Vasopressors during adult cardiac arrest: A systematic review and meta-analysis

Imagem de Miniatura
Arquivos
art_HOLMBERG_Vasopressors_during_adult_cardiac_arrest_A_systematic_review_2019.PDF (3.37 MB)
Citações na Scopus
76
Tipo de produção
article
Data de publicação
2019
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER IRELAND LTD
Autores
HOLMBERG, Mathias J.
ISSA, Mahmoud S.
MOSKOWITZ, Ari
MORLEY, Peter
WELSFORD, Michelle
NEUMAR, Robert W.
COKER, Amin
HANSEN, Christopher K.
ANDERSEN, Lars W.
Citação
RESUSCITATION, v.139, p.106-121, 2019
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Aim: To systematically review the literature on the use of vasopressors during adult cardiac arrest to inform an update of international guidelines. Methods: PRISMA guidelines were followed. We searched Medline, Embase, Web of Science, CINAHL, and the Cochrane Library for controlled trials and observational studies. The population included adults with cardiac arrest in any setting. Pairs of investigators reviewed studies for relevance, extracted data, and assessed the risk of bias for individual studies. Certainty of evidence was evaluated using GRADE for controlled trials and meta-analyses were performed when at least two studies could be pooled. Results: We included 15 controlled trials and 67 observational studies. The majority of studies included out-of-hospital cardiac arrest only. Meta-analyses were performed for two controlled trials comparing epinephrine to placebo, three comparing vasopressin to epinephrine, and three comparing epinephrine plus vasopressin to epinephrine only. All controlled trials ranged between low to some concern in risk of bias. The certainty of evidence ranged from very low to high. Risk of bias for observational studies was generally critical or serious, largely due to confounding and selection bias. Conclusions: Controlled trial data suggest that epinephrine improves return of spontaneous circulation, survival to hospital discharge, and 3-month survival in out-of-hospital cardiac arrest. The improvement in short-term outcomes appeared more pronounced for non-shockable rhythms. Differences in long-term neurological outcome did not reach statistical significance, although there was a signal toward improved outcomes. Controlled trial data indicated no benefit from vasopressin with or without epinephrine compared to epinephrine only.
Palavras-chave
ILCOR, Vasopressor, Epinephrine, Cardiac arrest, Advanced life support, Systematic review, Meta-analysis
URI
https://observatorio.fm.usp.br/handle/OPI/32571
Referências
  1. Andersen LW, 2019, JAMA-J AM MED ASSOC, V321, P1200, DOI 10.1001/jama.2019.1696
  2. Andersen LW, 2018, RESUSCITATION, V125, P79, DOI 10.1016/j.resuscitation.2018.02.006
  3. Andersen LW, 2016, BMJ-BRIT MED J, V353, pi1577, DOI 10.1136/BMJ.I1577
  4. Arrich J, 2009, RESUSCITATION, V80, P876, DOI 10.1016/j.resuscitation.2009.04.045
