Risk Factors for the Impairment of Ambulation in Older People Hospitalized with COVID-19: A Retrospective Cohort Study

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSILVA, E. C. G. E.
dc.contributor.authorSCHMITT, A. C. B.
dc.contributor.authorGODOY, C. G. de
dc.contributor.authorOLIVEIRA, D. B. de
dc.contributor.authorTANAKA, C.
dc.contributor.authorTOUFEN, C. Jr.
dc.contributor.authorCARVALHO, C. R. R. de
dc.contributor.authorCARVALHO, C. R. F.
dc.contributor.authorFU, C.
dc.contributor.authorHILL, K. D.
dc.contributor.authorPOMPEU, J. E.
dc.date.accessioned2024-03-13T19:54:03Z
dc.date.available2024-03-13T19:54:03Z
dc.date.issued2023
dc.description.abstract(1) Background: Some older people hospitalized with COVID-19 have experienced reduced ambulation capacity. However, the prevalence of the impairment of ambulation capacity still needs to be established. Objective: To estimate the prevalence of, and identify the risk factors associated with, the impairment of ambulation capacity at the point of hospital discharge for older people with COVID-19. (2) Methods: A retrospective cohort study. Included are those with an age > 60 years, of either sex, hospitalized due to COVID-19. Clinical data was collected from patients’ medical records. Ambulation capacity prior to COVID-19 infection was assessed through the patients’ reports from their relatives. Multiple logistic regressions were performed to identify the risk factors associated with the impairment of ambulation at hospital discharge. (3) Results: Data for 429 older people hospitalized with COVID-19 were randomly collected from the medical records. Among the 56.4% who were discharged, 57.9% had reduced ambulation capacity. Factors associated with reduced ambulation capacity at discharge were a hospital stay longer than 20 days (Odds Ratio (OR): 3.5) and dependent ambulation capacity prior to COVID-19 (Odds Ratio (OR): 11.3). (4) Conclusion: More than half of the older people who survived following hospitalization due to COVID-19 had reduced ambulation capacity at hospital discharge. Impaired ambulation prior to the infection and a longer hospital stay were risks factors for reduced ambulation capacity.eng
dc.description.indexMEDLINE
dc.description.indexPubMed
dc.description.indexScopus
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo, FAPESP
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq, (19618-8/2018)
dc.identifier.citationINTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v.20, n.22, article ID 7057, p, 2023
dc.identifier.doi10.3390/ijerph20227057
dc.identifier.issn1661-7827
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/58619
dc.language.isoeng
dc.publisherMULTIDISCIPLINARY DIGITAL PUBLISHING INSTITUTE (MDPI)eng
dc.relation.ispartofInternational Journal of Environmental Research and Public Health
dc.rightsopenAccesseng
dc.rights.holderCopyright MULTIDISCIPLINARY DIGITAL PUBLISHING INSTITUTE (MDPI)eng
dc.subjectCOVID-19eng
dc.subjectfunctional statuseng
dc.subjecthospitalizationeng
dc.subjectolder peopleeng
dc.subject.otheragedeng
dc.subject.othercovid-19eng
dc.subject.otherhospitalizationeng
dc.subject.otherhumanseng
dc.subject.othermiddle agedeng
dc.subject.otherretrospective studieseng
dc.subject.otherrisk factorseng
dc.subject.otherwalkingeng
dc.subject.othercohort analysiseng
dc.subject.othercovid-19eng
dc.subject.otherelderly populationeng
dc.subject.otherhealth careeng
dc.subject.otherhospital sectoreng
dc.subject.otherpublic healtheng
dc.subject.otherrisk factoreng
dc.subject.otheradulteng
