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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | CRAJOINAS, Renato O. | - |
dc.contributor.author | POLIDORO, Juliano Z. | - |
dc.contributor.author | GIRARDI, Adriana C. C. | - |
dc.date.accessioned | 2019-06-26T17:28:19Z | - |
dc.date.available | 2019-06-26T17:28:19Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v.316, n.5, p.F986-F992, 2019 | - |
dc.identifier.issn | 1931-857X | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/32434 | - |
dc.description.abstract | Isoform 3 of the Na+/H+ exchanger (NHE3) is responsible for the majority of the reabsorption of NaCl, NaHCO3, and. consequently, water in the renal proximal tubule. As such, this transporter plays an essential role in acid-base balance and extracellular fluid volume homeostasis and determining systemic arterial blood pressure levels. NHE3 activity is modulated by a number of mechanisms, including the redistribution of the transporter between the body of the microvilli (where NHE3 is active) and the base of the microvilli (where NHE3 is less active). Although the physiological. pathophysiological, and pharmacological importance of the subcellular distribution of NHE3 has been well established, the exact mechanism whereby NHE3 is translocated along microvilli micmdomains of the proximal tubule apical membrane is unknown. Nonmuscle myosin IIA and unconventional myosin VI move cargoes in anterograde and retrograde directions, respectively, and are known to redistribute along with NHE3 in the proximal tubule in response to a variety of natriuretic and antinatriuretic stimuli, including stimulation or inhibition of the renin-angiotensin system, high dietary Na+ intake, and high blood pressure. Therefore. this review aims to discuss the current evidence that suggests a potential role of myosin IIA and myosin VI in mediating the subcellular distribution of NHE3 along the kidney proximal tubule microvilli and their possible contribution in modifying NHE3-mediated Na+ reabsorption under both physiological and pathophysiological conditions. | eng |
dc.description.sponsorship | Sao Paulo Research Foundation [2016/22140-7] | - |
dc.language.iso | eng | - |
dc.publisher | AMER PHYSIOLOGICAL SOC | eng |
dc.relation.ispartof | American Journal of Physiology-Renal Physiology | - |
dc.rights | restrictedAccess | eng |
dc.subject | extracellular volume homeostasis | eng |
dc.subject | myosin IIA | eng |
dc.subject | myosin VI | eng |
dc.subject | sodium reabsorption | eng |
dc.subject.other | na+/h+ exchanger nhe3 | eng |
dc.subject.other | heavy-chain iia | eng |
dc.subject.other | angiotensin-ii | eng |
dc.subject.other | apical membrane | eng |
dc.subject.other | sodium transporters | eng |
dc.subject.other | gender-differences | eng |
dc.subject.other | nephron function | eng |
dc.subject.other | blood-pressure | eng |
dc.subject.other | mice lacking | eng |
dc.subject.other | kinase-a | eng |
dc.title | The potential role of myosin motor proteins in mediating the subcellular distribution of NHE3 in the renal proximal tubule | eng |
dc.type | article | eng |
dc.rights.holder | Copyright AMER PHYSIOLOGICAL SOC | eng |
dc.identifier.doi | 10.1152/ajprenal.00577.2018 | - |
dc.identifier.pmid | 30864843 | - |
dc.subject.wos | Physiology | eng |
dc.subject.wos | Urology & Nephrology | eng |
dc.type.category | review | eng |
dc.type.version | publishedVersion | eng |
hcfmusp.description.beginpage | F986 | - |