  5. Benjamin EJ, 2019, CIRCULATION
  6. BEURET P, 1993, RESUSCITATION, V25, P171, DOI 10.1016/0300-9572(93)90093-6
  7. BROWN CG, 1992, NEW ENGL J MED, V327, P1051, DOI 10.1056/NEJM199210083271503
  8. Bunch TJ, 2004, CARDIOLOGY, V102, P41, DOI 10.1159/000077003
  9. Callaham M, 1996, ANN EMERG MED, V27, P638, DOI 10.1016/S0196-0644(96)70169-5
  10. CALLAHAM M, 1992, JAMA-J AM MED ASSOC, V268, P2667, DOI 10.1001/jama.268.19.2667
  11. Callaway CW, 2006, AM J CARDIOL, V98, P1316, DOI 10.1016/j.amjcard.2006.06.022
  12. Callaway CW, 2015, CIRCULATION, V132, pS84, DOI 10.1161/CIR.0000000000000273
  13. Cantrell CL, 2013, PREHOSP EMERG CARE, V17, P15, DOI 10.3109/10903127.2012.702193
  14. Chan PS, 2012, ARCH INTERN MED, V172, P947, DOI 10.1001/archinternmed.2012.2050
  15. Chen CT, 2016, J CHIN MED ASSOC, V79, P11, DOI 10.1016/j.jcma.2015.07.011
  16. Chiang WC, 2015, SCAND J TRAUMA RESUS, V23, DOI 10.1186/s13049-015-0181-4
  17. CHOUX C, 1995, RESUSCITATION, V29, P3, DOI 10.1016/0300-9572(94)00810-3
  18. Cody P, 2010, PREHOSP DISASTER MED, V25, P420, DOI 10.1017/S1049023X00008499
  19. Crile GW, 1903, ST LOUIS MED SURG J, V84, P299
  20. Crile GW, 1903, CLEVE MED J, V2
  21. de-la-Chica R, 2010, MED INTENSIVA, V34, P161, DOI 10.1016/j.medin.2009.11.003
  22. Donnino MW, 2014, BMJ-BRIT MED J, V348, DOI 10.1136/bmj.g3028
  23. Ducros L, 2011, J EMERG MED, V41, P453, DOI 10.1016/j.jemermed.2010.02.030
  24. Dumas F, 2014, J AM COLL CARDIOL, V64, P2360, DOI 10.1016/j.jacc.2014.09.036
  25. Ewy GA, 2015, RESUSCITATION, V96, P180, DOI 10.1016/j.resuscitation.2015.08.011
  26. Fisk CA, 2018, RESUSCITATION, V124, P43, DOI 10.1016/j.resuscitation.2018.01.004
  27. Fujii T, 2017, BMJ OPEN, V7, DOI 10.1136/bmjopen-2016-015055
  28. Fukuda T, 2016, EUR J CLIN PHARMACOL, V72, P1255, DOI 10.1007/s00228-016-2093-2
  29. Fukuda T, 2016, EUR J INTERN MED, V30, P61, DOI 10.1016/j.ejim.2016.01.022
  30. Fukuda T, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000003107
  31. Fukuda T, 2015, HEART LUNG CIRC, V24, P241, DOI 10.1016/j.hlc.2014.09.004
  32. Fukuda T, 2014, INT J CARDIOL, V176, P910, DOI 10.1016/j.ijcard.2014.08.057
  33. Funada A, 2018, HEART VESSELS, V33, P1525, DOI 10.1007/s00380-018-1205-6
  34. Ghafourian Nasim, 2015, Recent Adv Cardiovasc Drug Discov, V10, P65
  35. Gomes André Mansur de Carvalho Guanaes, 2005, Arq. Bras. Cardiol., V85, P262, DOI 10.1590/S0066-782X2005001700006
  36. Goto Y, 2013, CRIT CARE, V17, DOI 10.1186/cc12872
  37. Graves JR, 1997, RESUSCITATION, V35, P117
  38. Grmec S, 2006, CRIT CARE, V10, DOI 10.1186/cc3967
  39. Gueugniaud PY, 2008, NEW ENGL J MED, V359, P21, DOI 10.1056/NEJMoa0706873
  40. Gueugniaud PY, 1998, NEW ENGL J MED, V339, P1595, DOI 10.1056/NEJM199811263392204
  41. Guyatt GH, 2008, BRIT MED J, V336, P924, DOI 10.1136/bmj.39489.470347.AD
  42. Guyette FX, 2004, RESUSCITATION, V63, P277, DOI 10.1016/j.resuscitation.2004.05.007