dc.subject.otheragedeng
dc.subject.otherarticleeng
dc.subject.othercohort analysiseng
dc.subject.othercoronavirus disease 2019eng
dc.subject.otherdyslipidemiaeng
dc.subject.otherfemaleeng
dc.subject.otherfunctional statuseng
dc.subject.otherhospital dischargeeng
dc.subject.otherhospital patienteng
dc.subject.otherhospitalizationeng
dc.subject.otherhumaneng
dc.subject.otherin-hospital mortalityeng
dc.subject.otherintensive care uniteng
dc.subject.otherlength of stayeng
dc.subject.othermaleeng
dc.subject.otherneurologic diseaseeng
dc.subject.otherobesityeng
dc.subject.otherprevalenceeng
dc.subject.otherretrospective studyeng
dc.subject.otherrisk factoreng
dc.subject.othertobacco useeng
dc.subject.othervery elderlyeng
dc.subject.otherwalking difficultyeng
dc.subject.othercoronavirus disease 2019eng
dc.subject.othermiddle agedeng
dc.subject.otherrisk factoreng
dc.subject.otherwalkingeng
dc.titleRisk Factors for the Impairment of Ambulation in Older People Hospitalized with COVID-19: A Retrospective Cohort Studyeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.affiliation.countryAustrália
hcfmusp.affiliation.countryisoau
hcfmusp.author.externalHILL, K. D.:Rehabilitation Ageing and Independent Living (RAIL) Research Centre, Monash University, Melbourne, 3199, VIC, Australia
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcERIKA CHRISTINA GOUVEIA E SILVA
hcfmusp.contributor.author-fmusphcANA CAROLINA BASSO SCHMITT
hcfmusp.contributor.author-fmusphcCAROLINE GIL DE GODOY
hcfmusp.contributor.author-fmusphcDANIELLE BRANCOLINI DE OLIVEIRA
hcfmusp.contributor.author-fmusphcCLARICE TANAKA
hcfmusp.contributor.author-fmusphcCARLOS TOUFEN JUNIOR
hcfmusp.contributor.author-fmusphcCARLOS ROBERTO RIBEIRO DE CARVALHO
hcfmusp.contributor.author-fmusphcCELSO RICARDO FERNANDES DE CARVALHO
hcfmusp.contributor.author-fmusphcCAROLINA FU
hcfmusp.contributor.author-fmusphcJOSE EDUARDO POMPEU
hcfmusp.description.articlenumber7057
hcfmusp.description.issue22
hcfmusp.description.volume20
hcfmusp.origemSCOPUS
hcfmusp.origem.dimensionspub.1165920926
hcfmusp.origem.pubmed37998288
hcfmusp.origem.scopus2-s2.0-85177755069
hcfmusp.relation.referenceZisberg A., Shadmi E., Sinoff G., Gur-Yaish N., Srulovici E., Admi H., Low mobility during hospitalization and functional decline in older adults, J. Am. Geriatr. Soc, 59, pp. 266-273, (2011)eng
hcfmusp.relation.referenceMahoney J.E., Sager M.A., Jalaluddin M., New walking dependence associated with hospitalization for acute medical illness: Incidence and significance, J. Gerontol. A Biol. Sci. Med. Sci, 53, pp. M307-M312, (1998)eng
hcfmusp.relation.referenceMedina-Mirapeix F., Bernabeu-Mora R., Garcia-Guillamon G., Valera Novella E., Gacto-Sanchez M., Garcia-Vidal J.A., Patterns, Trajectories, and Predictors of Functional Decline after Hospitalization for Acute Exacerbations in Men with Moderate to Severe Chronic Obstructive Pulmonary Disease: A Longitudinal Study, PLoS ONE, 11, (2016)eng
hcfmusp.relation.referenceCoppo A., Bellani G., Winterton D., Di Pierro M., Soria A., Faverio P., Cairo M., Mori S., Messinesi G., Contro E., Et al., Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): A prospective cohort study, Lancet Respir. Med, 8, pp. 765-774, (2020)eng
hcfmusp.relation.referenceMorley J.E., Vellas B., Editorial: COVID-19 and Older Adults, J. Nutr. Health Aging, 24, pp. 364-365, (2020)eng
hcfmusp.relation.referenceWilliamson E.J., Walker A.J., Bhaskaran K., Bacon S., Bates C., Morton C.E., Curtis H.J., Mehrkar A., Evans D., Inglesby P., Et al., Factors associated with COVID-19-related death using Open SAFELY, Nature, 84, pp. 430-436, (2020)eng
