CAROLINE NUNES ROCHA MUNIZ
Projetos de Pesquisa
Unidades Organizacionais
FMUSP, Hospital das Clínicas, Faculdade de Medicina
LIM/34 - Laboratório de Ciências da Reabilitação, Hospital das Clínicas, Faculdade de Medicina
LIM/34 - Laboratório de Ciências da Reabilitação, Hospital das Clínicas, Faculdade de Medicina
11 resultados
Resultados de Busca
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- The influence of oral language environment on auditory development(2020) MONTEIRO, Thais Regina; ROCHA-MUNIZ, Caroline Nunes; FILIPPINI, Renata; MORAIS, Aline Albuquerque; SCHOCHAT, ElianeObjective: The purpose of this study was to compare the auditory processing of hearing children who were immersed in an oral language environment during early childhood with that of children who were poorly exposed to oral language during the same period. Methods: Sixty children aged between 5 and 10 years participated in this study. They were divided in two groups. Group 1 comprised of 30 children who had deaf signer parents, and Group 2 comprised of 30 children who had hearing parents. These children underwent the following auditory processing tests: Pediatric Speech Intelligibility, Dichotic Digits, Pitch Pattern Sequence, Gaps-in-Noise, and Memory Tests for Instrumental and Verbal sounds. Results: Group 1 had significantly poorer performance than that of Group 2 in all tests. In addition, an analysis by age range revealed that the differences between groups were more pronounced in younger children (5-6 years). Conclusion: The results indicate that the development of auditory skills is strongly influenced by access to oral linguistic sounds. Thus, a child's exposure to an oral language environment from birth is important to the adequate development of the auditory system functions.
- Medial olivocochlear function in children with poor speech-in-noise performance and language disorder(2017) ROCHA-MUNIZ, Caroline Nunes; CARVALLO, Renata Mota Mamede; SCHOCHAT, ElianeObjectives: Contralateral masking of transient-evoked otoacoustic emissions is a phenomenon that suggests an inhibitory effect of the olivocochlear efferent auditory pathway. Many studies have been inconclusive in demonstrating a clear connection between this system and a behavioral speech-in-noise listening skill. The purpose of this study was to investigate the activation of a medial olivocochlear (MOC) efferent in children with poor speech-in-noise (PSIN) performance and children with language impairment and PSIN (SLI + PSIN). Methods: Transient evoked otoacoustic emissions (TEOAEs) with and without contralateral white noise were tested in 52 children (between 6 and 12 years). These children were arranged in three groups: typical development (TD) (n = 25), PSIN (n = 14) and SLI + PSI (n = 13). Results: PSIN and SLI + PSI groups presented reduced otoacoustic emission suppression in comparison with the TD group. Conclusion: Our finding suggests differences in MOC function among children with typical development and children with poor SIN and language problems.
- Auditory temporal resolution and backward masking in musicians with absolute pitch(2023) LEITE FILHO, Carlos Alberto; ROCHA-MUNIZ, Caroline Nunes; PEREIRA, Liliane Desgualdo; SCHOCHAT, ElianeAmong the many questions regarding the ability to effortlessly name musical notes without a reference, also known as absolute pitch, the neural processes by which this phenomenon operates are still a matter of debate. Although a perceptual subprocess is currently accepted by the literature, the participation of some aspects of auditory processing still needs to be determined. We conducted two experiments to investigate the relationship between absolute pitch and two aspects of auditory temporal processing, namely temporal resolution and backward masking. In the first experiment, musicians were organized into two groups according to the presence of absolute pitch, as determined by a pitch identification test, and compared regarding their performance in the Gaps-in-Noise test, a gap detection task for assessing temporal resolution. Despite the lack of statistically significant difference between the groups, the Gaps-in-Noise test measures were significant predictors of the measures for pitch naming precision, even after controlling for possible confounding variables. In the second experiment, another two groups of musicians with and without absolute pitch were submitted to the backward masking test, with no difference between the groups and no correlation between backward masking and absolute pitch measures. The results from both experiments suggest that only part of temporal processing is involved in absolute pitch, indicating that not all aspects of auditory perception are related to the perceptual subprocess. Possible explanations for these findings include the notable overlap of brain areas involved in both temporal resolution and absolute pitch, which is not present in the case of backward masking, and the relevance of temporal resolution to analyze the temporal fine structure of sound in pitch perception.
