Systematic review and meta-analysis of colon capsule endoscopy accuracy for colorectal cancer screening. An alternative during the Covid-19 pandemic?

Nenhuma Miniatura disponível
Citações na Scopus
7
Tipo de produção
article
Data de publicação
2022
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SAGE PUBLICATIONS LTD
Autores
Citação
JOURNAL OF MEDICAL SCREENING, v.29, n.3, p.148-155, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Aim To determine the diagnostic accuracy of colon capsule endoscopy for colorectal cancer screening. Methods Studies that compared the diagnostic performance of colonoscopy and second-generation colon capsule endoscopy (CCE-2) for screening of asymptomatic patients aged 50-75 years were included. The primary outcomes were sensitivity, specificity, and positive and negative likelihood ratios for polyps and adenomas measuring at least 6 mm or 10 mm. Results Eight full-text studies that evaluated 1602 patients were included for systematic review. Of these, 840 (52.43%) patients participated in an opportunistic screening program. The pooled outcomes of CCE-2 for polyps at least 6 mm / 10 mm were (CI = confidence interval): sensitivity: 88% (95% CI: 0.84-0.91) / 88% (95% CI: 0.82-0.93), specificity: 94% (95% CI: 0.92-0.95) / 95.5% (95% CI: 0.94-0.97); positive likelihood ratio: 11.86 (95% CI: 5.53-25.46) / 23.07 (95% CI: 6.163-86.36); negative likelihood ratio: 0.14 (95% CI: 0.1-0.21) / 0.14 (95% CI: 0.09-0.21). The area under the summary receiver operating characteristic curve for polyps at least 6 and 10 mm was 96.3% and 96.7%, respectively. The only cancer missed by complete CCE-2 was shown at multiple frames in the unblinded review. In total, 125 (7.8%) patients presented mild adverse events mostly related to bowel preparation. Conclusion CCE-2 is demonstrated to be an effective and safe alternative method for colorectal cancer screening. Diagnostic performance of CCE-2 for polyps of at least 6 and 10 mm was similar. Completion rates still need to be improved.
Palavras-chave
colon capsule, colorectal cancer, screening
URI
https://observatorio.fm.usp.br/handle/OPI/49216
Referências
  1. Adler SN, 2014, SURG ENDOSC, V28, P570, DOI 10.1007/s00464-013-3206-y
  2. Arnold M, 2020, GASTROENTEROLOGY, V159, P335, DOI 10.1053/j.gastro.2020.02.068
  3. Cadoni S, 2020, ENDOSC INT OPEN, V08, pE985, DOI 10.1055/a-1196-1711
  4. Cash BD, 2021, GUT, V70, P2115, DOI 10.1136/gutjnl-2020-322578
  5. Challine A, 2021, SURGERY, V169, P991, DOI 10.1016/j.surg.2020.12.021
  6. Chiu PWY, 2020, GUT, V69, P991, DOI 10.1136/gutjnl-2020-321185
  7. D'Ovidio V, 2021, CLIN COLORECTAL CANC, V20, pE5, DOI 10.1016/j.clcc.2020.07.006
  8. Eliakim R, 2009, ENDOSCOPY, V41, P1026, DOI 10.1055/s-0029-1215360
  9. Gonzalez-Suarez B, 2020, BMC MED, V18, DOI 10.1186/s12916-020-01717-4
  10. Gralnek IM, 2020, ENDOSCOPY, V52, P483, DOI 10.1055/a-1155-6229
  11. Heresbach D, 2008, ENDOSCOPY, V40, P284, DOI 10.1055/s-2007-995618
  12. Higgins JPT, 2002, STAT MED, V21, P1539, DOI 10.1002/sim.1186
  13. Holleran G, 2014, ENDOSCOPY, V46, P473, DOI 10.1055/s-0034-1365402
  14. de Jonge L, 2021, LANCET GASTROENTEROL, V6, P304, DOI 10.1016/S2468-1253(21)00003-0
  15. Kobaek-Larsen M, 2018, COLORECTAL DIS, V20, P479, DOI 10.1111/codi.13965
  16. Koulaouzidis G, 2022, GUT, V71, P440, DOI 10.1136/gutjnl-2021-324246
  17. Kudo SE, 1996, GASTROINTEST ENDOSC, V44, P8, DOI 10.1016/S0016-5107(96)70222-5
  18. Liao Z, 2021, ENDOSC INT OPEN, V09, pE280, DOI 10.1055/a-1333-6635
  19. MacLeod C, 2020, COLORECTAL DIS, V22, P621, DOI 10.1111/codi.15134
  20. Moher D, 2009, PLOS MED, V6, DOI 10.1371/journal.pmed.1000097
  21. Morris EJA, 2021, LANCET GASTROENTEROL, V6, P199, DOI 10.1016/S2468-1253(21)00005-4
  22. MOSES LE, 1993, STAT MED, V12, P1293, DOI 10.1002/sim.4780121203
  23. Pecere S, 2020, GASTROINTEST ENDOSC, V91, P406, DOI 10.1016/j.gie.2019.09.041
  24. Rex DK, 2015, GASTROENTEROLOGY, V148, P948, DOI 10.1053/j.gastro.2015.01.025
  25. Rondonotti E, 2014, CLIN GASTROENTEROL H, V12, P1303, DOI 10.1016/j.cgh.2013.12.027
  26. Saftoiu A, 2020, ENDOSCOPY, V52, P293, DOI 10.1055/a-1104-5245
  27. Satodate H, 2003, GASTROINTEST ENDOSC, V58, P288, DOI 10.1067/mge.2003.361
  28. Shaukat A, 2021, AM J GASTROENTEROL, V116, P458, DOI 10.14309/ajg.0000000000001122
  29. Shehadeh I, 2002, AM J GASTROENTEROL, V97, P1143
  30. Sieg A, 2011, WORLD J GASTRO ENDOS, V3, P81, DOI 10.4253/wjge.v3.i5.81
  31. Sieg A, 2009, AM J GASTROENTEROL, V104, P848, DOI 10.1038/ajg.2008.163
  32. Siegel RL, 2017, JAMA-J AM MED ASSOC, V318, P572, DOI 10.1001/jama.2017.7630
  33. Spada C, 2012, ENDOSCOPY, V44, P527, DOI 10.1055/s-0031-1291717
  34. Spada C, 2021, EUR RADIOL, V31, P2967, DOI [10.1007/s00330-020-07413-4, 10.1055/a-1258-4819]
  35. Spada C, 2011, GASTROINTEST ENDOSC, V74, P581, DOI 10.1016/j.gie.2011.03.1125
  36. Sulbaran M, 2018, ENDOSC INT OPEN, V6, pE531, DOI 10.1055/a-0577-2650
  37. Voska M, 2019, GASTROENT RES PRACT, V2019, DOI 10.1155/2019/5975438
  38. Whiting PF, 2011, ANN INTERN MED, V155, P529, DOI 10.7326/0003-4819-155-8-201110180-00009
  39. Yong KK, 2020, GUT, V69, P2267, DOI 10.1136/gutjnl-2020-321069

Coleções
Artigos e Materiais de Revistas Científicas - FM/MGT
Artigos e Materiais de Revistas Científicas - COVID-19
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/35
Artigos e Materiais de Revistas Científicas - LIM/47
Carregar mais