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https://observatorio.fm.usp.br/handle/OPI/21918| Title: | Efficacy of beta-Lactam/beta-Lactamase Inhibitor Combinations for the Treatment of Bloodstream Infection Due to Extended-Spectrum-beta-Lactamase-Producing Enterobacteriaceae in Hematological Patients with Neutropenia |
| Authors: | GUDIOL, Carlota; ROYO-CEBRECOS, Cristina; ABDALA, Edson; AKOVA, Murat; ALVAREZ, Rocio; CALLE, Guillermo Maestro-de la; CANO, Angela; CERVERA, Carlos; CLEMENTE, Wanessa T.; MARTIN-DAVILA, Pilar; FREIFELD, Alison; GOMEZ, Lucia; GOTTLIEB, Thomas; GURGUI, Merce; HERRERA, Fabian; MANZUR, Adriana; MASCHMEYER, Georg; MEIJE, Yolanda; MONTEJO, Miguel; PEGHIN, Maddalena; RODRIGUEZ-BANO, Jesus; RUIZ-CAMPS, Isabel; SUKIENNIK, Teresa C.; TEBE, Cristian; CARRATALA, Jordi |
| Citation: | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, v.61, n.8, article ID e00164-17, 8p, 2017 |
| Abstract: | beta-Lactam/beta-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum beta-lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem-sparing alternatives for the treatment of BSI due to ESBLs in these patients. |
| Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MIP Artigos e Materiais de Revistas Científicas - LIM/47 |
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| art_GUDIOL_Efficacy_of_betaLactambetaLactamase_Inhibitor_Combinations_for_the_Treatment_2017.PDF Restricted Access | publishedVersion (English) | 572.43 kB | Adobe PDF | View/Open Request a copy |
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