Microcephaly measurement in adults and its association with clinical variables
Carregando...
Citações na Scopus
1
Tipo de produção
article
Data de publicação
2022
Título da Revista
ISSN da Revista
Título do Volume
Editora
REVISTA DE SAUDE PUBLICA
Autores
MANCINE, Livia
SALVINI, Rogerio
TEIXEIRA, Juliana de Melo
Citação
REVISTA DE SAUDE PUBLICA, v.56, article ID 38, 10p, 2022
Resumo
OBJECTIVE: To establish a microcephaly cut-off size in adults using head circumference as an indirect measure of brain size, as well as to explore factors associated with microcephaly via data mining. METHODS: In autopsy studies, head circumference was measured with an inelastic tape placed around the skull. Total brain volume was also directly measured. A linear regression was used to determine the association of head circumference with brain volume and clinical variables. Microcephaly was defined as head circumference that were two standard deviations below the mean of significant clinical variables. We further applied an association rule mining to find rules associating microcephaly with several sociodemographic and clinical variables. RESULTS: In our sample of 2,508 adults, the mean head circumference was 55.3 +/- 2.7cm. Head circumference was related to height, cerebral volume, and sex (p < 0.001 for all). Microcephaly was present in 4.7% of the sample (n = 119). Out of 34,355 association rules, we found significant relationships between microcephaly and a clinical dementia rating (CDR) > 0.5 with an informant questionnaire on cognitive decline in the elderly (IQCODE) = 3.4 (confidence: 100% and lift: 5.6), between microcephaly and a CDR > 0.5 with age over 70 years (confidence: 42% and lift: 2.4), and microcephaly and males (confidence: 68.1% and lift: 1.3). CONCLUSION: Head circumference was related to cerebral volume. Due to its low cost and easy use, head circumference can be used as a screening test for microcephaly, adjusting it for gender and height. Microcephaly was associated with dementia at old age.
Palavras-chave
Adult, Microcephaly classification, Cephalometry, Dementia, Data Mining
Referências
- Abuelo Dianne, 2007, Semin Pediatr Neurol, V14, P118, DOI 10.1016/j.spen.2007.07.003
- Agrawal R., 1993, SIGMOD Record, V22, P207, DOI 10.1145/170035.170072
- Ashwal S, 2009, NEUROLOGY, V73, P887, DOI 10.1212/WNL.0b013e3181b783f7
- Baare WFC, 2001, CEREB CORTEX, V11, P816, DOI 10.1093/cercor/11.9.816
- Bartholomeusz HH, 2002, NEUROPEDIATRICS, V33, P239, DOI 10.1055/s-2002-36735
- Bzdok D, 2018, BIOL PSYCHIAT-COGN N, V3, P223, DOI 10.1016/j.bpsc.2017.11.007
- Chang S, 2017, INT J GERIATR PSYCH, V32, pE1, DOI 10.1002/gps.4643
- Chelly J, 2001, NAT REV GENET, V2, P669, DOI 10.1038/35088558
- Ferretti Renata Eloah de Lucena, 2010, Dement. neuropsychol., V4, P138, DOI 10.1590/S1980-57642010DN40200011
- Ferretti-Rebustini Renata Eloah de Lucena, 2015, Dement. neuropsychol., V9, P103, DOI 10.1590/1980-57642015DN92000004
- Graves AB, 1996, BRIT J PSYCHIAT, V169, P86, DOI 10.1192/bjp.169.1.86
- Grinberg Lea Tenenholz, 2007, Cell and Tissue Banking, V8, P151, DOI 10.1007/s10561-006-9022-z
- Harrison JK, 2016, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD011333.pub2
- Hshieh TT, 2016, INT PSYCHOGERIATR, V28, P157, DOI 10.1017/S104161021500037X
- ILLINGWO.RS, 1971, ACTA PAEDIATR SCAND, V60, P333, DOI 10.1111/j.1651-2227.1971.tb06666.x
- ISHIKAWA T, 1987, ACTA PAEDIATR SCAND, V76, P824, DOI 10.1111/j.1651-2227.1987.tb10571.x
- JORM AF, 1994, PSYCHOL MED, V24, P145, DOI 10.1017/S003329170002691X
- Joshi S, 2006, MED CLIN N AM, V90, P769, DOI 10.1016/j.mcna.2006.05.014
- Kac G, 1999, Cad Saude Publica, V15, P451, DOI 10.1590/S0102-311X1999000300002
- KATZMAN R, 1988, ANN NEUROL, V23, P138, DOI 10.1002/ana.410230206
- KONISHI M, 1995, ANTHROPOL SCI, V103, P279, DOI 10.1537/ase.103.279
- Krauss MJ, 2003, AM J OBSTET GYNECOL, V188, P1484, DOI 10.1067/mob.2003.452
- Librenza-Garcia D, 2017, NEUROSCI BIOBEHAV R, V80, P538, DOI 10.1016/j.neubiorev.2017.07.004
- MORRIS JC, 1993, NEUROLOGY, V43, P2412, DOI 10.1212/WNL.43.11.2412-a
- Mortimer JA, 2003, J CLIN EXP NEUROPSYC, V25, P671, DOI 10.1076/jcen.25.5.671.14584
- Nunes PV, 2018, J AFFECT DISORDERS, V241, P176, DOI 10.1016/j.jad.2018.08.025
- Nunes PV, 2018, INT J GERIATR PSYCH, V33, P14, DOI 10.1002/gps.4649
- OPITZ JM, 1990, J CRAN GENET DEV BIO, V10, P175
- OUNSTED M, 1985, ARCH DIS CHILD, V60, P936, DOI 10.1136/adc.60.10.936
- Raz N, 2006, NEUROSCI BIOBEHAV R, V30, P730, DOI 10.1016/j.neubiorev.2006.07.001
- ROCHE AF, 1986, HUM BIOL, V58, P893
- Son SJ, 2012, ARCH GERONTOL GERIAT, V54, P343, DOI 10.1016/j.archger.2011.05.025
- Suemoto CK, 2013, INT J GERIATR PSYCH, V28, P487, DOI 10.1002/gps.3850
- Tie K, 2012, ARTHROSCOPY, V28, P1464, DOI 10.1016/j.arthro.2012.04.053
- Wang F, 2019, NEUROEPIDEMIOLOGY, V53, P152, DOI 10.1159/000501103
- WEAVER DD, 1980, J PEDIATR-US, V96, P990, DOI 10.1016/S0022-3476(80)80623-8
- Woodward M, 2003, DIABETES CARE, V26, P360
- World Health Organization, 2021, HEAD CIRCUMFERENCE F
Coleções
Artigos e Materiais de Revistas Científicas - FM/MPT
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - FM/MNE
Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/IPq
Carregar mais Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - FM/MNE
Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/IPq