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Title: Spinal Cord Stimulation for Freezing of Gait: From Bench to Bedside
Authors: FONOFF, Erich TalamoniLIMA-PARDINI, Andrea C. DeCOELHO, Daniel BoariMONACO, Bernardo AssumpcaoMACHADO, BirajaraSOUZA, Carolina Pinto deGHILARDI, Maria Gabriela dos SantosHAMANI, Clement
Citation: FRONTIERS IN NEUROLOGY, v.10, article ID 905, 15p, 2019
Abstract: Spinal cord stimulation (SCS) has been used for the treatment of chronic pain for nearly five decades. With a high degree of efficacy and a low incidence of adverse events, it is now considered to be a suitable therapeutic alternative in most guidelines. Experimental studies suggest that SCS may also be used as a therapy for motor and gait dysfunction in parkinsonian states. The most common and disabling gait dysfunction in patients with Parkinson's disease (PD) is freezing of gait (FoG). We review the evolution of SCS for gait disorders from bench to bedside and discuss potential mechanisms of action, neural substrates, and clinical outcomes.
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Artigos e Materiais de Revistas Científicas - FM/MNE
Departamento de Neurologia - FM/MNE

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/IPq
Instituto de Psiquiatria - HC/IPq

Artigos e Materiais de Revistas Científicas - LIM/45
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica

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