  43. Gwinnutt CL, 2000, RESUSCITATION, V47, P125, DOI 10.1016/S0300-9572(00)00212-4
  44. Hagihara A, 2018, AM J EMERG MED, V36, P73, DOI 10.1016/j.ajem.2017.07.018
  45. Hagihara A, 2012, JAMA-J AM MED ASSOC, V307, P1161, DOI 10.1001/jama.2012.294
  46. Hansen M, 2018, CIRCULATION, V137, P2032, DOI 10.1161/CIRCULATIONAHA.117.033067
  47. Hasegawa M, 2015, SCAND J TRAUMA RESUS, V23, DOI 10.1186/s13049-015-0112-4
  48. Hayakawa M, 2013, J INTENSIVE CARE, V1, DOI 10.1186/2052-0492-1-12
  49. Hayashi Y, 2012, CIRC J, V76, P1639, DOI 10.1253/circj.CJ-11-1433
  50. Hazinski MF, 2015, CIRCULATION, V132, pS2, DOI 10.1161/CIR.0000000000000270
  51. HERLITZ J, 1995, RESUSCITATION, V29, P195, DOI 10.1016/0300-9572(94)00851-6
  52. Higgins JPT, COCHRANE METHODS COC, P10
  53. Ho ML, 2018, EMERG MED J, V35, P89, DOI 10.1136/emermed-2017-206878
  54. Holmen J, 2017, RESUSCITATION, V113, P33, DOI 10.1016/j.resuscitation.2017.01.006
  55. Homma Y, 2019, AM J EMERG MED, V37, P241, DOI 10.1016/j.ajem.2018.05.037
  56. Hubble MW, 2017, PREHOSP DISASTER MED, V32, P297, DOI 10.1017/S1049023X17000115
  57. Hubble MW, 2015, PREHOSP EMERG CARE, V19, P457, DOI 10.3109/10903127.2015.1005262
  58. Iqbal MB, 2015, AM J CARDIOL, V115, P730, DOI 10.1016/j.amjcard.2014.12.033
  59. Irfan FB, 2017, INT J CARDIOL, V240, P438, DOI 10.1016/j.ijcard.2017.03.134
  60. Jacobs IG, 2011, RESUSCITATION, V82, P1138, DOI 10.1016/j.resuscitation.2011.06.029
  61. Kim YJ, 2016, RESUSCITATION, V101, P1, DOI 10.1016/j.resuscitation.2016.01.004
  62. Koscik C, 2013, RESUSCITATION, V84, P915, DOI 10.1016/j.resuscitation.2013.03.023
  63. Lai H, 2015, RESUSCITATION, V89, P155, DOI 10.1016/j.resuscitation.2015.01.034
  64. Langhelle A, 2003, RESUSCITATION, V56, P247, DOI 10.1016/S0300-9572(02)00409-4
  65. LINDNER KH, 1991, ACTA ANAESTH SCAND, V35, P253, DOI 10.1111/j.1399-6576.1991.tb03283.x
  66. LINDNER KH, 1991, AM J CARDIOL, V67, P427, DOI 10.1016/0002-9149(91)90055-P
  67. Lindner KH, 1997, LANCET, V349, P535, DOI 10.1016/S0140-6736(97)80087-6
  68. Link MS, 2015, CIRCULATION, V132, pS444, DOI 10.1161/CIR.0000000000000261
  69. LIPMAN J, 1993, ANAESTH INTENS CARE, V21, P192, DOI 10.1177/0310057X9302100210
  70. Macdonald G, 2012, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD001930.pub3
  71. Machida M, 2012, J CARDIOL, V60, P503, DOI 10.1016/j.jjcc.2012.07.001
  72. Mally S, 2007, CRIT CARE, V11, DOI 10.1186/cc5726
  73. Min F, 2016, ZHONGHUA WEI ZHONG B, V28
  74. Monsieurs KG, 2015, RESUSCITATION, V95, P1, DOI 10.1016/j.resuscitation.2015.07.038
  75. Mukoyama T, 2009, RESUSCITATION, V80, P755, DOI 10.1016/j.resuscitation.2009.04.005
  76. Nagao K, 2016, CIRCULATION, V133, P1386, DOI 10.1161/CIRCULATIONAHA.115.018788
  77. Nakahara S, 2013, BMJ-BRIT MED J, V347, DOI 10.1136/bmj.f6829
  78. Nakahara S, 2012, ACAD EMERG MED, V19, P782, DOI 10.1111/j.1553-2712.2012.01387.x