hcfmusp.relation.referenceStatement on the Second Meeting of the International Health Regulations (2005) Emergency Committee Regarding the Outbreak of Novel Coronavirus (2019-nCoV), (2020)eng
hcfmusp.relation.referenceGrant M.C., Geoghegan L., Arbyn M., Mohammed Z., McGuinness L., Clarke E.L., Wade R.G., The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2eng
hcfmusp.relation.referenceCOVID-19): A systematic review and meta-analysis of 148 studies from 9 countries, PLoS ONE, 15, (2020)eng
hcfmusp.relation.referenceMeo S.A., Al-Khlaiwi T., Usmani A.M., Meo A.S., Klonoff D.C., Hoang T.D., Biological and epidemiological trends in the prevalence and mortality due to outbreaks of novel coronavirus COVID-19, J. King. Saud. Univ. Sci, 32, pp. 2495-2499, (2020)eng
hcfmusp.relation.referenceChen N., Zhou M., Dong X., Qu J., Gong F., Han Y., Qiu Y., Wang J., Liu Y., Wei Y., Et al., Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study, Lancet, 395, pp. 507-513, (2020)eng
hcfmusp.relation.referenceChan J.F., Yuan S., Kok K.H., To K.K., Chu H., Yang J., Xing F., Liu J., Yip C.C., Poon R.W., Et al., A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster, Lancet, 395, pp. 514-523, (2020)eng
hcfmusp.relation.referenceXu X., Chen P., Wang J., Feng J., Zhou H., Li X., Zhong W., Hao P., Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission, Sci. China Life Sci, 63, pp. 457-460, (2020)eng
hcfmusp.relation.referenceTamara A., Tahapary D.L., Obesity as a predictor for a poor prognosis of COVID-19: A systematic review, Diabetes Metab. Syndr, 14, pp. 655-659, (2020)eng
hcfmusp.relation.referenceWelch C., Greig C., Masud T., Wilson D., Jackson T.A., COVID-19 and Acute Sarcopenia, Aging Dis, 11, pp. 1345-1351, (2020)eng
hcfmusp.relation.referenceChen Y., Klein S.L., Garibaldi B.T., Li H., Wu C., Osevala N.M., Li T., Margolick J.B., Pawelec G., Leng S.X., Aging in COVID-19: Vulnerability, immunity and intervention, Ageing Res. Rev, 65, (2021)eng
hcfmusp.relation.referenceKortebein P., Ferrando A., Lombeida J., Wolfe R., Evans W.J., Effect of 10 days of bed rest on skeletal muscle in healthy older adults, JAMA, 297, pp. 1772-1774, (2007)eng
hcfmusp.relation.referenceMarino D.M., Marrara K.T., Arcuri J.F., Candolo C., Jamami M., Pires Di Lorenzo V.A., Determination of exacerbation predictors in patients with COPD in physical therapy—A longitudinal study, Braz. J. Phys. Ther, 18, pp. 127-136, (2014)eng
hcfmusp.relation.referenceRawal G., Yadav S., Kumar R., Post-intensive Care Syndrome: An Overview, J. Transl. Int. Med, 5, pp. 90-92, (2017)eng
hcfmusp.relation.referenceNiu S., Tian S., Lou J., Kang X., Zhang L., Lian H., Zhang J., Clinical characteristics of older patients infected with COVID-19: A descriptive study, Arch. Gerontol. Geriatr, 89, (2020)eng
hcfmusp.relation.referenceFerrando C., Suarez-Sipmann F., Mellado-Artigas R., Hernandez M., Gea A., Arruti E., Aldecoa C., Martinez-Palli G., Martinez-Gonzalez M.A., Slutsky A.S., Et al., Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS, Intensive Care Med, 46, pp. 2200-2211, (2020)eng
hcfmusp.relation.referenceGardashkhani S., Ajri-Khameslou M., Heidarzadeh M., Rajaei Sedigh S., Post-Intensive Care Syndrome in COVID-19 Patients Discharged from the Intensive Care Unit, J. Hosp. Palliat. Nurs, 23, pp. 530-538, (2021)eng
