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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | PILCHER, Christopher D. | - |
dc.contributor.author | BISOL, Claudia Alquati | - |
dc.contributor.author | PAGANELLA, Machline Paim | - |
dc.contributor.author | VALLABHANENI, Snigdha | - |
dc.contributor.author | MOTTA, Leonardo Rapone da | - |
dc.contributor.author | KATO, Sergio Kakuta | - |
dc.contributor.author | SPERHACKE, Rosa Dea | - |
dc.contributor.author | KALLAS, Esper G. | - |
dc.contributor.author | HECHT, Frederick M. | - |
dc.contributor.author | DIAZ, Ricardo Sobhie | - |
dc.date.accessioned | 2016-02-11T14:04:22Z | - |
dc.date.available | 2016-02-11T14:04:22Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | PLOS ONE, v.10, n.11, article ID e0142638, 8p, 2015 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/12617 | - |
dc.description.abstract | Objective To examine the feasibility of identifying HIV negative at risk individuals in HIV serodiscordant couples, during voluntary HIV testing in South Brazil. Methods We surveyed HIV testers at 4 public testing sites in Rio Grande do Sul. We obtained information on risk behaviors and sexual partnerships. HIV testing and testing for recent infection were performed; HIV prevalence and risk behaviors were assessed among subjects who reported having a steady partner who was HIV positive (serodiscordant group) and compared with the general testing population. Results Among 3100 patients, 490 (15.8%) reported being in a steady relationship with an HIV positive partner. New HIV infections were diagnosed in 23% of the serodiscordant group (vs. 13% in the general population, p = 0.01); among newly positive subjects, recent HIV infections were more frequent (23/86, 26.7%) among testers with positive partners than among the general testing group (52/334; 15.6%; p = 0.016). Less than half of the serodiscordant testers reported having used a condom during the last sexual intercourse with their HIV-positive partner. Participants with inconsistent condom use with steady partner were four times more likely to test positive for HIV compared to those who reported always using condoms with the steady partner (OR: 4.2; 95% CI: 2.3 to 7.5). Conclusion It is highly feasible to identify large numbers of HIV susceptible individuals who are in HIV serodiscordant relationships in South Brazil testing sites. Condom use within HIV serodiscordant couples is low in this setting, suggesting urgent need for biomedical prevention strategies to reduce HIV transmission. | - |
dc.description.sponsorship | National Institutes of Health [R01 MH0686, P01 AI071713, R03 AI064037] | - |
dc.description.sponsorship | STD/Aids Department [AB/BRA/03/H34 (TC 281/07)] | - |
dc.description.sponsorship | United Nations Office on Drugs and Crime (UNODC) [AB/BRA/03/H34 (TC 281/07)] | - |
dc.language.iso | eng | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.relation.ispartof | Plos One | - |
dc.rights | openAccess | - |
dc.subject.other | discordant couples | - |
dc.subject.other | transmission | - |
dc.subject.other | prevention | - |
dc.subject.other | infection | - |
dc.title | Efficient Identification of HIV Serodiscordant Couples by Existing HIV Testing Programs in South Brazil | - |
dc.type | article | - |
dc.rights.holder | Copyright PUBLIC LIBRARY SCIENCE | - |
dc.identifier.doi | 10.1371/journal.pone.0142638 | - |
dc.identifier.pmid | 26562436 | - |
dc.subject.wos | Multidisciplinary Sciences | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | PILCHER, Christopher D.:Univ Calif San Francisco, Dept Med, Div HIV Infect Dis & Global Med, San Francisco, CA 94143 USA | - |
hcfmusp.author.external | BISOL, Claudia Alquati:Univ Caxias Sul, Ctr Ciencias Biol & Saude, Lab Pesquisa HIV AIDS, Caxias Do Sul, Brazil | - |
hcfmusp.author.external | PAGANELLA, Machline Paim:Univ Caxias Sul, Ctr Ciencias Biol & Saude, Lab Pesquisa HIV AIDS, Caxias Do Sul, Brazil | - |
hcfmusp.author.external | VALLABHANENI, Snigdha:Univ Calif San Francisco, Dept Med, Div HIV Infect Dis & Global Med, San Francisco, CA 94143 USA | - |
hcfmusp.author.external | MOTTA, Leonardo Rapone da:Univ Caxias Sul, Ctr Ciencias Biol & Saude, Lab Pesquisa HIV AIDS, Caxias Do Sul, Brazil | - |
hcfmusp.author.external | KATO, Sergio Kakuta:Univ Caxias Sul, Ctr Ciencias Biol & Saude, Lab Pesquisa HIV AIDS, Caxias Do Sul, Brazil | - |
hcfmusp.author.external | SPERHACKE, Rosa Dea:Univ Caxias Sul, Ctr Ciencias Biol & Saude, Lab Pesquisa HIV AIDS, Caxias Do Sul, Brazil | - |
hcfmusp.author.external | HECHT, Frederick M.:Univ Calif San Francisco, Dept Med, Div HIV Infect Dis & Global Med, San Francisco, CA 94143 USA | - |
hcfmusp.author.external | DIAZ, Ricardo Sobhie:Univ Fed Sao Paulo, Paulista Sch Med, Retrovirl Lab, Sao Paulo, Brazil | - |
hcfmusp.description.articlenumber | e0142638 | - |
hcfmusp.description.issue | 11 | - |
hcfmusp.description.volume | 10 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84955513839 | - |
hcfmusp.origem.id | WOS:000364480900053 | - |
hcfmusp.publisher.city | SAN FRANCISCO | - |
hcfmusp.publisher.country | USA | - |
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dc.description.index | MEDLINE | - |
hcfmusp.citation.scopus | 3 | - |
hcfmusp.scopus.lastupdate | 2024-04-12 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCM Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/60 Artigos e Materiais de Revistas Científicas - ODS/03 Artigos e Materiais de Revistas Científicas - ODS/05 |
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