LIM/41 - Laboratório de Investigação Médica do Sistema Músculo-esquelético

O Laboratório de Investigação Médica do Sistema Musculo-esquelético é ligado ao Departamento de Ortopedia e Traumatologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: alterações degenerativas e estruturais do aparelho locomotor; análise das performances de fixadores externos e osteossínteses na estabilização do sistema musculoesquelético; análise funcional do movimento; biomecânica do aparelho locomotor; desenvolvimento para ensaios e modelos de substituições articulares; ensaios sobre instabilidades articulares; regeneração e reparação musculoesquelética.

Site oficial:


Recent Submissions

  1. Joint position statement of the International Federation of Sports Medicine (FIMS) and European Federation of Sports Medicine Associations (EFSMA) on the IOC framework on fairness, inclusion and non-discrimination based on gender identity and sex variations

    BMJ OPEN SPORT & EXERCISE MEDICINE, v.8, n.1, article ID e001273, 6p, 2022

    The IOC recently published its framework on fairness, inclusion and non-discrimination based on gender identity and sex variations. This framework is drafted mainly from a human rights perspective, with less consideration for medical/scientific issues. The framework places the onus for gender eli...

  2. Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors A Randomized Clinical Trial

    JAMA ONCOLOGY, v.8, n.3, p.345-353, 2022

    IMPORTANCE The use of perioperative, prophylactic, intravenous antibiotics is standard practice to reduce the risk of surgical site infection after oncologic resection and complex endoprosthetic reconstruction for lower extremity bone tumors. However, evidence guiding the duration of prophylactic...

  3. Protecting olympic participants from COVID-19: the trialled and tested process

    BRITISH JOURNAL OF SPORTS MEDICINE, v.55, n.23, p.1321-1323, 2021


    ACTA ORTOPEDICA BRASILEIRA, v.30, n.1, article ID e253503, 4p, 2022

    Introduction: To evaluate the relationship between the genetic polymorphism of matrix metalloproteinases 1 and 13 and post-traumatic elbow stiffness, as well as the association of other risk factors with this condition. Materials and methods: We evaluated 20 patients with posttraumatic elbow stif...

  5. Delays in hospital admissions in patients with fractures across 18 low-income and middle-income countries (INORMUS): a prospective observational study

    LANCET GLOBAL HEALTH, v.8, n.5, p.E711-E720, 2020

    Background The Lancet Commission on Global Surgery established the Three Delays framework, categorising delays in accessing timely surgical care into delays in seeking care (First Delay), reaching care (Second Delay), and receiving care (Third Delay). Globally, knowledge gaps regarding delays for...

  6. A cross-cultural mixed methods validation study of the spinal cord injury quality of life basic dataset (SCI QoL-BDS)

    SPINAL CORD, v.60, n.2, p.177-186, 2022

    Study design Mixed methods inquiry using cognitive interviews and thematic content analysis. Objectives Cross-validation of the concept of quality of life (QoL) and of the International Spinal Cord Injury Quality of Life Basic DataSet (SCI QoL-BDS) items across five sites in four countries: Unite...

  7. Commentary: Effects of Whole Body Electrostimulation Associated With Body Weight Training on Functional Capacity and Body Composition in Inactive Older People

    FRONTIERS IN PHYSIOLOGY, v.12, article ID 735818, 4p, 2021


    ACTA ORTOPEDICA BRASILEIRA, v.30, n.1, article ID e248404, 4p, 2022

    Introduction: The radiographic and surgical findings, and treatment of radiocarpal fracture dislocations, were analyzed retrospectively in 40 patients. Materials and Methods: All patients were classified according to Dumontier's radiological classification and compared with the surgical findings....

  9. Use of small animal PET-CT imaging for in vivo assessment of tendon-to-bone healing: A pilot study

    JOURNAL OF ORTHOPAEDIC SURGERY, v.30, n.1, article ID 23094990221076654, 9p, 2022

    Background The availability of non-invasive means to evaluate and monitor tendon-bone healing processes in-vivo is limited. Micro Positron-Emission-Tomography (mu PET) using F-18-Fluoride is a minimally invasive imaging modality, with which osteoblast activity and bone turnover can be assessed. T...

  10. Tissue Engineering and Cell Therapy for Cartilage Repair: Preclinical Evaluation Methods

    TISSUE ENGINEERING PART C-METHODS, v.28, n.2, p.73-82, 2022

    A chondral injury is a limiting disease that can affect the quality of life and be an economic burden due to the cost of immediate treatment and loss in work productivity. If left untreated, such an injury may progress to osteoarthritis, a degenerative and debilitating joint disease characterized...