hcfmusp.relation.referencePeghin M., Palese A., Venturini M., De Martino M., Gerussi V., Graziano E., Bontempo G., Marrella F., Tommasini A., Fabris M., Et al., Post-COVID-19 symptoms 6 months after acute infection among hospitalized and non-hospitalized patients, Clin. Microbiol. Infect, 27, pp. 1507-1513, (2021)eng
hcfmusp.relation.referenceSimpson R., Robinson L., Rehabilitation following critical illness in people with COVID-19 infection, Am. J. Phys. Med. Rehabil, 99, pp. 470-474, (2020)eng
hcfmusp.relation.referenceSilva E.C.G., Godoy C.G., Gambeta A.C., Schmitt A.C.B., Fu C., Tanaka C., Carvalho C.R.F., Toufen Junior C., Carvalho C., Pompeu J.E., Ambulation Capacity, Age, Immunosuppression, And Mechanical Ventilation Are Risk Factors Of In-Hospital Death In Severe COVID-19: A Cohort Study, Clinics, 77, (2022)eng
hcfmusp.relation.referenceKamdar B.B., Huang M., Dinglas V.D., Colantuoni E., von Wachter T.M., Hopkins R.O., Needham D.M., Joblessness and lost earnings after acute respiratory distress syndrome in a 1-year national multicenter study, Am. J. Respir. Crit. Care Med, 196, pp. 1012-1020, (2017)eng
hcfmusp.relation.referenceRydingsward J.E., Horkan C.M., Mogensen K.M., Quraishi S.A., Amrein K., Christopher K.B., Functional status in ICU survivors and out of hospital outcomes: A cohort study, Crit. Care Med, 44, pp. 869-879, (2016)eng
hcfmusp.relation.referenceVrettou C.S., Mantziou V., Vassiliou A.G., Orfanos S.E., Kotanidou A., Dimopoulou I., Post-Intensive Care Syndrome in Survivors from Critical Illness including COVID-19 Patients: A Narrative Review, Life, 12, (2022)eng
hcfmusp.relation.referenceBerlinska A., Swiatkowska-Stodulska R., Sworczak K., Old Problem, New Concerns: Hypercortisolemia in the Time of COVID-19, Front. Endocrinol, 5, (2021)eng
hcfmusp.relation.referenceEstatuto do Idoso/Ministério da Saúde, (2009)eng
hcfmusp.relation.referenceMehrholz J., Wagner K., Rutte K., Meissner D., Pohl M., Predictive validity and responsiveness of the functional ambulation category in hemiparetic patients after stroke, Arch. Phys. Med. Rehabil, 88, pp. 1314-1319, (2007)eng
hcfmusp.relation.referenceLamontagne F., Agarwal A., Rochwerg B., Siemieniuk R.A., Agoritsas T., Askie L., Lytvyn L., Agarwal A., Leo Y.-S., Macdonald H., Et al., A living WHO guideline on drugs for COVID-19, BMJ, 370, (2020)eng
hcfmusp.relation.referencePal C., Fu C., Carvalho C.R.R., Auler Junior J.O.C., Yamauchi L.Y., Association of the mobility level of critically ill adult patients with the success of extubation: Protocol for a cohort study, BMJ Open, 11, (2021)eng
hcfmusp.relation.referenceKemp H.I., Corner E., Colvin L.A., Chronic Pain after COVID-19: Implications for Rehabilitation, Br. J. Anaesth, 125, pp. 436-440, (2020)eng
hcfmusp.relation.referenceRanzani O.T., Bastos L.S.L., Gelli J.G.M., Marchesi J.F., Baiao F., Hamacher S., Bozza F.A., Characterisation of the first 250,000 hospital admissions for COVID-19 in Brazil: A retrospective analysis of nationwide data, Lancet Respir. Med, 9, pp. 407-418, (2021)eng
hcfmusp.relation.referenceTavares G.S., Oliveira C.C., Mendes L.P.S., Velloso M., Muscle strength and mobility of individuals with COVID-19 compared with non-COVID-19 in intensive care, Heart Lung, 62, pp. 233-239, (2023)eng
hcfmusp.relation.referenceMeftahi G.H., Jangravi Z., Sahraei H., Bahari Z., The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: The contribution of “inflame-aging, Inflamm. Res, 69, pp. 825-839, (2020)eng
hcfmusp.relation.referenceMartin J., Padierna A., Anton-Ladislao A., Moro I., Quintana J.M., Predictors of mortality during hospitalization and 3 months after discharge in elderly people with and without dementia, Aging Ment. Health, 23, pp. 1057-1065, (2019)eng
