Laboratórios de Investigação Médica - LIMs

Laboratórios de Investigação Médica - LIMs

 


Foto: Fabíola R. Sanches
Os Laboratórios de Investigação Médica (LIMs) foram criados em decorrência da Reforma Universitária de 1969 (Lei de Diretrizes e Bases da Educação Nacional), implantada em 1970, através da qual os laboratórios de pesquisa passaram a ocupar área física da Faculdade e a receber materiais e recursos humanos do Hospital das Clínicas. Pelo Decreto 9720 de 20 de abril de 1977, o Hospital das Clínicas FMUSP incorporou os Laboratórios de Investigação Médica.

Os LIMs abrigam mais de 200 grupos de pesquisa, que são acadêmica e cientificamente vinculados aos Departamentos da FMUSP e administrativamente vinculados ao HC-FMUSP; possuindo as seguintes finalidades: desenvolver pesquisa científica; padronizar novas técnicas e métodos de diagnóstico possibilitando sua implantação para atendimento de pacientes em outras unidades do HC; promover a formação de pesquisadores em pesquisa básica e aplicada; servir de campo de ensino e treinamento de estudantes de escolas de nível superior cujos currículos sejam relacionados com as ciências da saúde; servir de campo de desenvolvimento e treinamento para profissionais da saúde e realizar cursos no campo da medicina e da saúde.

