Laboratórios de Investigação Médica - LIMs

Os Laboratórios de Investigação Médica (LIMs) foram criados em decorrência da Reforma Universitária de 1969 (Lei de Diretrizes e Bases da Educação Nacional), implantada em 1970, através da qual os laboratórios de pesquisa passaram a ocupar área física da Faculdade e a receber materiais e recursos humanos do Hospital das Clínicas. Pelo Decreto 9720 de 20 de abril de 1977, o Hospital das Clínicas FMUSP incorporou os Laboratórios de Investigação Médica.

Os LIMs abrigam mais de 200 grupos de pesquisa, que são acadêmica e cientificamente vinculados aos Departamentos da FMUSP e administrativamente vinculados ao HC-FMUSP; possuindo as seguintes finalidades: desenvolver pesquisa científica; padronizar novas técnicas e métodos de diagnóstico possibilitando sua implantação para atendimento de pacientes em outras unidades do HC; promover a formação de pesquisadores em pesquisa básica e aplicada; servir de campo de ensino e treinamento de estudantes de escolas de nível superior cujos currículos sejam relacionados com as ciências da saúde; servir de campo de desenvolvimento e treinamento para profissionais da saúde e realizar cursos no campo da medicina e da saúde.

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Recent Submissions

  1. COVID-19 and Influenza coinfection: The rise of Omicron and H3N2 in Brazil-2022

    TRAVEL MEDICINE AND INFECTIOUS DISEASE, v.46, article ID 102262, 2p, 2022

  2. Measurement of Pubofemoral Distance in the Diagnosis of Developmental Dysplasia of the Hip Sensitivity and Specificity

    JOURNAL OF ULTRASOUND IN MEDICINE, v.41, n.5, p.1205-1212, 2022

    Objectives To evaluate the accuracy of measurement of the pubofemoral distance (PFD) for the diagnosis of developmental dysplasia of the hip (DDH), using the Graf method as the reference standard. Methods This was a prospective diagnostic accuracy study evaluating 1980 hips in at-risk neonates. T...

  3. The War Is on: The Immune System against Glioblastoma-How Can NK Cells Drive This Battle?

    BIOMEDICINES, v.10, n.2, article ID 400, 41p, 2022

    Natural killer (NK) cells are innate lymphocytes that play an important role in immuno-surveillance, acting alongside other immune cells in the response against various types of malignant tumors and the prevention of metastasis. Since their discovery in the 1970s, they have been thoroughly studie...

  4. Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study

    MOLECULAR PSYCHIATRY, v.27, n.2, p.1167-1176, 2022

    Neuroanatomical abnormalities have been reported along a continuum from at-risk stages, including high schizotypy, to early and chronic psychosis. However, a comprehensive neuroanatomical mapping of schizotypy remains to be established. The authors conducted the first large-scale meta-analyses of...

  5. Aerobic exercise in severe mental illness: requirements from the perspective of sports medicine


    Major depression, bipolar disorder, and schizophrenia are severe mental illnesses. Despite receiving psychopharmacological and psychosocial treatments, about half of patients develop a chronic course with residual cognitive and negative symptoms and have a high risk for cardiovascular disease and...

  6. Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health

    FRONTIERS IN PSYCHIATRY, v.13, article ID 815718, 16p, 2022

    The Federal Ministry of Education and Research (BMBF) issued a call for a new nationwide research network on mental disorders, the German Center of Mental Health (DZPG). The Munich/Augsburg consortium was selected to participate as one of six partner sites with its concept ""Precision in Mental H...

  7. <p>(???????)Associations of dynamic driving pressure and mechanical power with postoperative pulmonary complications-posthoc analysis of two randomised clinical trials in open abdominal surgery</p>

    ECLINICALMEDICINE, v.47, article ID 101397, 11p, 2022

    Background While an association of the intraoperative driving pressure with postoperative pulmonary complications has been described before, it is uncertain whether the intraoperative mechanical power is associated with postoperative pulmonary complications.& nbsp;Methods Posthoc analysis of two ...

  8. Comparison of weather station and climate reanalysis data for modelling temperature-related mortality

    SCIENTIFIC REPORTS, v.12, n.1, article ID 5178, 14p, 2022

    Epidemiological analyses of health risks associated with non-optimal temperature are traditionally based on ground observations from weather stations that offer limited spatial and temporal coverage. Climate reanalysis represents an alternative option that provide complete spatio-temporal exposur...

  9. Fluctuating temperature modifies heat-mortality association around the globe

    INNOVATION, v.3, n.2, article ID 100225, 8p, 2022

    Studies have investigated the effects of heat and temperature variability (TV) on mortality. However, few assessed whether TV modifies the heat-mortality association. Data on daily temperature and mortality in the warm season were collected from 717 locations across 36 countries. TV was calculate...

  10. Aspectos fundamentais da farmacoterapia no idoso

    Faustino, Christine Grützmann; Passarelli, Maria Cristina Guerra. Aspectos fundamentais da farmacoterapia no idoso. In: Jacob Filho, Wilson; Serrano, Priscila; Onodera, Eduardo (eds); Auler Junior, José Otávio Costa; Yu, Luis (coords). Geriatria. RIO DE JANEIRO: Atheneu, 2019. p.327-338. (Manual do médico-residente do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo)