New Players in the Same Old Game: Disturbance of Group 2 Innate Lymphoid Cells in HIV-1 and Mycobacterium leprae Coinfected Patients

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art_PAPOTTO_New_Players_in_the_Same_Old_Game_Disturbance_2015.PDF (709.39 KB)
Citações na Scopus
1
Tipo de produção
article
Data de publicação
2015
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
PUBLIC LIBRARY SCIENCE
Autores
PAPOTTO, Pedro Henrique
MAEDA, Solange
TOMIMORI, Jane
XAVIER, Marilia Brasil
RIZZO, Luiz Vicente
CARVALHO, Karina Inacio
Citação
PLOS NEGLECTED TROPICAL DISEASES, v.9, n.9, article ID e0004030, 8p, 2015
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Leprosy control is achieved through a fine-tuning of T(H)1 and T(H)2 immune response pattern balance. Given the increasing epidemiological overlay of HIV and M. leprae infections, immune response in co-infected patients consists in an important contemporary issue. Here we describe for the first time the innate lymphoid cells compartment in peripheral blood of leprosy and HIV/M. leprae co-infected patients, and show that co-infection increases group 2 innate lymphoid whilst decreasing group 1 innate lymphoid cells frequencies and function.
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URI
https://observatorio.fm.usp.br/handle/OPI/12310
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/60
Artigos e Materiais de Revistas Científicas - ODS/03