hcfmusp.description.endpage | F992 | - |
hcfmusp.description.issue | 5 | - |
hcfmusp.description.volume | 316 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | WOS:000468323700004 | - |
hcfmusp.origem.id | 2-s2.0-85065770953 | - |
hcfmusp.publisher.city | BETHESDA | eng |
hcfmusp.publisher.country | USA | eng |
hcfmusp.relation.reference | Arrondel C, 2002, J AM SOC NEPHROL, V13, P65 | eng |
hcfmusp.relation.reference | Berg JS, 2001, MOL BIOL CELL, V12, P780, DOI 10.1091/mbc.12.4.780 | eng |
hcfmusp.relation.reference | BIEMESDERFER D, 1993, AM J PHYSIOL, V265, pF736 | eng |
hcfmusp.relation.reference | Biemesderfer D, 2001, J BIOL CHEM, V276, P10161, DOI 10.1074/jbc.M008098200 | eng |
hcfmusp.relation.reference | Biemesderfer D, 1997, AM J PHYSIOL-RENAL, V273, pF289 | eng |
hcfmusp.relation.reference | Biemesderfer D, 1999, J BIOL CHEM, V274, P17518, DOI 10.1074/jbc.274.25.17518 | eng |
hcfmusp.relation.reference | Blaine J, 2009, AM J PHYSIOL-CELL PH, V297, pC1339, DOI 10.1152/ajpcell.00260.2009 | eng |
hcfmusp.relation.reference | Bobulescu IA, 2006, SEMIN NEPHROL, V26, P334, DOI 10.1016/j.semnephrol.2006.07.001 | eng |
hcfmusp.relation.reference | Brasen JC, 2014, AM J PHYSIOL-RENAL, V307, pF1249, DOI 10.1152/ajprenal.00174.2014 | eng |
hcfmusp.relation.reference | de Morais CPC, 2015, AM J PHYSIOL-CELL PH, V309, pC541, DOI 10.1152/ajpcell.00072.2015 | eng |
hcfmusp.relation.reference | Carraro-Lacroix LR, 2009, AM J PHYSIOL-RENAL, V297, pF1647, DOI 10.1152/ajprenal.00082.2009 | eng |
hcfmusp.relation.reference | Chan W, 2005, J BIOL CHEM, V280, P23741, DOI 10.1074/jbc.M5027200 | eng |
hcfmusp.relation.reference | Chen TE, 2014, J CELL SCI, V127, P3535, DOI 10.1242/jcs.149930 | eng |
hcfmusp.relation.reference | Girardi ACC, 2008, AM J PHYSIOL-RENAL, V294, pF414, DOI 10.1152/ajprenal.00174.2007 | eng |
hcfmusp.relation.reference | Crajoinas RO, 2014, ACTA PHYSIOL, V211, P395, DOI 10.1111/apha.12288 | eng |
hcfmusp.relation.reference | Crajoinas RO, 2016, AM J PHYSIOL-CELL PH, V311, pC768, DOI 10.1152/ajpcell.00191.2016 | eng |
hcfmusp.relation.reference | Crajoinas RO, 2010, AM J PHYSIOL-RENAL, V299, pF872, DOI 10.1152/ajprenal.00654.2009 | eng |
hcfmusp.relation.reference | Crajoinas RO, 2018, FASEB J S | eng |
hcfmusp.relation.reference | D'Apolito M, 2002, GENE, V286, P215, DOI 10.1016/S0378-1119(02)00455-9 | eng |
hcfmusp.relation.reference | Donowitz M, 2007, PHYSIOL REV, V87, P825, DOI 10.1152/physrev.00030.2006 | eng |
hcfmusp.relation.reference | ELLISON KE, 1989, J CLIN INVEST, V83, P1941, DOI 10.1172/JCI114102 | eng |
hcfmusp.relation.reference | Farah LXS, 2016, AM J PHYSIOL-RENAL, V310, pF123, DOI 10.1152/ajprenal.00394.2015 | eng |
hcfmusp.relation.reference | Girardi AC, 2005, FASEB J, V19, pA140 | eng |
hcfmusp.relation.reference | Girardi ACC, 2000, KIDNEY INT, V58, P1623, DOI 10.1046/j.1523-1755.2000.00323.x | eng |
hcfmusp.relation.reference | Girardi ACC, 2012, AM J PHYSIOL-CELL PH, V302, pC1569, DOI 10.1152/ajpcell.00017.2012 | eng |
hcfmusp.relation.reference | GOOD DW, 1984, J CLIN INVEST, V73, P602, DOI 10.1172/JCI111250 | eng |
hcfmusp.relation.reference | Gorodeski GI, 2007, ENDOCRINOLOGY, V148, P279, DOI 10.1210/en.2006-1045 | eng |
hcfmusp.relation.reference | Hartman MA, 2011, ANNU REV CELL DEV BI, V27, P133, DOI 10.1146/annurev-cellbio-100809-151502 | eng |
hcfmusp.relation.reference | Honegger KJ, 2006, P NATL ACAD SCI USA, V103, P803, DOI 10.1073/pnas.0503562103 | eng |
