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Title: | Assessment of a Neurophysiological Model of the Mandibular Branch of the Facial Nerve in Rats by Electromyography |
Authors: | SALOMONE, Raquel; COSTA, Heloisa Juliana Zabeu Rossi; RODRIGUES, Jose Ricardo Ferreira; SILVA, Samanta Marques Reis e; ORANDO, Patricia Camacho; BENTO, Ricardo Ferreira |
Citation: | ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, v.121, n.3, p.179-184, 2012 |
Abstract: | Objectives: Our objective was to develop an experimental model for the noninvasive and objective evaluation of facial nerve regeneration in rats using a motor nerve conduction test (electromyography). Methods: Twenty-two rats were submitted to neurophysiological evaluation using motor nerve conduction of the mandibular branch of the facial nerve to obtain the compound muscle action potentials (CMAPs). To record the CM APs, we used two needle electrodes that were inserted into the lower lip muscle of the rat. A supramaximal electrical stimulus was applied, and the values of CMAP latency, amplitude, length, area, and stimulus intensity obtained from each side were compared by use of the Wilcoxon test. Results: There was no significant difference (all p > 0.05) in latency, amplitude, duration, area, or intensity of stimuli between the two sides. The amplitudes ranged between 1.61 and 8.30 mV, the latencies between 1.03 and 1.97 ms, and the stimulus intensities between 1.50 and 2.90 mA. Conclusions: This is a noninvasive, easy, and highly reproducible method that contributes to an improvement of the techniques previously described and may contribute to future studies of the degeneration and regeneration of the facial nerve. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MOF Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/32 |
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