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https://observatorio.fm.usp.br/handle/OPI/2612| Título: | Analysis of Transmitted Resistance to Raltegravir and Selective Pressure among HIV-1-Infected Patients on a Failing HAART in Sao Paulo, Brazil |
| Autor: | MANTOVANI, N. P.; AZEVEDO, R. G.; RABELATO, J. T.; SANABANI, S.; DIAZ, R. S.; KOMNINAKIS, S. V. |
| Citación: | JOURNAL OF CLINICAL MICROBIOLOGY, v.50, n.6, p.2122-2125, 2012 |
| Resumen: | We studied the presence of primary resistance to raltegravir (RAL), natural polymorphisms, and selection pressure on HIV-1 integrase. We found a high frequency of integrase polymorphisms related to the resistance to RAL and sequence stability. Further studies are needed to determine the importance of these polymorphisms to RAL resistance. |
| Aparece en las colecciones: | Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/52 |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| art_SANABANI_Analysis_of_Transmitted_Resistance_to_Raltegravir_and_Selective_2012.PDF Restricted Access | publishedVersion (English) | 2.08 MB | Adobe PDF | Visualizar/Abrir Request a copy |
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