hcfmusp.relation.reference | Hosaka K, 2009, KIDNEY INT, V75, P1308, DOI 10.1038/ki.2009.85 | eng |
hcfmusp.relation.reference | Hu MC, 2001, J BIOL CHEM, V276, P26906, DOI 10.1074/jbc.M011338200 | eng |
hcfmusp.relation.reference | Hu MC, 2013, AM J PHYSIOL-RENAL, V304, pF1169, DOI 10.1152/ajprenal.00630.2012 | eng |
hcfmusp.relation.reference | Jones DW, 2004, HYPERTENSION, V43, P1, DOI 10.1161/01.HYP.0000110061.06674.ca | eng |
hcfmusp.relation.reference | Kandasamy RA, 1996, J BIOL CHEM, V271, P10551, DOI 10.1074/jbc.271.18.10551 | eng |
hcfmusp.relation.reference | Kocinsky HS, 2007, AM J PHYSIOL-RENAL, V293, pF212, DOI 10.1152/ajprenal.00042.2007 | eng |
hcfmusp.relation.reference | Kocinsky HS, 2005, AM J PHYSIOL-RENAL, V289, pF249, DOI 10.1152/ajprenal.00082.2004 | eng |
hcfmusp.relation.reference | Kovacs M, 2003, J BIOL CHEM, V278, P38132, DOI 10.1074/jbc.M305453200 | eng |
hcfmusp.relation.reference | Krendel M, 2005, PHYSIOLOGY, V20, P239, DOI 10.1152/physiol.00014.2005 | eng |
hcfmusp.relation.reference | Kurashima K, 1997, J BIOL CHEM, V272, P28672, DOI 10.1074/jbc.272.45.28672 | eng |
hcfmusp.relation.reference | Lanzano L, 2011, AM J PHYSIOL-CELL PH, V301, pC850, DOI 10.1152/ajpcell.00412.2010 | eng |
hcfmusp.relation.reference | Ledoussal C, 2001, AM J PHYSIOL-RENAL, V281, pF718 | eng |
hcfmusp.relation.reference | Leong PKK, 2006, AM J PHYSIOL-RENAL, V290, pF854, DOI 10.1152/ajprenal.00353.2005 | eng |
hcfmusp.relation.reference | Leong PKK, 2004, AM J PHYSIOL-REG I, V287, pR878, DOI 10.1152/ajpregu.00180.2004 | eng |
hcfmusp.relation.reference | Li XC, 2018, HYPERTENSION, V72, P1328, DOI 10.1161/HYPERTENSIONAHA.118.10884 | eng |
hcfmusp.relation.reference | Li X, 2006, ENDOCRINOLOGY, V147, P5236, DOI 10.1210/en.2006-0779 | eng |
hcfmusp.relation.reference | Lorenz JN, 1999, AM J PHYSIOL-RENAL, V277, pF447 | eng |
hcfmusp.relation.reference | Luchi W, 2015, FASEB J, V29 | eng |
hcfmusp.relation.reference | Magyar CE, 2000, AM J PHYSIOL-RENAL, V279, pF358 | eng |
hcfmusp.relation.reference | Maunsbach AB, 2000, J AM SOC NEPHROL, V11, P2179 | eng |
hcfmusp.relation.reference | McDonough AA, 2003, CURR OPIN NEPHROL HY, V12, P533, DOI 10.1097/01.mnh.0000088733.87142.0a | eng |
hcfmusp.relation.reference | McDonough AA, 2016, KIDNEY INT REP, V1, P166, DOI 10.1016/j.ekir.2016.06.008 | eng |
hcfmusp.relation.reference | Mirabito KM, 2014, AM J PHYSIOL-RENAL, V307, pF901, DOI 10.1152/ajprenal.00288.2014 | eng |
hcfmusp.relation.reference | Otterpohl KL, 2017, PHYSIOL REP, V5, DOI 10.14814/phy2.13513 | eng |
hcfmusp.relation.reference | OUDAR O, 1991, RENAL PHYSIOL BIOCH, V14, P92 | eng |
hcfmusp.relation.reference | Pontes RB, 2015, AUTON NEUROSCI BAS C, V192, P94 | eng |
hcfmusp.relation.reference | Pontes RB, 2015, AM J PHYSIOL-RENAL, V308, pF848, DOI 10.1152/ajprenal.00515.2014 | eng |
hcfmusp.relation.reference | Quan A, 2004, AM J PHYSIOL-RENAL, V287, pF452, DOI 10.1152/ajprenal.00188.2003 | eng |
hcfmusp.relation.reference | Queiroz-Leite GD, 2011, BIOCHEM BIOPH RES CO, V409, P470, DOI 10.1016/j.bbrc.2011.05.028 | eng |
hcfmusp.relation.reference | Quigley R, 2008, GENDER MED, V5, pS114, DOI 10.1016/j.genm.2008.03.011 | eng |
hcfmusp.relation.reference | Reckelhoff JF, 2018, CURR OPIN NEPHROL HY, V27, P176, DOI 10.1097/MNH.0000000000000404 | eng |
hcfmusp.relation.reference | Reckelhoff JF, 2001, HYPERTENSION, V37, P1199, DOI 10.1161/01.HYP.37.5.1199 | eng |
hcfmusp.relation.reference | Rey M, 2007, J CELL SCI, V120, P1126, DOI 10.1242/jcs.03415 | eng |
