Anti-MOG (Myelin Oligodendrocyte Glycoprotein)-Positive Severe Optic Neuritis with Optic Disc Ischaemia and Macular Star

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Citações na Scopus
12
Tipo de produção
article
Data de publicação
2015
Título da Revista
ISSN da Revista
Título do Volume
Editora
TAYLOR & FRANCIS AS
Citação
NEURO-OPHTHALMOLOGY, v.39, n.6, p.285-288, 2015
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
A 44-year-old man presented with severe right visual loss. The right fundus examination showed marked optic disc oedema associated with partial macular star. Serological blood tests for infectious agents were all negative. Serum aquaporin-4 antibody was negative but anti-MOG (myelin oligodendrocyte glycoprotein) was positive. Magnetic resonance revealed extensive lesion in right optic nerve. There was no visual improvement after intravenous therapy. Patient had no further attacks after follow-up. Optic disc oedema with macular star is found in several infectious and non-inflammatory disorders, but it has not been reported in optic neuritis (ON) associated with autoantibodies to myelin oligodendrocyte glycoprotein (anti-MOG).
Palavras-chave
Devic's syndrome, macular star, multiple sclerosis, myelin oligodendrocyte glycoprotein antibody, optic neuritis
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