- Investigation of the neural discrimination of acoustic characteristics of speech sounds in normal-hearing individuals through Frequency-following Response (FFR)(2021) ROCHA-MUNIZ, Caroline Nunes; SCHOCHAT, ElianePurpose: To evaluate how the auditory pathways encode and discriminate the plosive syllables [ga], [da] and [ba] using the auditory evoked Frequency-following Response (FFR) in children with typical development. Methods: Twenty children aged 6-12 years were evaluated using the FFR for the [ga], [da] and [ba] stimuli. The stimuli were composed of six formants and were differentiated in the F2 to F3 transition (transient portion). The other formants were identical in the three syllables (sustained portion). The latencies of the 16 waves of the transient portion (<70ms) and of the 21 waves of the sustained portion (90-160ms) of the stimuli were analyzed in the neural responses obtained for each of the syllables. Results: The transient portion latencies were different in the three syllables, indicating a distinction in the acoustic characteristics of these syllables through their neural representations. In addition, the transient portion latencies progressively increased in the following order: [ga] <[da] <[ba], whereas no significant differences were observed in the sustained portion. Conclusion: The FFR proved to be an efficient tool to investigate the subcortical acoustic differences in speech sounds, since it demonstrated different electrophysiological responses for the three evoked syllables. Changes in latency were observed in the transient portion (consonants) but not in the sustained portion (vowels) for the three stimuli. These results indicate the neural ability to distinguish between acoustic characteristics of the [ga], [da] and [ba] stimuli.
- Efficacy of auditory training in elderly subjects(2015) MORAIS, Aline Albuquerque; ROCHA-MUNIZ, Caroline Nunes; SCHOCHAT, ElianeAuditory training (AT) has been used for auditory rehabilitation in elderly individuals and is an effective tool for optimizing speech processing in this population. However, it is necessary to distinguish training-related improvements from placebo and test-retest effects. Thus, we investigated the efficacy of short-term AT [acoustically controlled auditory training (ACAT)] in elderly subjects through behavioral measures and P300. Sixteen elderly individuals with auditory processing disorder (APD) received an initial evaluation (evaluation 1 E1) consisting of behavioral and electrophysiological tests (P300 evoked by tone burst and speech sounds) to evaluate their auditory processing. The individuals were divided into two groups. The Active Control Group (n = 8) underwent placebo training. The Passive Control Group (n = 8) did not receive any intervention. After 12 weeks, the subjects were revaluated (evaluation 2 - E2). Then, all of the subjects underwent ACAT. Following another 12 weeks (eight training sessions), they underwent the final evaluation (evaluation 3 - E3). There was no significant difference between E1 and E2 in the behavioral test [F(9.6) = 0.06, p = 0.92, lambda de Wilks = 0.65)] or P300 [F(8.7) = 2.11, p = 0.17, lambda de Wilks = 0.29] (discarding the presence of placebo effects and test-retest). A significant improvement was observed between the pre- and post-ACAT conditions (E2 and E3) for all auditory skills according to the behavioral methods [F(4.27) = 0.18, p = 0.94, lambda de Wilks = 0.97]. However, the same result was not observed for P300 in any condition. There was no significant difference between P300 stimuli. The ACAT improved the behavioral performance of the elderly for all auditory skills and was an effective method for hearing rehabilitation.
- Ongoing maturation in the time-compressed speech test(2018) RABELO, Camila Maia; ROCHA-MUNIZ, Caroline Nunes; SCHOCHAT, ElianeOBJECTIVES: To verify the neuromaturational influence in the ability of auditory closure, that is, to verify the performance of children and young adults in the ability of auditory closure, through the time compressed speech test (TCS). METHODS: Thirty children (8 to 10 years old) and 30 young adults (16 to 24 years old) with normal hearing without complaints (neurological, cognitive, auditory processing) who performed TFC (monosyllables and disyllables) with a compression ratio of 60% in both ears. Statistical analysis was performed using analysis of variance (ANOVA) and ANOVA with repeated measures with a significance level of 0.05. The minimum statistical power was 80%. RESULTS: In the comparison between ears, there was no significant difference between groups for the monosyllables. For disyllables, the second ear tested was better in children, and the right ear was better than the left ear for young adults. In the comparison between modalities (monosyllables and disyllables), children did not show significant differences. The performance of the young adults was better in the disyllables in both ears. Comparing the age groups, the young adults were better than the children for both modalities and ears. CONCLUSION: The study has demonstrated the influence and impact of age (maturational factor) on TCS test performance, showing the importance of establishing normality patterns for various age groups to provide a standardized tool for evaluation of auditory closure ability.
- Association between language development and auditory processing disorders(2014) ROCHA-MUNIZ, Caroline Nunes; ZACHI, Elaine Cristina; TEIXEIRA, Rosani Aparecida Antunes; VENTURA, Dora Fix; BEFI-LOPES, Debora Maria; SCHOCHAT, ElianeIntroduction: It is crucial to understand the complex processing of acoustic stimuli along the auditory pathway;comprehension of this complex processing can facilitate our understanding of the processes that underlie normal and altered human communication. Aim: To investigate the performance and lateralization effects on auditory processing assessment in children with specific language impairment (SLI), relating these findings to those obtained in children with auditory processing disorder (APD) and typical development (TD). Material and methods: Prospective study. Seventy-five children, aged 6-12 years, were separated in three groups: 25 children with SLI, 25 children with APD, and 25 children with TD. All went through the following tests: speech-in-noise test, Dichotic Digit test and Pitch Pattern Sequencing test. Results: The effects of lateralization were observed only in the SLI group, with the left ear presenting much lower scores than those presented to the right ear. The inter-group analysis has shown that in all tests children from APD and SLI groups had significantly poorer performance compared to TD group. Moreover, SLI group presented worse results than APD group. Conclusion: This study has shown, in children with SLI, an inefficient processing of essential sound components and an effect of lateralization. These findings may indicate that neural processes (required for auditory processing) are different between auditory processing and speech disorders.
