FREDERICO CASTELO MOURA
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
11 resultados
Resultados de Busca
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conferenceObject Bariatric Surgery as Treatment of Primary Pseudotumor Cerebri in a Male Adolescent: Case Report(2018) YBARRA, Marina; SANTOS, Tiago Jeronimo dos; QUEIROZ, Edjane Santos; RACHID, Ludmilla; FRANCO, Ruth Rocha; COMINATO, Louise; MOURA, Frederico Castelo; VELHOTE, Manoel Carlos; DAMIANI, Durval- Optociliary Shunt Vessels: Role in Diagnosis and Treatment of Atypical Pseudotumor Cerebri(2017) MOURA, Frederico Castelo; FORTINI, IdaA 46-year-old man presented with severe visual loss and optic atrophy associated with optociliary shunt vessels. The diagnostic work-up revealed intracranial hypertension and cerebral venous sinus stenosis, with no evidence of previous thrombosis. In view of the severe visual dysfunction, both eyes were submitted to optic nerve sheath fenestration. After surgery, a regression of collateral vessels was observed in both eyes.
- Anti-MOG (Myelin Oligodendrocyte Glycoprotein)-Positive Severe Optic Neuritis with Optic Disc Ischaemia and Macular Star(2015) MOURA, Frederico Castelo; SATO, Douglas Kazutoshi; RIMKUS, Carolina Medeiros; APOSTOLOS-PEREIRA, Samira Luisa; OLIVEIRA, Luana Michelli de; LEITE, Claudia Costa; FUJIHARA, Kazuo; MONTEIRO, Mario Luiz Ribeiro; CALLEGARO, DagobertoA 44-year-old man presented with severe right visual loss. The right fundus examination showed marked optic disc oedema associated with partial macular star. Serological blood tests for infectious agents were all negative. Serum aquaporin-4 antibody was negative but anti-MOG (myelin oligodendrocyte glycoprotein) was positive. Magnetic resonance revealed extensive lesion in right optic nerve. There was no visual improvement after intravenous therapy. Patient had no further attacks after follow-up. Optic disc oedema with macular star is found in several infectious and non-inflammatory disorders, but it has not been reported in optic neuritis (ON) associated with autoantibodies to myelin oligodendrocyte glycoprotein (anti-MOG).
- Recurrent idiopathic neuroretinitis as a spectrum of atypical optic neuritis: a case report and literature review(2018) VITURINO, Marina Goncalves Monteiro; MOURA, Frederico CasteloRecurrent idiopathic neuroretinitis is an inflammatory optic neuropathy characterized by optic nerve edema and macular star, associated with painless and recurrent episodes of visual loss, poor visual prognosis, and visual field defects related to nerve fiber layer injury. The disorder is sometimes mistaken for atypical optic neuritis. However, early diagnosis is important for visual recovery. Long-term immunosuppression has been shown to reduce the rate of recurrence and protect against severe and irreversible vision loss.
- Síndrome ocular isquêmica simulando retinopatia diabética unilateral: relato de caso e revisão da literatura(2012) MOURA, Frederico Castelo; TAKAHASHI, Vitor Kazuo Lotto; MINELLI, EduardoIschemic ocular syndrome (IOS) is caused by stenosis of carotid artery. Proliferative retinopathy is one of the signs and can lead to misdiagnosis with diabetic retinopathy. IOS must be considered in case of proliferative retinopathy asymmetric and refractory to laser treatment. Carotid endarterectomy in patients with IOS with no neurologic manifestations remains controversy. This paper reported a patient with IOS simulating diabetic retinopathy and treated with endarterectomy.
