.2014.12.001
- Allen LM, 2013, AM J NEURORADIOL, V34, P823, DOI 10.3174/ajnr.A3302
- BOHMFALK GL, 1978, J NEUROSURG, V48, P369, DOI 10.3171/jns.1978.48.3.0369
- Chalouhi N, 2013, CLIN NEUROL NEUROSUR, V115, P2528, DOI 10.1016/j.clineuro.2013.10.018
- Chapot R, 2002, RADIOLOGY, V222, P389, DOI 10.1148/radiol.2222010432
- Cheng-Ching E, 2017, INTERV NEUROL, V6, P82, DOI 10.1159/000455806
- Chun JY, 2001, NEUROSURGERY, V48, P1203, DOI 10.1097/00006123-200106000-00001
- Dhomne S, 2008, BRIT J NEUROSURG, V22, P46, DOI 10.1080/02688690701593561
- Ducruet AF, 2010, NEUROSURG REV, V33, P37, DOI 10.1007/s10143-009-0233-1
- Esenkaya A, 2016, NEURORADIOLOGY, V58, P277, DOI 10.1007/s00234-015-1633-2
- Grandhi R, 2014, J NEUROINTERV SURG, V6, P353, DOI 10.1136/neurintsurg-2013-010755
- Ihn YK, 2018, INTERV NEURORADIOL, V24, P237, DOI 10.1177/1591019918758493
- Jadhav AP, 2013, J NEUROINTERV SURG, V5, P562, DOI 10.1136/neurintsurg-2012-010460
- Kannoth S, 2009, NEUROCRIT CARE, V11, P120, DOI 10.1007/s12028-009-9208-x
- Kashkoush A, 2023, OPER NEUROSURG, V24, P492, DOI 10.1227/ons.0000000000000593
- Khan Aleena, 2017, Surg Neurol Int, V8, P144, DOI 10.4103/sni.sni_78_17
- Kiwan Ruba, 2022, Surg Neurol Int, V13, P185, DOI 10.25259/SNI_69_2022
- Kuo I, 2010, CASE REP MED, V2010, DOI 10.1155/2010/168408
- Laohapensang Kamphol, 2010, Ann Vasc Dis, V3, P16, DOI 10.3400/avd.AVDctiia09002
- Majeed H., 2023, StatPearls
- Matsubara N, 2015, NEUROL MED-CHIR, V55, P155, DOI 10.2176/nmc.oa.2014-0197
- McCready RA, 2006, ANN VASC SURG, V20, P590, DOI 10.1007/s10016-006-9107-y
- Nonaka S, 2016, J STROKE CEREBROVASC, V25, pE33, DOI 10.1016/j.jstrokecerebrovasdis.2015.11.033
- Page MJ, 2022, REV PANAM SALUD PUBL, V46, DOI [10.1186/s13643-021-01626-4, 10.26633/RPSP.2022.112, 10.1371/journal.pmed.1003583, 10.1016/j.rec.2021.07.010, 10.1016/j.jclinepi.2021.03.001, 10.1016/j.ijsu.2021.105906, 10.1136/bmj.n71]
- Park W, 2017, WORLD NEUROSURG, V97, P351, DOI 10.1016/j.wneu.2016.09.119
- Petr O, 2016, J NEURORADIOLOGY, V43, P309, DOI 10.1016/j.neurad.2016.03.008
- Ragulojan R, 2019, J STROKE CEREBROVASC, V28, P838, DOI 10.1016/j.jstrokecerebrovasdis.2018.11.035
- Ryttlefors M, 2008, STROKE, V39, P2720, DOI 10.1161/STROKEAHA.107.506030
- Serrano F, 2022, NEURORADIOLOGY, V64, P353, DOI 10.1007/s00234-021-02798-5
- Singla A, 2016, J NEUROINTERV SURG, V8, DOI 10.1136/neurintsurg-2015-011834
- Sörelius K, 2017, J CARDIOVASC SURG, V58, P870, DOI 10.23736/S0021-9509.17.10069-8
- TUCKSON W, 1985, J NATL MED ASSOC, V77, P99
- Wajnberg E, 2008, ARQ NEURO-PSIQUIAT, V66, P790, DOI 10.1590/S0004-282X2008000600002
- WFITN2022_Program, 2022, Interventional Neuroradiology, V28, P17, DOI [10.1177/15910199221142492cre, DOI 10.1177/15910199221142492CRE]
- Zanaty M, 2013, BIOMED RES INT, V2013, DOI 10.1155/2013/151643