Pregnancy, Viral Infection, and COVID-19

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorALBERCA, Ricardo Wesley
dc.contributor.authorPEREIRA, Natalli Zanete
dc.contributor.authorOLIVEIRA, Luanda Mara Da Silva
dc.contributor.authorGOZZI-SILVA, Sarah Cristina
dc.contributor.authorSATO, Maria Notomi
dc.date.accessioned2020-08-20T13:26:21Z
dc.date.available2020-08-20T13:26:21Z
dc.date.issued2020
dc.description.abstractPregnancy comprises a unique immunological condition, to allow fetal development and to protect the host from pathogenic infections. Viral infections during pregnancy can disrupt immunological tolerance and may generate deleterious effects on the fetus. Despite these possible links between pregnancy and infection-induced morbidity, it is unclear how pregnancy interferes with maternal response to some viral pathogens. In this context, the novel coronavirus (SARS-CoV-2) can induce the coronavirus diseases-2019 (COVID-19) in pregnant women. The potential risk of vertical transmission is unclear, babies born from COVID-19-positive mothers seems to have no serious clinical symptoms, the possible mechanisms are discussed, which highlights that checking the children's outcome and more research is warranted. In this review, we investigate the reports concerning viral infections and COVID-19 during pregnancy, to establish a correlation and possible implications of COVID-19 during pregnancy and neonatal's health.eng
dc.description.indexMEDLINEeng
dc.description.sponsorshipFAPESPFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [19/02679-7, 19/07976-0, 19/22448-0]
dc.identifier.citationFRONTIERS IN IMMUNOLOGY, v.11, article ID 1672, 12p, 2020
dc.identifier.doi10.3389/fimmu.2020.01672
dc.identifier.issn1664-3224
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/37087
dc.language.isoeng
dc.publisherFRONTIERS MEDIA SAeng
dc.relation.ispartofFrontiers in Immunology
dc.rightsopenAccesseng
dc.rights.holderCopyright FRONTIERS MEDIA SAeng
dc.subjectCOVID-19eng
dc.subjectSARS-CoV-2eng
dc.subjectpregnancyeng
dc.subjectneonataleng
dc.subjectimmunologyeng
dc.subject.otheracute respiratory syndromeeng
dc.subject.othermaternal-fetal interfaceeng
dc.subject.otherregulatory t-cellseng
dc.subject.othertnf-alphaeng
dc.subject.otherinfluenza immunizationeng
dc.subject.othernonpregnant womeneng
dc.subject.otherimmune-mechanismseng
dc.subject.otherneonates borneng
dc.subject.otherzika viruseng
dc.subject.othermers-coveng
dc.subject.wosImmunologyeng
dc.titlePregnancy, Viral Infection, and COVID-19eng
dc.typearticleeng
dc.type.categoryrevieweng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalGOZZI-SILVA, Sarah Cristina:Univ Sao Paulo, Inst Biomed Sci, Sao Paulo, Brazil
hcfmusp.author.externalSATO, Maria Notomi:Univ Sao Paulo, Inst Biomed Sci, Sao Paulo, Brazil
hcfmusp.citation.scopus71
hcfmusp.contributor.author-fmusphcRICARDO WESLEY ALBERCA CUSTODIO
hcfmusp.contributor.author-fmusphcNATALLI ZANETE PEREIRA
hcfmusp.contributor.author-fmusphcLUANDA MARA DA SILVA OLIVEIRA
hcfmusp.description.articlenumber1672
hcfmusp.description.volume11
hcfmusp.origemWOS
hcfmusp.origem.pubmed32733490
hcfmusp.origem.scopus2-s2.0-85088476038
hcfmusp.origem.wosWOS:000553412700001
hcfmusp.publisher.cityLAUSANNEeng
hcfmusp.publisher.countrySWITZERLANDeng
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