Is there a cure for systemic lupus erythematosus?

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art_SEGURO_Is_there_a_cure_for_systemic_lupus_erythematosus_2013.PDF (105.01 KB)
Citações na Scopus
10
Tipo de produção
article
Data de publicação
2013
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SAGE PUBLICATIONS LTD
Autores
ROSARIO, C.
VASCONCELOS, C.
SHOENFELD, Y.
Citação
LUPUS, v.22, n.5, p.417-421, 2013
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
The morbidity and mortality of systemic lupus erythematosus (SLE) is a subject of intense relevance in the literature, yet descriptions of prolonged and sustained remissions or even cure are barely reported. In recent decades the life expectancy in SLE patients has improved, but the quality of life seems to be poor compared with other chronic diseases and with the general population. The immunopathogenesis of SLE is complex and not fully understood, so patients have been treated with nonspecific immunosuppressive therapies. But in recent years, because of advances in basic science, targeted therapies have been developed. Despite the progress made in treating SLE, currently a cure in SLE seems to be a myth. SLE it seems, remains incurable. A specific treatment has not emerged to directly abrogate a disease-specific autoimmune response. Relapsing manifestations and complications of treatment still remain important markers of morbidity. Lupus (2013) 22, 417-421.
Palavras-chave
Systemic lupus erythematosus, cure, sustained remission, prolonged remission
URI
https://observatorio.fm.usp.br/handle/OPI/2234
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Coleções
Artigos e Materiais de Revistas Científicas - FM/Outros