Laboratórios de Investigação Médica - LIMs

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Os Laboratórios de Investigação Médica (LIMs) foram criados em decorrência da Reforma Universitária de 1969 (Lei de Diretrizes e Bases da Educação Nacional), implantada em 1970, através da qual os laboratórios de pesquisa passaram a ocupar área física da Faculdade e a receber materiais e recursos humanos do Hospital das Clínicas. Pelo Decreto 9720 de 20 de abril de 1977, o Hospital das Clínicas FMUSP incorporou os Laboratórios de Investigação Médica.

Os LIMs abrigam mais de 200 grupos de pesquisa, que são acadêmica e cientificamente vinculados aos Departamentos da FMUSP e administrativamente vinculados ao HC-FMUSP; possuindo as seguintes finalidades: desenvolver pesquisa científica; padronizar novas técnicas e métodos de diagnóstico possibilitando sua implantação para atendimento de pacientes em outras unidades do HC; promover a formação de pesquisadores em pesquisa básica e aplicada; servir de campo de ensino e treinamento de estudantes de escolas de nível superior cujos currículos sejam relacionados com as ciências da saúde; servir de campo de desenvolvimento e treinamento para profissionais da saúde e realizar cursos no campo da medicina e da saúde.

Site oficial: http://lims.fm.usp.br/

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Recent Submissions

  1. Antibody- Based Immunotherapy Combined With Antimycotic Drug TMP- SMX to Treat Infection With Paracoccidioides brasiliensis

    FRONTIERS IN IMMUNOLOGY, v.12, article ID 725882, 12p, 2021

    Monoclonal antibodies (mAbs) are promising alternatives to treat infectious diseases, especially given their potential for applications in combination therapies with antimicrobial drugs to enhance the antifungal efficacy. Protection mediated by mAbs used to treat experimental paracoccidioidomycos...

  2. Ongoing host-shift speciation in Plasmodium simium

    TRENDS IN PARASITOLOGY, v.37, n.11, p.940-942, 2021

    Plasmodium simium, a malaria parasite that infects platyrrhine monkeys and humans in the New World, is nearly identical to Plasmodium vivax. Recent genomic comparative analyses of these sister species have identified elevated divergence in a gene that may underlie P. simium adaptation to non-huma...

  3. Food insecurity, food waste, food behaviours and cooking confidence of UK citizens at the start of the COVID-19 lockdown

    BRITISH FOOD JOURNAL, v.123, n.9, Special Issue, p.2959-2978, 2021

    Purpose The current pilot study explored food insecurity, food waste, food related behaviours and cooking confidence of UK consumers following the COVID-19 lockdown. Design/methodology/approach Data were collected from 473 UK-based consumers (63% female) in March 2020. A cross-sectional online su...

  4. School meals consumption is associated with a better diet quality of Brazilian adolescents: results from the PeNSE 2015 survey

    PUBLIC HEALTH NUTRITION, v.24, n.18, p.6512-6520, 2021

    Objective: To assess the association between the consumption of school meals offered by the National School Feeding Program (PNAE, in the Portuguese acronym) and the diet quality of adolescents aged 11 to 19 years from Brazilian public schools. Design: Cross-sectional. Setting: Public schools in ...

  5. Polygenic risk scores across the extended psychosis spectrum

    TRANSLATIONAL PSYCHIATRY, v.11, n.1, article ID 600, 11p, 2021

    As early detection of symptoms in the subclinical to clinical psychosis spectrum may improve health outcomes, knowing the probabilistic susceptibility of developing a disorder could guide mitigation measures and clinical intervention. In this context, polygenic risk scores (PRSs) quantifying the ...

  6. New strategies for targeting kinase networks in cancer

    JOURNAL OF BIOLOGICAL CHEMISTRY, v.297, n.4, article ID 101128, 14p, 2021

    Targeted strategies against specific driver molecules of cancer have brought about many advances in cancer treatment since the early success of the first small-molecule inhibitor Gleevec. Today, there are a multitude of targeted therapies approved by the Food and Drug Administration for the treat...

  7. Daily Leucine Intake Is Positively Associated with Lower Limb Skeletal Muscle Mass and Strength in the Elderly

    NUTRIENTS, v.13, n.10, article ID 3536, 7p, 2021

    Higher daily protein intake, with an emphasis on leucine content, is thought to mitigate age-related anabolic resistance, potentially counteracting age-related morphological and functional declines. The present study investigated potential associations between total daily leucine intake and depen...

  8. Traffic-related air pollution and endurance exercise: Characterizing non-targeted serum metabolomics profiling

    ENVIRONMENTAL POLLUTION, v.291, article ID 118204, 7p, 2021

    Although the exposure to traffic-related air pollution (TRAP) has emerged as one of main problem worldwide to inhabitants' health in urban centers, its impact on metabolic responses during exercise is poorly understood. The aim of study was to characterize the profile of non-target serum metabolo...

  9. Fonoaudiologia ao longo da vida

    Pantano, Telma; Stivanin, Luciene; Belan, Ariella Fornachari Ribeiro. Fonoaudiologia ao longo da vida. In: Miguel, Euripedes Constantino; Lafer, Beny; Elkis, Helio; Forlenza, Orestes Vicente; Carvalho, Ana Lopes; Brunoni, Andre Russowsky; Teng, Chei Tung; Humes, Eduardo de Castro; Corchs, Felipe; Demetrio, Frederico Navas; Polanczyk, Guilherme Vanoni; Almeida, Karla Mathias de; Valliengo, Leandro da Costa Lane; Vieira, Marcio Eduardo Bergamini; Scanavino, Marco de Tubino; Kayo, Monica; Soares, Odeilton Tadeu; Fráguas Júnior, Renério; Scivoletto, Sandra (eds); Guimarães-Fernandes, Flávio (coord). Clínica psiquiátrica: a terapêutica psiquiátrica [2. ed., ampl. e atual], v.v.3. BARUERI: Manole, 2021. p.496-511.

  10. Terapia comportamental dealética

    Dornelles, Vinícius Guimarães; Branãs, Marcelo José Abduch Adas; Croci, Marcos Signoretti; Martinho Jr, Eduardo. Terapia comportamental dealética. In: Miguel, Euripedes Constantino; Lafer, Beny; Elkis, Helio; Forlenza, Orestes Vicente; Carvalho, Ana Lopes; Brunoni, Andre Russowsky; Teng, Chei Tung; Humes, Eduardo de Castro; Corchs, Felipe; Demetrio, Frederico Navas; Polanczyk, Guilherme Vanoni; Almeida, Karla Mathias de; Valliengo, Leandro da Costa Lane; Vieira, Marcio Eduardo Bergamini; Scanavino, Marco de Tubino; Kayo, Monica; Soares, Odeilton Tadeu; Fráguas Júnior, Renério; Scivoletto, Sandra (eds); Guimarães-Fernandes, Flávio (coord). Clínica psiquiátrica: a terapêutica psiquiátrica [2. ed., ampl. e atual], v.v.3. BARUERI: Manole, 2021. p.279-287.