hcfmusp.relation.referenceSchujmann D.S., Lunardi A.C., Peso C.N., Pompeu J.E., Annoni R., Miura M.C., de Censo C.M., Taniguchi L.N.T., de Moraes Regenga M., de Campos E.C., Et al., Functional Recovery Groups in Critically Ill COVID-19 Patients and Their Associated Factors: From ICU to Hospital Discharge*, Crit. Care Med, 50, pp. 1799-1808, (2022)eng
hcfmusp.relation.referenceMoura E.C., Silva EN da Sanchez M.N., Cavalcante F.V., Oliveira LG de Oliveira A., Frio G.S., Santos L.M.P., Timely Availability of Public Data for Health Management: COVID-19 Wave’s Analysiseng
hcfmusp.relation.referencePerrotta F., Corbi G., Mazzeo G., Boccia M., Aronne L., D'agnano V., Komici K., Mazzarella G., Parrella R., Bianco A., COVID-19 and the elderly: Insights into pathogenesis and clinical decision-making, Aging Clin. Exp. Res, 32, pp. 1599-1608, (2020)eng
hcfmusp.relation.referenceStam H.J., Stucki G., Bickenbach J., COVID-19 and Post Intensive Care Syndrome: A Call for Action, J. Rehabil. Med, 52, (2020)eng
hcfmusp.relation.referenceSilva Andrade B., Siqueira S., de Assis Soares W.R., de Souza Rangel F., Santos N.O., Dos Santos Freitas A., Ribeiro da Silveira P., Tiwari S., Alzahrani K.J., Goes-Neto A., Et al., Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms, Viruses, 13, (2021)eng
hcfmusp.relation.referenceJaffri A., Jaffri U.A., Post-Intensive care syndrome and COVID-19: Crisis after a crisis?, Heart Lung, 49, pp. 883-884, (2020)eng
hcfmusp.relation.referenceFreitas A.R., Napimoga M., Donalisio M.R., Avaliando a gravidade do COVID-19, Epidemiol. Saúde, 29, (2020)eng
hcfmusp.relation.referenceOchiai G.S., Godoy C.G., Silva E.C.G., Oliveira D.B., Silva E.M., Viana B.O.C., Silva S.M.D., Souza R.O.B., Campos C.M., Schmitt A.C.B., Et al., Functional impact on adults and older people after hospitalization by COVID-19, Physiother. Res. Int, 28, (2023)eng
hcfmusp.relation.referenceGodoy C.G., Silva E.C.G., Oliveira D.B., Silva E.M., Campos C.M., Gambeta A.C., Carvalho C.R.F., Fu C., Schmitt A.C.B., Tanaka C., Et al., Protocol for Functional Assessment of Adults and Older Adults After Hospitalization by COVID-19, Clinics, 76, (2021)eng
hcfmusp.relation.referenceAlonso A.C., Silva-Santos P.R., Quintana M.S.L., Silva V.C.D., Brech G.C., Barbosa L.G., Pompeu J.E., Silva E., Silva E.M.D., Godoy C.G.D., Et al., Physical and Pulmonary Capacities of Individuals with Severe Coronavirus Disease After Hospital Discharge: A Preliminary Cross-Sectional Study Based On Cluster Analysis, Clinics, 76, (2021)eng
hcfmusp.scopus.lastupdate2024-05-17
relation.isAuthorOfPublication2b6e0a50-d84d-4e49-9648-27d61e7bac6a
relation.isAuthorOfPublicationb58e765f-ddb1-423b-9cd7-4262888f8d8a
relation.isAuthorOfPublicationbdbe701e-a52b-4304-a083-06443f609a5b
relation.isAuthorOfPublication400963aa-d8d7-4cd6-ae66-e7d7411326bb
relation.isAuthorOfPublication5cafb5db-e92f-4732-b4d7-97076cc5f269
relation.isAuthorOfPublicationf94ce93a-e473-4f8c-b3cc-93bf37a0accc
relation.isAuthorOfPublicationf1b24304-c10c-4be9-95d8-010b78bf2a73
relation.isAuthorOfPublication0f1363e9-60e5-4fc3-ada9-4d80cfb6f4bf
relation.isAuthorOfPublicationc6be8ca3-188b-46ea-93b8-1679153a7782
relation.isAuthorOfPublicatione6a7d63e-916b-4ed8-b573-a204e6a12fdd
relation.isAuthorOfPublication.latestForDiscovery2b6e0a50-d84d-4e49-9648-27d61e7bac6a
Arquivos
Coleções
Artigos e Materiais de Revistas Científicas - FM/MFT
Artigos e Materiais de Revistas Científicas - COVID-19
Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/09
Carregar mais