CARLOS HENRIQUE DEL CARLO
Índice h a partir de 2011
4
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
14 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 14
- Optimized Treatment and Heart Rate Reduction in Chronic Heart Failure(2013) MORENO, Irineu Blanco; CARLO, Carlos Henrique Del; PEREIRA-BARRETTO, Antonio CarlosBackground: Heart failure (HF) is a syndrome that leads to poor outcome in advanced forms. The neurohormonal blockade modifies this natural history; however, it is often suboptimal. Objective: The aim of this study is to assess at what percentage cardiologists used to treating HF can prescribe target doses of drugs of proven efficacy. Methods: A total of 104 outpatients with systolic dysfunction were consecutively enrolled, all under stabilized treatment. Demographic and treatment data were evaluated and the doses achieved were verified. The findings are shown as percentages and correlations are made between different variables. Results: The mean age of patients was 64.1 +/- 14.2 years, with SBP = 115.4 +/- 15.3, HR = 67.8 +/- 9.4 bpm, weight = 76.0 +/- 17.0 kg and sinus rhythm (90.4%). As for treatment, 93.3% received a RAS blocker (ACEI 52.9%), all received beta-blockers (BB), the most often prescribed being carvedilol (92.3%). As for the doses: 97.1% of those receiving an ARB were below the optimal dose and of those who received ACEI, 52.7% received an optimized dose. As for the BB, target doses were prescribed to 76.0% of them. In this group of patients, most with BB target dose, it can be seen that 36.5% had HR >= 70 bpm in sinus rhythm. Conclusion: Cardiologists used to treating HF can prescribe target doses of ACEI and BB to most patients. Even though they receive the recommended doses, about one third of patients persists with HR > 70 bpm and should have their treatment optimized.
conferenceObject Prognosis in advanced heart failure is related to betablocker doses(2013) BARRETTO, A. C. Pereira; MELO, D. S. B.; CARLO, C. H. Del; CARDOSO, J. N.; OCHIA, M. E.; MORGADO, P. C.; MUNHOZ, R. T.bookPart Miocardiopatias: Classificação, diagnóstico e etiologia(2017) CARDOSO, Juliano Novaes; CARLO, Carlos Henrique Del; BARRETTO, Antonio Carlos Pereira- Rule-out myocardial infarction in the high-sensitivity cardiac troponin era(2019) CARLO, Carlos H. Del
conferenceObject Mortality and predictors of death in women and men with congestive heart failure with preserved, mildly reduced, and reducedejection fraction(2022) BARRETTO, A.; CARLO, C. H. Del; RAMOS NETO, J. A.; ABREU, A. B.; SCIPIONI, A. R.; MANSUR, A. P.- Rare Association: Chagas' Disease and Hypertrophic Cardiomyopathy(2015) PASTORE, Carlos Alberto; SAMESIMA, Nelson; PEREIRA FILHO, Horacio Gomes; VARONI, Leonardo Paschoal Camacho; ROCHITTE, Carlos Eduardo; VIEIRA, Marcelo Luiz Campos; AVILA, Luiz Francisco Rodrigues de; MELO, Rodrigo de Jesus Louzeiro; PEREIRA, Alexandre da Costa; DAHEER, Julia; CARLO, Carlos Henrique delA woman (49 years) with Chagas' disease showed: ECG, right bundle-branch block and left anterior-superior fascicular block; V-1 has unusual R > R', and elevated ST segment from V-2 to V-6. Additional imaging revealed concomitant HCM and Chagas, which is uncommon. Overlapping of ECG findings can be explained by this rare association of diseases.