hcfmusp.relation.reference | Riquier-Brison ADM, 2010, AM J PHYSIOL-RENAL, V298, pF177, DOI 10.1152/ajprenal.00464.2009 | eng |
hcfmusp.relation.reference | RODMAN JS, 1986, J CELL BIOL, V102, P77, DOI 10.1083/jcb.102.1.77 | eng |
hcfmusp.relation.reference | Sabolic I, 2007, PFLUG ARCH EUR J PHY, V455, P397, DOI 10.1007/s00424-007-0308-1 | eng |
hcfmusp.relation.reference | Sandberg K, 2012, BIOL SEX DIFFER, V3, DOI 10.1186/2042-6410-3-7 | eng |
hcfmusp.relation.reference | Schultheis PJ, 1998, NAT GENET, V19, P282 | eng |
hcfmusp.relation.reference | Sekine T, 2010, KIDNEY INT, V78, P207, DOI 10.1038/ki.2010.21 | eng |
hcfmusp.relation.reference | Shimoura CG, 2015, AUTON NEUROSCI BAS C, V192, P116 | eng |
hcfmusp.relation.reference | Steimle PA, 2005, BIOCHEM BIOPH RES CO, V331, P1560, DOI 10.1016/j.bbrc.2005.04.082 | eng |
hcfmusp.relation.reference | Vallon V, 2000, AM J PHYSIOL-RENAL, V278, pF375 | eng |
hcfmusp.relation.reference | VANCE BA, 1989, J MEMBRANE BIOL, V108, P53, DOI 10.1007/BF01870425 | eng |
hcfmusp.relation.reference | Veiras LC, 2017, J AM SOC NEPHROL, V28, P3504, DOI 10.1681/ASN.2017030295 | eng |
hcfmusp.relation.reference | Walmsley SJ, 2012, AM J PHYSIOL-RENAL, V302, pF1465, DOI 10.1152/ajprenal.00390.2011 | eng |
hcfmusp.relation.reference | Walmsley SJ, 2010, AM J PHYSIOL-RENAL, V298, pF1323, DOI 10.1152/ajprenal.00711.2009 | eng |
hcfmusp.relation.reference | Wang DS, 2005, AM J PHYSIOL-CELL PH, V289, pC802, DOI 10.1152/ajpcell.00597.2004 | eng |
hcfmusp.relation.reference | Wang L, 2017, HYPERTENSION, V70, P1219, DOI 10.1161/HYPERTENSIONAHA.117.10052 | eng |
hcfmusp.relation.reference | Wells AL, 1999, NATURE, V401, P505, DOI 10.1038/46835 | eng |
hcfmusp.relation.reference | Yang LE, 2005, J AM SOC NEPHROL, V16, P2890, DOI 10.1681/ASN.2005040366 | eng |
hcfmusp.relation.reference | Yang LE, 2004, AM J PHYSIOL-RENAL, V287, pF896, DOI 10.1152/ajprenal.00160.2004 | eng |
hcfmusp.relation.reference | Yang LE, 2003, AM J PHYSIOL-RENAL, V284, pF1056, DOI 10.1152/ajprenal.00317.2002 | eng |
hcfmusp.relation.reference | Yang LE, 2003, AM J PHYSIOL-RENAL, V284, pF313, DOI 10.1152/ajprenal.00134.2002 | eng |
hcfmusp.relation.reference | Yang LE, 2008, AM J PHYSIOL-RENAL, V295, pF1003, DOI 10.1152/ajprenal.90235.2008 | eng |
hcfmusp.relation.reference | Yang LE, 2007, AM J PHYSIOL-RENAL, V293, pF1197, DOI 10.1152/ajprenal.00040.2007 | eng |
hcfmusp.relation.reference | YIP KP, 1998, AM J PHYSIOL-RENAL, V275, pF56, DOI 10.1152/AJPRENAL.1998.275.4.F565 | eng |
hcfmusp.relation.reference | Yun CHC, 1997, P NATL ACAD SCI USA, V94, P3010, DOI 10.1073/pnas.94.7.3010 | eng |
hcfmusp.relation.reference | Zhang YB, 1996, AM J PHYSIOL-RENAL, V270, pF1004 | eng |
hcfmusp.relation.reference | Zhang YB, 1999, AM J PHYSIOL-RENAL, V276, pF711 | eng |
hcfmusp.relation.reference | Zhao H, 1999, J BIOL CHEM, V274, P3978, DOI 10.1074/jbc.274.7.3978 | eng |
hcfmusp.relation.reference | 1998, J BIOL CHEM, V273, P2585, DOI 10.1074/JBC.273.40.25856 | eng |
hcfmusp.relation.reference | 2001, J BIOL CHEM, V276, P4667, DOI 10.1074/JBC.M106897200 | eng |
hcfmusp.relation.reference | 1995, J CLIN INVEST, V95, P2143, DOI 10.1172/JCI117903 | eng |
hcfmusp.relation.reference | 2014, ACTA PHYSL OXF, V210, P678, DOI 10.1111/APHA.12181 | eng |
dc.description.index | MEDLINE | eng |
dc.identifier.eissn | 1522-1466 | - |
hcfmusp.citation.scopus | 0 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
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