Socket Reconstruction With Bleomycin, Gentamicin, and Gelatin Sponges Following Eyelid-Sparing Orbital Exenteration for a Colobomatous Macrocyst in an Infant

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art_MICHELSON_Socket_Reconstruction_With_Bleomycin_Gentamicin_and_Gelatin_Sponges_2018.PDF (375.69 KB)
Citações na Scopus
1
Tipo de produção
article
Data de publicação
2018
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
LIPPINCOTT WILLIAMS & WILKINS
Autores
MICHELSON, Sarah J.
ELNER, Victor M.
KAHANA, Alon
Citação
OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, v.34, n.6, p.E201-E203, 2018
Projetos de Pesquisa
Unidades Organizacionais
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Resumo
Microphthalmia is defined by a globe axial length greater than or equal to 2 standard deviations below the age-adjusted mean and can occur as part of a broader syndrome. The presence of a colobomatous cyst with microphthalmia signifies failure of the embryonic neuroectodermal fissure to close appropriately during development of the globe, creating a protuberant globular appendage that inhibits normal growth and development of the eye itself. Cystic reaccumulation of fluid is common after aspiration or surgical removal. Here, the authors describe a case of a young boy with a colobomatous cyst who underwent eyelid-sparing orbital exenteration followed by reconstruction with absorbable gelatin sponge (Gelfoam, Pfizer, Inc.) and the chemotherapeutic agent bleomycin to promote scarring, achieving the equivalent of a biointegrated implant and facilitating satisfactory placement of an ocular prosthesis. A 2-year follow-up MRI revealed adequate volume in the posterior orbit.
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URI
https://observatorio.fm.usp.br/handle/OPI/30165
Referências
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Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC