BRUNA MARIA THOMPSON JACINTO
Projetos de Pesquisa
Unidades Organizacionais
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia, Hospital das Clínicas, Faculdade de Medicina
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
bookPart Concordância anatomorradiológica, subestimação e acompanhemento(2017) JACINTO, Bruna Maria Thompson; GIANNOTTI, Marcelo Abrantes; TEIXEIRA, Patricia Akissue de Camargo; MATSUMOTO, Renato Augusto Eidy Kiota; FERREIRA, Vera Christina Camargo de SiqueirabookPart Aplicação do ACR BI-RADS® nos métodos de imagem em mama(2017) BARROS, Nestor de; DEBS, Cecília Lemos; CASTRO, Flávio Spinola; COSTENARO, Marco; JACINTO, Bruna Maria Trompson; TUCUNDUVA, Tatiana- Pre-treatment MRI tumor features and post-treatment mammographic findings: may they contribute to refining the prediction of pathologic complete response in post-neoadjuvant breast cancer patients with radiologic complete response on MRI?(2022) THOMPSON, Bruna M.; CHALA, Luciano F.; SHIMIZU, Carlos; MANO, Max S.; FILASSI, Jose R.; GEYER, Felipe C.; TORRES, Ulysses S.; MELLO, Giselle Guedes Netto de; LEITE, Claudia da CostaPurpose Radiologic complete response (rCR) in breast cancer patients after neoadjuvant chemotherapy (NAC) does not necessarily correlate with pathologic complete response (pCR), a marker traditionally associated with better outcomes. We sought to verify if data extracted from two important steps of the imaging workup (tumor features at pre-treatment MRI and post-treatment mammographic findings) might assist in refining the prediction of pCR in post-NAC patients showing rCR. Methods A total of 115 post-NAC women with rCR on MRI (2010-2016) were retrospectively assessed. Pre-treatment MRI (lesion morphology, size, and distribution) and post-treatment mammographic findings (calcification, asymmetry, mass, architectural distortion) were assessed, as well as clinical and molecular variables. Bivariate and multivariate analyses evaluated correlation between such variables and pCR. Post-NAC mammographic findings and their correlation with ductal in situ carcinoma (DCIS) were evaluated using Pearson's correlation. Results Tumor distribution at pre-treatment MRI was the only significant predictive imaging feature on multivariate analysis, with multicentric lesions having lower odds of pCR (p = 0.035). There was no significant association between tumor size and morphology with pCR. Mammographic residual calcifications were associated with DCIS (p = 0.009). The receptor subtype remained as a significant predictor, with HR-HER2 + and triple-negative status demonstrating higher odds of pCR on multivariate analyses. Conclusions Multicentric lesions on pre-NAC MRI were associated with a lower chance of pCR in post-NAC rCR patients. The receptor subtype remained a reliable predictor of pCR. Residual mammographic calcifications correlated with higher odds of malignancy, making the correlation between mammography and MRI essential for surgical planning.
bookPart Procedimentos percutâneos em mama orientados por métodos de imagem: biópsia e localização pré-operatória(2017) BARROS, Nestor de; CASTRO, Flávio Spinola; MORAES, Paula de Camargo; JACINTO, Bruna Maria Thompson; ICHIHARA, Tomie H.conferenceObject Does conservative surgery treatment for locally advanced breast cancer safe after neoadjuvant treatment?(2018) BOUFELLI, Gabriela; MOTA, Bruna Salani; FRANCA, Flavia Cardoso; DORIA, Maira Teixeira; MAESAKA, Jonathan Yugo; RICCI, Marcos Desiderio; PIATO, Jose Roberto Morales; ROCHA, Fernanda Barbosa Coelho; GIRIBELA, Aricia Helena Galvao; GONCALVES, Rodrigo; MASILI-OKU, Sergio; MANO, Max Senna; CHALA, Luciano Fernandes; THOMPSON, Bruna Maria; BARACAT, Edmund Chada; FILASSI, Jose Roberto- Encapsulated Papillary Breast Carcinoma: Anatomopathological and Clinicoradiological Aspects(2018) MATSUMOTO, R. A. E. K.; BRESCIANI, B. H.; THOMPSON, B. M.; BARROS, N. deEncapsulated papillary carcinoma or intracystic papillary carcinoma of the breast is a rare tumour and is a special subtype of carcinoma. The most relevant histological characteristic is the absence of a myoepithelial cell layer. The lack of such a layer leads to uncertainty in diagnosis and consequent management, depending on whether the tumour is considered an invasive neoplasm or an in-situ neoplasm. This article illustrates the histological characteristics of this subtype of breast cancer, its most common imaging presentation, clinical findings, diagnosis, and treatment.