  79. Neset A, 2013, ACTA ANAESTH SCAND, V57, P1260, DOI 10.1111/aas.12184
  80. Nordseth T, 2012, RESUSCITATION, V83, P946, DOI 10.1016/j.resuscitation.2012.02.031
  81. Olasveengen TM, 2012, RESUSCITATION, V83, P327, DOI 10.1016/j.resuscitation.2011.11.011
  82. Olasveengen TM, 2009, JAMA-J AM MED ASSOC, V302, P2222, DOI 10.1001/jama.2009.1729
  83. Ong MEH, 2007, ANN EMERG MED, V50, P635, DOI 10.1016/j.annemergmed.2007.03.028
  84. Ong MEH, 2012, RESUSCITATION, V83, P953, DOI 10.1016/j.resuscitation.2012.02.005
  85. Ono Y, 2015, J INTENSIVE CARE, V3, DOI 10.1186/s40560-015-0094-3
  86. Patel KK, 2018, CIRCULATION, V137, P2041, DOI 10.1161/CIRCULATIONAHA.117.030488
  87. PEARSON JW, 1963, AM HEART J, V66, P210, DOI 10.1016/0002-8703(63)90036-X
  88. Perkins GD, 2018, NEW ENGL J MED, V379, P711, DOI 10.1056/NEJMoa1806842
  89. Perkins GD, 2019, RESUSCITATION
  90. Raina KD, 2015, BIOMED RES INT, DOI 10.1155/2015/283608
  91. Rasmus A, 2004, ANESTEZJOLOGIA INTEN, V36, P185
  92. Reynolds JC, 2016, CIRCULATION, V134, P2084, DOI 10.1161/CIRCULATIONAHA.116.023309
  93. Sagisaka R, 2017, AM J EMERG MED, V35, P1462, DOI 10.1016/j.ajem.2017.04.052
  94. Sherman BW, 1997, PHARMACOTHERAPY, V17, P242
  95. SILFVAST T, 1985, ACTA ANAESTH SCAND, V29, P610, DOI 10.1111/j.1399-6576.1985.tb02265.x
  96. Sterne JAC, 2016, BMJ-BRIT MED J, V355, DOI 10.1136/bmj.i4919
  97. STIELL IG, 1992, NEW ENGL J MED, V327, P1045, DOI 10.1056/NEJM199210083271502
  98. Stiell IG, 2001, LANCET, V358, P105, DOI 10.1016/S0140-6736(01)05328-4
  99. Straznitskas AD, 2015, AM J CRIT CARE, V24, pE22, DOI 10.4037/ajcc2015936
  100. Tanaka H, 2016, AM J EMERG MED, V34, P2284, DOI 10.1016/j.ajem.2016.08.026
  101. Tomio J, 2017, PREHOSP EMERG CARE, V21, P432, DOI 10.1080/10903127.2016.1274347
  102. Tong Julia T, 2016, Crit Care Med, V44, pe1202
  103. Turner DW, 2014, ANN PHARMACOTHER, V48, P986, DOI 10.1177/1060028014537037
  104. Ueta H, 2017, AM J EMERG MED, V35, P676, DOI 10.1016/j.ajem.2016.12.066
  105. Vahdati SS, 2018, ADV BIOSCI CLIN MED, V6
  106. van Walraven C, 1998, ANN EMERG MED, V32, P544, DOI 10.1016/S0196-0644(98)70031-9
  107. Vancini-Campanharo CR, 2015, EINSTEIN-SAO PAULO, V13, P183, DOI 10.1590/S1679-45082015AO3286
  108. Velly L, 2018, LANCET NEUROL, V17, P317, DOI 10.1016/S1474-4422(18)30027-9
  109. Wang HE, 2005, RESUSCITATION, V67, P69, DOI 10.1016/j.resuscitation.2005.05.008
  110. Warren SA, 2014, RESUSCITATION, V85, P350, DOI 10.1016/j.resuscitation.2013.10.004
  111. Wenzel V, 2004, NEW ENGL J MED, V350, P105, DOI 10.1056/NEJMoa025431
  112. Woodhouse SP, 1995, RESUSCITATION, V30, P243, DOI 10.1016/0300-9572(95)00890-X
  113. Yanagawa Y, 2010, J EMERG MED, V38, P340, DOI 10.1016/j.jemermed.2008.04.037
  114. Zhang WW, 2018, RESUSCITATION, V127, P68, DOI 10.1016/j.resuscitation.2018.04.004

Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC