New Prognostic Score for Stable Coronary Disease Evaluation

Carregando...
Imagem de Miniatura
Citações na Scopus
3
Tipo de produção
article
Data de publicação
2011
Título da Revista
ISSN da Revista
Título do Volume
Editora
ARQUIVOS BRASILEIROS CARDIOLOGIA
Citação
ARQUIVOS BRASILEIROS DE CARDIOLOGIA, v.96, n.5, p.411-418, 2011
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: The need to improve the exercise testing accuracy, pushed the development of scores, whose applicability was already broadly recognized. Objective: Prognostic evaluation of stable coronary disease through a new simplified score. Methods: A new score was applied in 372 multivessel coronary patients with preserved ventricular function, 71.8% male, age: 59.5 (+/- 9.07) years old, randomized to medical treatment, surgery (CABG) or angioplasty (PTCA), with 5 years of follow-up. Cardiovascular death was considered the primary endpoint. Non-fatal myocardial infarction, death and re-intervention were considered for a combined secondary endpoint. The score was based on an equation previously validated, resulting from a sum of one point for: male gender, infarction history, angina, diabetes, insulin use and one point for each decade of life after 40 years old. Positive exercise testing summed one additional point. Results: Thirty six deaths was observed (10 in group PTCA, 15 in CABG and 11 in the clinical group), p = 0.61. We observed 93 combined events: 37 in PTCA group, 23 in CABG and 33 in the clinical group (p = 0.058). 247 patients presented clinical score >= 5 points and 216 >= 6 points. The cutoff point >= 5 or >= 6 points identified higher risk, p = 0.015 and p = 0.012, respectively. The survival curve showed a different death incidence after the randomization when score reached 06 points or more (p = 0.07), and a distinct incidence of combined events between the patients with score < 6 and >= 6 points (p = 0.02). Conclusion: The new score was consistent for multiarterial stable coronary disease risk stratification. (Arq Bras Cardiol 2011;96(5):411-419)
Palavras-chave
Exercise test, coronary disease, angina pectoris, prognosis
Referências
  1. Wilson PWF, 1998, CIRCULATION, V97, P1837
  2. Do D, 1997, CHEST, V111, P1742, DOI 10.1378/chest.111.6.1742
  3. Prakash M, 2001, CHEST, V120, P1003, DOI 10.1378/chest.120.3.1003
  4. KANNEL WB, 1979, AM J CARDIOL, V44, P53, DOI 10.1016/0002-9149(79)90250-9
  5. Morise AP, 2003, J AM COLL CARDIOL, V42, P842, DOI 10.1016/S0735-1097(03)00837-4
  6. MORISE AP, 1992, J AM COLL CARDIOL, V20, P1187
  7. Gibbons RJ, 2002, CIRCULATION, V106, P1883, DOI 10.1161/01.CIR.0000034670.06526.15
  8. Fox KM, 2003, LANCET, V362, P782
  9. Soares PR, 2006, CIRCULATION, V114, pI420, DOI 10.1161/CIRCULATIONAHA.105.000679
  10. MARK DB, 1987, ANN INTERN MED, V106, P793
  11. Poornima IG, 2004, J AM COLL CARDIOL, V43, P194, DOI 10.1016/j.jacc.2003.09.029
  12. Poole-Wilson PA, 2004, LANCET, V364, P849, DOI 10.1016/S0140-6736(04)16980-8
  13. Koide Y, 2001, AM J CARDIOL, V87, P142, DOI 10.1016/S0002-9149(00)01305-9
  14. COX DR, 1972, J R STAT SOC B, V34, P187
  15. Yusuf S, 2000, NEW ENGL J MED, V342, P145
  16. Singh M, 2004, CIRCULATION, V109, P2727, DOI 10.1161/01.CIR.0000131898.18849.65
  17. Ashley EA, 2000, LANCET, V356, P1592, DOI 10.1016/S0140-6736(00)03138-X
  18. PRYOR DB, 1991, AM J MED, V90, P553
  19. Brito FS, 2002, ARQ BRAS CARDIOL, V78, P1, DOI 10.1590/S0066-782X2002000800001
  20. BRUCE R A, 1956, Mod Concepts Cardiovasc Dis, V25, P321
  21. DETRANO R, 1992, COMPUT BIOMED RES, V25, P468, DOI 10.1016/0010-4809(92)90004-T
  22. DIAMOND GA, 1979, NEW ENGL J MED, V300, P1350, DOI 10.1056/NEJM197906143002402
  23. Froelicher V, 2002, PROG CARDIOVASC DIS, V44, P395, DOI 10.1053/pcad.2002.122693
  24. GIBBONS RJ, 1993, CARDIOVASCULAR HLTH, P73
  25. Ho KT, 2002, MAYO CLIN PROC, V77, P515
  26. HOLLENBERG M, 1980, CIRCULATION, V61, P276
  27. HUBBARD BL, 1992, ARCH INTERN MED, V152, P309, DOI 10.1001/archinte.152.2.309
  28. HUEB WA, 1995, J AM COLL CARDIOL, V26, P1600, DOI 10.1016/0735-1097(95)00384-3
  29. Lu Z Y, 1993, J Tongji Med Univ, V13, P177
  30. Mansur AP, 2004, ARQ BRAS CARDIOL S2, V83, P7
  31. MARK DB, 1991, NEW ENGL J MED, V325, P849, DOI 10.1056/NEJM199109193251204
  32. KAPLAN EL, 1958, J AM STAT ASSOC, V53, P457, DOI 10.2307/2281868
  33. Mora S, 2005, CIRCULATION, V112, P1566, DOI 10.1161/CIRCULATIONAHA.105.542993
  34. MORROW K, 1993, ANN INTERN MED, V118, P689
  35. Raxwal V, 2001, CHEST, V119, P1933, DOI 10.1378/chest.119.6.1933
  36. Villela M, 2003, AM HEART J, V145, P475, DOI 10.1067/mhj.2003.162
  37. Yamada H, 1997, PROG CARDIOVASC DIS, V39, P457, DOI 10.1016/S0033-0620(97)80040-0