article 4 Citação(ões) na Scopus Linfoma não-Hodgkin bilateral do seio cavernoso como manifestação inicial da síndrome de imunodeficiência adquirida: relato de caso(2011) BARREIRA JUNIOR, Alan Kardec; MOURA, Frederico Castelo; MONTEIRO, Mario Luiz RibeiroCase report of bilateral cavernous sinus syndrome due to primary non-Hodgkin lymphoma of the central nervous system in a patient infected by the human immunodeficiency virus. A 51-year-old male patient infected by the human immunodeficiency virus but without antiretroviral treatment developed paralysis of the V and VI cranial nerves. Imaging studies were obtained to investigate an orbital apex and a cavernous sinus syndrome. A computerized tomography scan of the orbit was normal but a high-resolution magnetic resonance imaging demonstrated bilateral enlargement of the cavernous sinus. Although primary lymphoma of the central nervous system is a rare condition, it should be considered in the differential diagnosis in immunocompromised patients who develop ocular motility abnormalities and imaging signs suggestive of infiltrative cavernous sinus lesions.bookPart Neuropatia óptica traumática(2022) BASTIAN, Júlia Castelan; MOURA, Frederico Casteloarticle 2 Citação(ões) na Scopus Acometimento orbitário na doença de Rosai-Dorfman(2011) OLIVEIRA, Cristiana Dumaresq de; GONCALVES, Allan C. Pieroni; MOURA, Frederico Castelo; ROSSATO, Luiz Angelo; MONTEIRO, Mario Luiz RibeiroRosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare idiopathic and benign clinical entity, characterized by histiocytic proliferation with linfofagocitosis. It usually presents with cervical lymphadenopathy although extranodal involvement may occur. The orbital region is one of the most common extranodal sites. It is usually a self-limiting disease with spontaneous resolution but surgical excision, corticosteroids and radiotherapy may be necessary. We describe the case of a 29-years-old male patient complaining of an orbital mass sensation for 6 months and a history of previous sinus involvement from Rosai-Dorfman disease. Ophthalmic examination showed proptosis of the right eye and swelling of right lower eyelid. Computed tomography of the orbits disclosed a solid extraconal lesion in the inferior right orbit. After surgical excision there was a significant clinical improvement. Histopathologic examination confirmed the diagnosis of Rosai-Dorfman disease. We also review the clinical picture and differential diagnosis of this condition.article 7 Citação(ões) na Scopus Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis(2011) MOURA, Frederico C.; FERNANDES, Danilo B.; APOSTOLOS-PEREIRA, Samira L.; CALLEGARO, Dagoberto; MARCHIORI, Paulo E.; MONTEIRO, Mario L. R.Objective: To compare optical coherence tomography (OCT) measurements on the retinal nerve fiber layer (RNFL) of healthy controls and patients with longitudinally extensive transverse myelitis (LETM) without previous optic neuritis. Method: Twenty-six eyes from 26 patients with LETM and 26 control eyes were subjected to automated perimetry and OCT for comparison of RNFL measurements. Results: The mean deviation values from perimetry were significantly lower in patients with LETM than in controls (p<0.0001). RNFL measurements in the nasal quadrant and in the 3-o'clock segment were significantly smaller in LETM eyes than in controls. (p=0.04 and p=0.006, respectively). No significantly differences in other RNFL measurements were found. Conclusion: Patients with LETM may present localized RNFL loss, particularly on the nasal side of the optic disc, associated with slight visual field defects, even in the absence of previous episodes of optic neuritis. These findings emphasize the fact that patients with LETM may experience attacks of subclinical optic nerve damage.conferenceObject Autoantibody profile (MOG-IgG-seropositive, AQP4-IgG-seropositive and seronegativity) as a visual outcome predictor after optic neuritis(2017) VENTURA, L. M. G. B.; PITOMBEIRA, M. S.; GOMES, A. B. A. G. R.; MATOS, A. M. B.; PAOLILO, R. B.; TORRETTA, P. H. B.; SOLLA, D. J. F.; SALLES, L. M. O. P.; MOURA, F. C.; SATO, D. K.; SAMIRA, P. L. A.; CALLEGARO, D.