- Sex Differences in Heart Failure Mortality with Preserved, Mildly Reduced and Reduced Ejection Fraction: A Retrospective, Single-Center, Large-Cohort Study(2022) MANSUR, Antonio de Padua; CARLO, Carlo Henrique Del; GONCALINHO, Gustavo Henrique Ferreira; AVAKIAN, Solange Desiree; RIBEIRO, Lucas Carrara; IANNI, Barbara Maria; FERNANDES, Fabio; CESAR, Luiz Antonio Machado; BOCCHI, Edimar Alcides; PEREIRA-BARRETTO, Antonio CarlosBackground: Heart failure (HF) is one of the leading causes of death worldwide. Studies show that women have better survival rates than men despite higher hospitalizations. However, little is known about differences in mortality and predictors of death in women and men with HF with preserved (HFpEF), mildly reduced (HFmrEF), and reduced ejection fraction (HFrEF). Methods: From February 2017 to September 2020, mortality and predictors of death were analyzed in women and men with HF. Baseline data included clinical characteristics and echocardiographic findings. Results: A total of 11,282 patients, 63.9 +/- 14.4 years, including 6256 (55.4%) males, were studied. Females were older, had a higher baseline mean left ventricular ejection fraction (LVEF) and lower left ventricular diastolic diameter. During follow-ups, 1375 (22%) men and 925 (18.4%) women died. Cumulative incidence of death was higher in men with HFrEF but similar for HFmrEF and HFpEF. Cox regression for death showed renal dysfunction, stroke, diabetes, atrial fibrillation, age, LVEF, valve disease, MI, and hypertensive CMP as independent death predictors for all HF patients. Conclusions: Women had a better prognosis than men in HFrEF and similar mortality for HFmrEF and HFpEF, but sex was not an independent predictor of death for all HF subtypes.
- Variação Temporal no Prognóstico e Tratamento da Insuficiência Cardíaca Avançada - Antes e Após 2000(2014) CARLO, Carlos Henrique Del; CARDOSO, Juliano Novaes; OCHIA, Marcelo Eidi; OLIVEIRA JR., Mucio Tavares de; RAMIRES, José Antonio Franchini; PEREIRA-BARRETTO, Antonio CarlosBackground: The treatment of heart failure has evolved in recent decades suggesting that survival is increasing. Objective: To verify whether there has been improvement in the survival of patients with advanced heart failure. Methods: We retrospectively compared the treatment and follow-up data from two cohorts of patients with systolic heart failure admitted for compensation up to 2000 (n = 353) and after 2000 (n = 279). We analyzed in-hospital death, re-hospitalization and death in 1 year of follow-up. We used Mann-Whitney U test and chi-square test for comparison between groups. The predictors of mortality were identified by regression analysis through Cox proportional hazards model and survival analysis by the Kaplan-Meier survival analysis. Results: The patients admitted until 2000 were younger, had lower left ventricular impairment and received a lower proportion of beta-blockers at discharge. The survival of patients hospitalized before 2000 was lower than those hospitalized after 2000 (40.1% vs. 67.4%; p<0.001). The independent predictors of mortality in the regression analysis were: Chagas disease (hazard ratio: 1.9; 95% confidence interval: 1.3-3.0), angiotensin-converting-enzyme inhibitors (hazard ratio: 0.6; 95% confidence interval: 0.4-0.9), beta-blockers (hazard ratio: 0.3; 95% confidence interval: 0.2-0.5), creatinine ≥ 1.4 mg/dL (hazard ratio: 2.0; 95% confidence interval: 1.3-3.0), serum sodium ≤ 135 mEq/L (hazard ratio: 1.8; 95% confidence interval: 1.2-2.7). Conclusions: Patients with advanced heart failure showed a significant improvement in survival and reduction in re-hospitalizations. The neurohormonal blockade, with angiotensin-converting-enzyme inhibitors and beta-blockers, had an important role in increasing survival of these patients with advanced heart failure.
conferenceObject Prognosis of Congestive Heart Failure Due to Chagas Disease in Women and Men(2022) MANSUR, Antonio de Padua; CARLO, Carlos H. del; BOCCHI, Edimar A.; PEREIRA-BARRETTO, Antonio C.bookPart Miocardites, Pericardiopatias e Tumores do Coração(2016) CARLO, Carlos Henrique Del; BARRETO, Antonio Carlos Pereira