Departamento de Moléstias Infecciosas e Parasitárias - FM/MIP

O Departamento de Moléstias Infecciosas e Parasitárias (MIP), da Faculdade de Medicina da Universidade de São Paulo (FMUSP) tem como objetivo contribuir para a formação de médicos, especialistas, docentes e pesquisadores; gerar conhecimentos pela pesquisa e estender serviços à comunidade. Oferece seis disciplinas nucleares: Microbiologia Médica, Parasitologia, Imunologia Médica, Patologia de Moléstias Transmissíveis, Clínica de Moléstias Transmissíveis, Bases do Controle e Prevenção de Moléstias Transmissíveis, além de outras treze disciplinas optativas capazes de dar uma visão mais ampla a respeito dessa área de estudo.

Oferece aos estudantes bases para a compreensão da relação saúde/moléstia/comunidade para colocá-los em contato com a realidade médica brasileira, no que diz respeito às moléstias transmissíveis. Oferece Pós-graduação lato sensu e stricto sensu, desenvolvendo pesquisa em linhas relacionadas às áreas de Infecção por HIV/AIDS, hepatites, infecções endêmicas, infecções hospitalares e infecções em imunodeprimidos, terapia intensiva, imunizações, acidentes causados por animais peçonhentos e infecções virais. O Programa de Residência Médica/Pós graduação lato sensu em infectologia do Hospital das Clínicas da FMUSP teve início em 1951 tendo formado dezenas de médicos residentes, muitos dos quais desenvolvem suas atividades em vários Estados brasileiros.

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Recent Submissions

  1. Human astrovirus types 1, 4 and 5 circulating among children with acute gastroenteritis in a rural Brazilian state, 2010-2016

    ARCHIVES OF VIROLOGY, v.166, n.11, p.3165-3172, 2021

    This study combined conventional epidemiology of human astroviruses. From 2010 to 2016, 232 stool samples from children under 5 years of age were screened using NGS and conventional RT-PCR followed by genetic analysis in order to investigate the genotypic diversity of classical human astrovirus (...

  2. Evaluation of loop-mediated isothermal amplification assay for detection of Clostridioides difficile infection: A prospective diagnostic performance study

    ANAEROBE, v.71, article ID 102410, 4p, 2021

    A novel Loop-mediated isothermal amplification (LAMP) assay, HiberGene's CD was evaluated with 82 unformed stools from patients suspected of C. difficile infection (CDI). Compared to glutamate dehy-drogenase (GDH) toxins A/B test (C.diff Quik Chek (R)), HiberGene's LAMP showed 100% of sensitivity...

  3. Quantification of airborne SARS-CoV-2 genomic particles in different hospital settings

    SCIENTIFIC REPORTS, v.11, n.1, article ID 21284, 6p, 2021

    We quantified the presence of SARS-CoV-2 RNA in the air of different hospital settings and the autopsy room of the largest medical centre in Sao Paulo, Brazil. Real-time reverse-transcription PCR was used to determine the presence of the envelope protein of SARS-CoV-2 and the nucleocapsid protein...

  4. Diagnosis of human strongyloidiasis: Application in clinical practice

    ACTA TROPICA, v.223, article ID 106081, 8p, 2021

    This review considers the advantages and disadvantages of parasitological techniques, methods of detecting antibodies and antigens, as well as molecular biology techniques in the diagnosis of human strongyloidiasis. In addition, it elucidates the potential of different techniques for rapid and ef...

  5. Evaluation of targets for Strongyloides genus specific molecular diagnosis in experimental strongyloidiasis

    EXPERIMENTAL PARASITOLOGY, v.230, article ID 108157, 6p, 2021

    Strongyloides venezuelensis has been used in different experimental studies, such as those aimed at the evaluation of diagnostic techniques for human strongyloidiasis, mainly the molecular diagnosis. In this study, three regions (genus, 18S and 28S targets) of Strongyloides ribosomal DNA were eva...

  6. Toxocara DNA amplification in serum and tissue samples in BALB/c mice

    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, v.246, article ID 111429, 4p, 2021

    Toxocariasis is still a neglected parasitic disease worldwide and much about its biology and diagnosis has yet to be understood. The migration of third stage larvae via bloodstream suggests a potential use of molecular tools in diagnosis as well to deepen the knowledge about its migration behavio...

  7. Serological screening for Chagas disease in an endemic region of Northern Minas Gerais, Brazil: the SaMi-Trop project


    Chagas disease (CD) is still a neglected disease. Infected individuals are diagnosed late, being treated in worse clinical conditions. Thus, this study aimed to analyze the prevalence and the factors associated with new confirmed cases of CD identified by serological screening in an endemic regio...

  8. Clusters of SARS-CoV-2 Lineage B.1.1.7 Infection after Vaccination with Adenovirus-Vectored and Inactivated Vaccines

    VIRUSES-BASEL, v.13, n.11, article ID 2127, 13p, 2021

    A SARS-CoV-2 B.1.1.7 variant of concern (VOC) has been associated with increased transmissibility, hospitalization, and mortality. This study aimed to explore the factors associated with B.1.1.7 VOC infection in the context of vaccination. On March 2021, we detected SARS-CoV-2 RNA in nasopharynge...

  9. Use of medical face masks versus particulate respirators as a component of personal protective equipment for health care workers in the context of the COVID-19 pandemic


    Currently available evidence supports that the predominant route of human-to-human transmission of the SARS-CoV-2 is through respiratory droplets and/or contact routes. The report by the World Health Organization (WHO) Joint Mission on Coronavirus Disease 2019 (COVID-19) in China supports person-...

  10. Implications of a highly divergent dengue virus strain for cross-neutralization protection, and vaccine immunity

    CELL HOST & MICROBE, v.29, n.11, p.1634-+, 2021

    Although divergent dengue viruses (DENVs) have been isolated in insects, nonhuman primates, and humans, their relationships to the four canonical serotypes (DENV 1-4) are poorly understood. One virus isolated from a dengue patient, DKE-121, falls between genotype and serotype levels of sequence d...