- Cortical inhibition effect in musicians and non-musicians using P300 with and without contralateral stimulation(2015) RABELO, Cannila Maia; NEVES-LOBO, Ivone Ferreira; ROCHA-MUNIZ, Caroline Nunes; UBIALI, Thalita; SCHOCHAT, ElianeIntroduction: Musicians have more robust and efficient neural responses in the cortical and sub-cortical regions, demonstrating that musical experience benefits the processing of both non-linguistic and linguistic stimuli. Objective: This study aimed to verify P300's latency and amplitude behavioral using contralateral stimulation in musicians and non-musicians. Methods: This was a case-control study. Subjects were divided in two groups: musicians, comprising 30 professional musicians, and non-musicians, comprising 25 subjects without musical experience. Results: The present study showed that the musicians had lower latencies and higher amplitudes than the non-musicians in the P300 without contralateral noise. For the P300 amplitude values, the difference between groups persisted, and the musicians presented significantly higher amplitude values compared with the non-musicians; additionally, the analysis of the noise effect on the P300 response showed that the latency values were significantly increased in the musicians. Conclusion: The central auditory nervous system of musicians presents peculiar characteristics of electrophysiological responses probably due to the plasticity imposed by musical practice.
- O Potencial Evocado Auditivo com estímulo de fala pode ser uma ferramenta útil na prática clínica?(2016) ROCHA-MUNIZ, Caroline Nunes; FILIPPINI, Renata; NEVES-LOBO, Ivone Ferreira; RABELO, Camila Maia; MORAIS, Aline Albuquerque; MURPHY, Cristina Ferraz Borges; CALARGA, Karenina Santos; LEITE, Libia Camargo Ribeiro; PIRES, Mayra Monteiro; SENA-YOSHINAGA, Taise Argolo; SCHOCHAT, ElianeABSTRACT Purpose : To discuss the clinical applicability of the speech-evoked Auditory Brainstem Response (speech-evoked ABR) to help identifying auditory processing disorders. Methods : We analyzed the records of 27 children and adolescents, aged between seven and 15, who presented abnormal speech-evoked ABR. Then, the data from the behavioral auditory processing evaluation of these individuals were surveyed. Results : It was observed that, among the 27 children with abnormal speech-evoked ABR, 23 also had auditory processing disorders. Therefore, from this sample, an 85.15% probability of observing abnormal behavioral assessment of auditory processing in a child who presented abnormal speech-evoked ABR was obtained. Conclusion : It is argued that the speech-evoked ABR can be used in clinical practice as an important aid tool in the diagnosis of auditory processing disorder, because, in this study, an abnormal speech-evoked ABR usually represented a deficit in the results of behavioral assessment of auditory processing. Thus, it can be used to obtain information about the perception of speech sounds in children under seven years or with challenging behavioral assessment.
- Sensitivity, specificity and efficiency of speech-evoked ABR(2014) ROCHA-MUNIZ, Caroline Nunes; BEFI-LOPES, Debora Maria; SCHOCHAT, ElianeWe determined the sensitivity, specificity and efficiency of speech-evoked Auditory Brainstem Response (ABR) as a diagnostic support for Auditory Processing Disorder (APD) and specific language impairment (SLI). Speech-evoked ABRs were elicited using the five-formant syllable/da/. The waveforms V. A. C, D, E, F. and 0 of all groups were analyzed. The sensitivity and specificity were calculated, and receiver operating characteristic analyses were performed to determine the optimum cut-off. Seventy-five children who were native speakers of Brazilian-Portuguese participated. The participants included 25 children with APD, 25 children with SLI and 25 with typical development. Statistical analysis demonstrated a cut-off for latency values of 6.48, 7.51, 17.82, 22.33, 30.79, 39.54 and 48.00 for V. A, C, D, E, F, and 0 waves, respectively. The A wave exhibited superior balance for the APD group. For the SLI group, the A, D and 0 waves exhibited the best balance. Furthermore, when analyzing the APD and SLI groups separately, better sensitivity values were observed for the SLI group than the APD group. Speech-evoked ABR is a useful test to identify auditory processing disorders and language impairment. Furthermore, this study represented an important step forward in establishing the clinical utility of speech-evoked ABR in Brazilian Portuguese-speaking children.