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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
dc.contributor.author | SOARES, Lismeia Raimundo | |
dc.contributor.author | MENEZES, Gabriella Coelho | |
dc.contributor.author | BARRETO, Ana Paula Menna | |
dc.contributor.author | SANT'ANNA, Monica de Souza Lima | |
dc.contributor.author | CARDOSO, Nadir Machado Alves | |
dc.contributor.author | CASSEB, Jorge Simao do Rosario | |
dc.contributor.author | FONSECA, Fernando Luiz Affonso | |
dc.date.accessioned | 2020-06-01T14:51:23Z | - |
dc.date.available | 2020-06-01T14:51:23Z | - |
dc.date.issued | 2020 | |
dc.identifier.citation | REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, v.66, n.1, p.67-73, 2020 | |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/35929 | - |
dc.description.abstract | OBJECTIVES: Individuals living with HIV seem to be more prone to changes in the redistribution of body fat, characterized as lipodystrophy, which may occur in conjunction with metabolic diseases. In the present study, such impacts were assessed in adults with and without HIV and associated with the time of virus diagnosis and treatment with antiretroviral. METHODS: A cross-sectional study with 123 adults, in which 87 had HIV and 36 without HIV, of both sexes, in outpatient follow-up at the Specialized Care Service (SAE) in Macae-RJ. The following were made: 1) Alteration in body fat distribution, measured by anthropometric parameters and self-reported lipodystrophy; 2) Biochemical profile; 3) Association between HIV diagnosis time and antiretroviral treatment. RESULTS: 54.47% (n = 67) males, 45.52% (n = 56) females, mean age 37 years. Of these 87 were people living with HIV, 29% (n = 25) had self-reported lipodystrophy, mean time of virus infection, and antiretroviral treatment (5.80 +/- 4.56 and 5.14 +/- 3.82 years), respectively. Patients with self-reported lipodystrophy had a greater change in body fat distribution between 3-6 years of HIV diagnosis and a negative cholesterol profile. The antiretroviral treatment time influenced total cholesterol and triglycerides, even for patients without self-reported lipodystrophy, with a further nine years under treatment. CONCLUSION: In this study, the negative cholesterol profile was mainly related to antiretroviral treatment time, even for patients without self-reported lipodystrophy, and changes in body fat distribution, measured by anthropometry, was especially associated with time for HIV infection in those with lipodystrophy self-reported. | eng |
dc.language.iso | eng | |
dc.publisher | ASSOC MEDICA BRASILEIRA | eng |
dc.relation.ispartof | Revista da Associacao Medica Brasileira | |
dc.rights | openAccess | eng |
dc.subject | Lipodystrophy | eng |
dc.subject | Profile Biochemistry | eng |
dc.subject | HIV | eng |
dc.subject.other | people | eng |
dc.subject.other | therapy | eng |
dc.subject.other | risk | eng |
dc.subject.other | mass | eng |
dc.subject.other | art | eng |
dc.title | Association between changes in body fat distribution, biochemical profile, time of HIV diagnosis, and antiretroviral treatment in adults living with and without virus infection | eng |
dc.type | article | eng |
dc.rights.holder | Copyright ASSOC MEDICA BRASILEIRA | eng |
dc.identifier.doi | 10.1590/1806-9282.66.1.67 | |
dc.identifier.pmid | 32130384 | |
dc.subject.wos | Medicine, General & Internal | eng |
dc.type.category | original article | eng |
dc.type.version | publishedVersion | eng |
hcfmusp.author.external | SOARES, Lismeia Raimundo:UFRJaneiro, Programa Nutr, Dept Nutr, Campus Macae, Macae, RJ, Brazil; FMABC, Santo Andre, SP, Brazil | |
hcfmusp.author.external | MENEZES, Gabriella Coelho:UFRJ, Dept Nutr, Campus Macae, Macae, RJ, Brazil | |
hcfmusp.author.external | BARRETO, Ana Paula Menna:UFRJaneiro, Programa Nutr, Dept Nutr, Campus Macae, Macae, RJ, Brazil | |
hcfmusp.author.external | SANT'ANNA, Monica de Souza Lima:UFRJ, Programa Alimentacao Colet, Dept Nutr, Campus Macae, Macae, RJ, Brazil | |
hcfmusp.author.external | CARDOSO, Nadir Machado Alves:HIV AIDS & Hepatites Virais, Dept Vigilancia Prevencao & Controle IST, Macae, RJ, Brazil | |
hcfmusp.author.external | FONSECA, Fernando Luiz Affonso:Unifesp, Dept Ciencias Farmaceut, Campus Diadema, Diadema, SP, Brazil; FMABC, Programa Posgrad Ciencias Saude, Dept Patol & Analises Clin, Santo Andre, SP, Brazil | |
hcfmusp.description.beginpage | 67 | |
hcfmusp.description.endpage | 73 | |
hcfmusp.description.issue | 1 | |
hcfmusp.description.volume | 66 | |
hcfmusp.origem | WOS | |
hcfmusp.origem.id | WOS:000517996100013 | |
hcfmusp.origem.id | 2-s2.0-85081041692 | |
hcfmusp.origem.id | SCIELO:S0104-42302020000100067 | |
hcfmusp.publisher.city | SAO PAULO | eng |
hcfmusp.publisher.country | BRAZIL | eng |
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dc.description.index | MEDLINE | eng |
dc.identifier.eissn | 1806-9282 | |
hcfmusp.citation.scopus | 2 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MDT Artigos e Materiais de Revistas Científicas - LIM/56 Artigos e Materiais de Revistas Científicas - ODS/03 |
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art_SOARES_Association_between_changes_in_body_fat_distribution_biochemical_2020.PDF | publishedVersion (English) | 158.24 kB | Adobe PDF | View/Open |
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