LIM/35 - Laboratório de Nutrição e Cirurgia Metabólica do Aparelho Digestivo

URI Permanente desta comunidade

https://observatorio.fm.usp.br/handle/OPI/3734
O Laboratório de Nutrição e Cirurgia Metabólica do Aparelho Digestivo é ligado ao Departamento de Gastroenterologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: fisiologia aplicada à digestão; tratamento cirúrgico de câncer de esôfago e cárdia; imunomodulação em cirurgia; mecanismos envolvidos na disfagia alta e reflexo gastroesofágico; anatomia cirúrgica do fígado; transplante do fígado e regeneração hepática; efeitos de dietas e nutrientes, in vitro, sobre comportamento imunológico de células brancas; ciclo celular; apoptose e expressão gênica em linhagens de celular de tumor de mama, e, in vivo, em modelos de queimaduras cutâneas; síndrome do intestino curto; colite experimental; cicatrização de feridas e pancreatite aguda.

Site oficial: http://limhc.fm.usp.br/portal/lim35-laboratorio-de-nutricao-e-cirurgia-metabolica-do-aparelho-digestivo/

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article 0 Citação(ões) na Scopus
Management of a refractory marginal ulcer following Roux-en-Y gastric bypass with EUS-guided Roux-en-Y gastric bypass reversal
(2023) KERBAGE, A.; ANNAN, K. Al; BRUNALDI, V. O.; RAZZAK, F. A.; ABBOUD, D. M.; GALA, K.; GHANEM, O.; DAYYEH, B. K. Abu
article 0 Citação(ões) na Scopus
Endoscopic resection of a gastric GI stromal tumor using the helix-snaring technique
(2023) QUADROS, L. G. de; BRUNALDI, V. O.; SILVA, M. C.; GALVAO NETO, M.; GALA, K.; DAYYEH, B. Abu
conferenceObject
SYSTEMATIC REVIEW AND META-ANALYSIS OF COLON CAPSULE ENDOSCOPY ACCURACY FOR COLORECTAL CANCER SCREENING. AN ALTERNATIVE DURING THE COVID ERA?
(2021) SULBARAN, Marianny; BERNARDO, Wanderley M.; BUSTAMANTE-LOPEZ, Leonardo A.; SAKAI, Christiano M.; SAKAI, Paulo; NAHAS, Sergio C.; MOURA, Eduardo G. De
article 0 Citação(ões) na Scopus
Endoscopic retrograde cholangiopancreatography (ERCP) approach for patients with Roux-en-Y gastric bypass: a comparative study between four ERCP techniques with proposed management algorithm
(2024) GHAZI, Rabih; RAZZAK, Farah Abdul; KERBAGE, Anthony; BRUNALDI, Vitor; STORM, Andrew C.; VARGAS, Eric J.; BOFILL-GARCIA, Aliana; CHANDRASEKHARA, Vinay; LAW, Ryan J.; MARTIN, John A.; GHANEM, Omar M.; PETERSEN, Bret T.; DAYYEH, Barham K. Abu
Background: Endoscopic retrograde cholangiopancreatography (ERCP) is technically challenging in patients with Roux-en-Y gastric bypass (RYGB) due to altered anatomy.Objective: To compare the procedural and clinical outcomes of 4 different ERCP techniques in RYGB patients.Setting: Academic tertiary referral center in the United States. Methods: A retrospective cohort study including patients with RYGB anatomy who underwent an ERCP between January 2015 and September 2020. We compared procedural success and adverse events (AEs) rates of balloon-assisted enteroscopy (BAE), gastrostomy-assisted ERCP (GAE), endoscopic ultrasound (EUS)-directed transgastric ERCP (EDGE), and rendezvous guidewire-assisted ERCP (RGA).Results: Seventy-eight RYGB patients underwent a total of 132 ERCPs. The mean age was 60 +/- 11.8 years, with female predominance (85.7%). The ERCP procedures performed were BAE (n = 64; 48.5%), GAE (n = 18; 13.7%), EDGE (n = 25; 18.9%), and RGA (n = 25; 18.9%), with overall procedure success rates of 64.1%, 100%, 89.5%, and 91.7%, respectively. All approaches were superior to BAE (GAE versus BAE, P =.003; EDGE versus BAE, P =.034; RGA versus BAE, P =.011). The overall AE rates were 10.9%, 11.1%, 15.8 %, and 25.0%, respectively. There was no statistical difference in AEs. There were also no differences in bleeding, post-ERCP pancreatitis, and perforation rates between the 4 approaches.Conclusion: Procedure success was similar between GAE, RGA, and EDGE, but superior to BAE. AE rates were similar between approaches. (Surg Obes Relat Dis 2024;20:53-61.) (c) 2024 American Society for Metabolic and Bariatric Surgery.
article
Complex Intrahepatic Lithiasis: A Case Report of Combined Treatment With Surgical Exploration of the Bilioenteric Anastomosis and Laser Lithotripsy by Cholangioscopy
(2023) SANTOS, Marcos Eduardo Lera dos; SASSO, Joao Guilherme Ribeiro Jordao; FIGUEIRA, Estela R.; OLIVEIRA, Victor L. De; ARABI, Arthur Youssif Mota; MEIRA JUNIOR, Jose Donizeti; SILVA, Nathalia Camin Calixto Sarroche da; MOURA, Diogo Turiani De; JUKEMURA, Jose; MOURA, Eduardo Guimaraes De
Intrahepatic lithiasis, or hepatolithiasis, is an endemic disease in southeast Asia, although, with immigration from Eastern countries, the incidence of this pathology is rising worldwide. The Latin American experience demonstrates morbidity and mortality compatible with other Western countries, but minimally invasive procedures are lacking. We demonstrate a case of a combined surgical and endoscopic approach for stone clearance.We present a case of a 47-year-old female patient with biliary enteric anastomosis to treat recurrent pyogenic cholangitis resulting from intrahepatic lithiasis. The patient was admitted to the emergency room, presented with a new episode of cholangitis, and submitted to transcutaneous hepatobiliary drainage. The multidisciplinary approach, including the endoscopic and surgical teams, successfully performed the stone clearance with laser lithotripsy and stone removal by open access. The postoperative period was uneventful, and the patient did not present any sign of recurrence after one year. A combined surgical and endoscopic approach achieved short-term clinical and technical success in this novel case. Moreover, individualizing cases requiring open surgical access is feasible, which allows a combined endoscopic approach with safety.
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