Pathogenesis of Pulmonary Hemorrhagic Syndrome in Human Leptospirosis

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorNICODEMO, Antonio C.
dc.contributor.authorDUARTE-NETO, Amaro Nunes
dc.date.accessioned2021-08-13T15:13:45Z
dc.date.available2021-08-13T15:13:45Z
dc.date.issued2021
dc.description.abstractBased on a previous study and by incorporating new knowledge, the goal of our study was to understand more fully the pathogenesis of hemorrhagic pneumonia of severe human leptospirosis, highlighting the onset of capillary lesions by Leptospira itself and/or its antigenic/toxic products acting on the endothelium and binding to cadherins. Both events lead to loss of endothelial integrity, alter permeability, cause rupture, and open intercellular junctions, contributing to the hemorrhagic phenomena associated with severe leptospirosis.eng
dc.description.indexMEDLINEeng
dc.identifier.citationAMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, v.104, n.6, p.1970-1972, 2021
dc.identifier.doi10.4269/ajtmh.20-1000
dc.identifier.eissn1476-1645
dc.identifier.issn0002-9637
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/41456
dc.language.isoeng
dc.publisherAMER SOC TROP MED & HYGIENEeng
dc.relation.ispartofAmerican Journal of Tropical Medicine and Hygiene
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright AMER SOC TROP MED & HYGIENEeng
dc.subject.wosPublic, Environmental & Occupational Healtheng
dc.subject.wosTropical Medicineeng
dc.titlePathogenesis of Pulmonary Hemorrhagic Syndrome in Human Leptospirosiseng
dc.typearticleeng
dc.type.categoryrevieweng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.citation.scopus5
hcfmusp.contributor.author-fmusphcANTONIO CARLOS NICODEMO
hcfmusp.contributor.author-fmusphcAMARO NUNES DUARTE NETO
hcfmusp.description.beginpage1970
hcfmusp.description.endpage1972
hcfmusp.description.issue6
hcfmusp.description.volume104
hcfmusp.origemWOS
hcfmusp.origem.pubmed33872210
hcfmusp.origem.scopus2-s2.0-85107448130
hcfmusp.origem.wosWOS:000657411500007
hcfmusp.publisher.cityMCLEANeng
hcfmusp.publisher.countryUSAeng
hcfmusp.relation.referenceBernardi FD, 2012, HUM PATHOL, V43, P1601, DOI 10.1016/j.humpath.2011.11.017eng
hcfmusp.relation.referenceDe Brito T, 2018, REV INST MED TROP SP, V60, DOI [10.1590/S1678-9946201860023, 10.1590/s1678-9946201860023]eng
hcfmusp.relation.referenceEvangelista K, 2014, PLOS NEGLECT TROP D, V8, DOI 10.1371/journal.pntd.0002672eng
hcfmusp.relation.referenceEvangelista KV, 2010, FUTURE MICROBIOL, V5, P1413, DOI 10.2217/FMB.10.102eng
hcfmusp.relation.referenceFraga TR, 2016, FRONT IMMUNOL, V7, DOI 10.3389/fimmu.2016.00623eng
hcfmusp.relation.referenceKochi LT, 2019, VIRULENCE, V10, P734, DOI 10.1080/21505594.2019.1650613eng
hcfmusp.relation.referenceMiyahara S, 2014, INT J EXP PATHOL, V95, P271, DOI 10.1111/iep.12085eng
hcfmusp.relation.referenceNicodemo AC, 1997, AM J TROP MED HYG, V56, P181, DOI 10.4269/ajtmh.1997.56.181eng
hcfmusp.relation.referenceSato H, 2017, PLOS NEGLECT TROP D, V11, DOI 10.1371/journal.pntd.0005830eng
hcfmusp.relation.referenceSmith S, 2019, PLOS NEGLECT TROP D, V13, DOI 10.1371/journal.pntd.0007929eng
hcfmusp.relation.referenceVieira ML, 2014, FEMS MICROBIOL LETT, V352, P129, DOI 10.1111/1574-6968.12349eng
hcfmusp.scopus.lastupdate2024-06-09
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relation.isAuthorOfPublication.latestForDiscovery059a0991-97bb-4c31-9941-4c7367eb4050
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Artigos e Materiais de Revistas Científicas - FM/MIP
Artigos e Materiais de Revistas Científicas - HC/ICHC
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