Site oficial: http://www.lims.fm.usp.br/

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Recent Submissions

  • SISTI, G.; PACCOSI, S.; PARENTI, A.; SERAVALLI, V; LINARI, C.; TOMMASO, M. Di; WITKIN, S. (COMENIUS UNIV, BRATISLAVA I, SLOVAKIA, 2020)
    AIM: We hypothesized that elevated vaginal levels of matrix metalloproteinase-8 (MMP-8), interleukin-8 (IL-8) and the 70kDa heat shock protein (hsp70), compounds involved in inflammatory responses, correlated with a short ...
  • BARBIERI, Ana Amelia; COSTA, Andre Luiz Ferreira; GOMES, Joao Pedro Perez; RICARDO, Ana Lucia Franco; BRAZ-SILVA, Paulo Henrique; LOPES, Sergio Lucio Pereira de Castro (TAYLOR & FRANCIS LTD, ABINGDON, ENGLAND, 2020)
    Objectives: To compare the volume and voxel intensity of articular disc and lateral pterygoid muscle (LPM) between a group of migraine patients and a control group (those without history of headache) by using magnetic ...
  • SARMENTO, Dmitry Jose de Santana; ANTUNES, Rosana Saint Clair Correia Aires; CRISTELLI, Marina; BRAZ-SILVA, Paulo Henrique; MACIEL, Rafael; PESTANA, Jose Osmar Medina de Abreu; GALLOTTINI, Marina (TAYLOR & FRANCIS LTD, ABINGDON, ENGLAND, 2020)
    Objective: To identify the oral lesions of individuals with kidney disease immediately before and shortly after kidney transplantation, taking into account the immunosuppressive regimen, antiviral prophylaxis and type of ...
  • KIM, Yeon Jung; SAIKI, Carlos Eduardo Takeshi; SILVA, Karoline; MASSUDA, Carlos Kiyoshi Moreira; FALONI, Ana Paula de Souza; BRAZ-SILVA, Paulo Henrique; PALLOS, Debora; SENDYK, Wilson Roberto (HINDAWI LTD, LONDON, ENGLAND, 2020)
    Background. The aim of this study was to assess the volumetric stability and bone formation in grafts with Bio-Oss and autogenous bone at different proportions in rabbit calvaria. Material and Methods. Ten rabbits received ...
  • SELVA, Andreia La; NEGREIROS, Renata Matalon; BEZERRA, Daniela Teixeira; ROSA, Ellen Perin; PAVESI, Vanessa Christina Santos; NAVARRO, Ricardo Scarparo; BELLO-SILVA, Marina Stella; RAMALHO, Karen Muller; ARANHA, Ana Cecilia Correa; BRAZ-SILVA, Paulo Henrique; FERNANDES, Kristianne Porta Santos; BUSSADORI, Sandra Kalil; HORLIANA, Anna Carolina Ratto Tempestini (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)
    Background: Lesions of herpes labialis are caused by the herpes simplex virus type 1 and cause pain and aesthetic compromise. It is characterized by the formation of small vesicles that coalesce and rupture forming extremely ...
  • SANTOS, Wellington Pereira dos; GOMES, Joao Pedro Perez; NUSSI, Amanda Drumstas; ALTEMANI, Joao Mauricio; SANTOS, Maria Teresa Botti Rodrigues dos; HASSEUS, Bengt; GIGLIO, Daniel; BRAZ-SILVA, Paulo Henrique; COSTA, Andre Luiz Ferreira (HINDAWI LTD, LONDON, ENGLAND, 2020)
    The multimodal approach for patients with head and neck cancer (HNC) includes treatment with chemoradiation therapy (CRT). A common concern regarding CRT side effects is the occurrence of structural and physiological ...
  • FECCHIO, Alan; CHAGAS, Carolina R. F.; BELL, Jeffrey A.; KIRCHGATTER, Karin (ELSEVIER, AMSTERDAM, NETHERLANDS, 2020)
    Haemosporidian parasites of the genera Plasmodium, Leucocytozoon, and Haemoproteus are one of the most prevalent and widely studied groups of parasites infecting birds. Plasmodium is the most well-known haemosporidian as ...
  • MARIANO, Luciano Inacio; CARAMELLI, Paulo; GUIMARAES, Henrique Cerqueira; GAMBOGI, Leandro Boson; MOURA, Millena Vieira Brandao; YASSUDA, Onica Sanches; TEIXEIRA, Antonto Lucio; SOUZA, Leonardo Cruz de (IOS PRESS, AMSTERDAM, NETHERLANDS, 2020)
    Background: Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD) share cognitive and behavioral symptoms, such as apathy. Social cognition measurements are useful in distinguishing bvFTD from AD, ...
  • MAIA, Emanuella Gomes; PASSOS, Camila Mendes dos; LEVY, Renata Bertazzi; MARTINS, Ana Paula Bortoletto; MAIS, Lais Amaral; CLARO, Rafael Moreira (CAMBRIDGE UNIV PRESS, CAMBRIDGE, ENGLAND, 2020)
    Objective: To measure change in price of food groups over time (1995-2030) in Brazil, considering the Brazilian Dietary Guidelines' recommendations. Design: Data from the Household Budget Survey (2008-2009 HBS) and the ...
  • AZEREDO, Catarina Machado; LEITE, Maria Alvim; RAUBER, Fernanda; RICARDO, Camila Zancheta; LEVY, Renata Bertazzi (REVISTA DE SAUDE PUBLICA, SAO PAULO, BRAZIL, 2020)
    OBJECTIVE: To describe students protected by laws and exposed to soft drinks sales and assess whether forbidding laws are associated with lower availability of these beverages. METHODS: We identified laws forbidding ...
  • CANHADA, Scheine Leite; LUFT, Vivian Cristine; GIATTI, Luana; DUNCAN, Bruce Bartholow; CHOR, Dora; FONSECA, Maria de Jesus M. da; MATOS, Sheila Maria Alvim; MOLINA, Maria del Carmen Bisi; BARRETO, Sandhi Maria; LEVY, Renata Bertazzi; SCHMIDT, Maria Ines (CAMBRIDGE UNIV PRESS, CAMBRIDGE, ENGLAND, 2020)
    Objective: To evaluate the association of ultra-processed food (UPF) consumption with gains in weight and waist circumference, and incident overweight/obesity, in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) ...
  • PASSOS, Camila Mendes dos; MAIA, Emanuella Gomes; LEVY, Renata Bertazzi; MARTINS, Ana Paula Bortoletto; CLARO, Rafael Moreira (ELSEVIER SCI LTD, OXFORD, ENGLAND, 2020)
    Background and aims: To estimate the relationship between the price of ultra-processed foods and prevalence of obesity in Brazil and examine whether the relationship differed according to socioeconomic status. Methods and ...
  • ANDRADE, Giovanna Calixto; GOMBI-VACA, Maria Fernanda; LOUZADA, Maria Laura da Costa; AZEREDO, Catarina Machado; LEVY, Renata Bertazzi (CAMBRIDGE UNIV PRESS, CAMBRIDGE, ENGLAND, 2020)
    Objective: To describe out-of-home consumption according to the purpose and extent of industrial processing and also evaluate the association between eating out and ultra-processed food consumption, taking account of ...
  • MUELLER, Mario; AJDACIC-GROSS, Vladeta; VETRELLA, Antonio Besi; PREISIG, Martin; CASTELAO, Enrique; LASSERRE, Aurelie; RODGERS, Stephanie; ROESSLER, Wulf; VETTER, Stefan; SEIFRITZ, Erich; VANDELEUR, Caroline (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2020)
    Alcohol use disorders (AUD) are often comorbid with other disorders with high levels of impairment, which is of relevance for the development and the progression of the disease. Evidence shows that AUD varies greatly with ...
  • BOLTON, Thomas A. W.; WOTRUBA, Diana; BUECHLER, Roman; THEODORIDOU, Anastasia; MICHELS, Lars; KOLLIAS, Spyros; ROESSLER, Wulf; HEEKEREN, Karsten; VILLE, Dimitri Van de (FRONTIERS MEDIA SA, LAUSANNE, SWITZERLAND, 2020)
    Emerging evidence has attributed altered network coordination between the default mode, central executive, and salience networks (DMN/CEN/SAL) to disturbances seen in schizophrenia, but little is known for at-risk psychosis ...
  • RAUCHMANN, Boris-Stephan; GHASEMINEJAD, Farhad; KEESER, Daniel; KELLER-VARADY, Katriona; SCHNEIDER-AXMANN, Thomas; TAKAHASHI, Shun; KARALI, Temmuz; HELMS, Gunther; DECHENT, Peter; MAURUS, Isabel; HASAN, Alkomiet; WOBROCK, Thomas; ERTL-WAGNER, Birgit; SCHMITT, Andrea; MALCHOW, Berend; FALKAI, Peter (SPRINGER, NEW YORK, UNITED STATES, 2020)
    Higher glutamate and glutamine (together: Glx) and lower N-acetyl-aspartate (NAA) levels were reported in schizophrenia. Endurance training normalizes NAA in the hippocampus, but its effects on other metabolites in the ...
  • ROESSLER, Julian; ROESSLER, Wulf; SEIFRITZ, Erich; UNTERRASSNER, Lui; WYSS, Thomas; HAKER, Helene; WOTRUBA, Diana (OXFORD UNIV PRESS, OXFORD, ENGLAND, 2020)
    Dopamine is involved in the pathophysiology of schizophrenia. Disrupted salience processing by the salience network (SN) may be a central link between dysregulated dopamine function and psychotic symptoms. However, ...
  • FALKAI, Peter; RAABE, Florian; BOGERTS, Bernhard; SCHNEIDER-AXMANN, Thomas; MALCHOW, Berend; TATSCH, Laura; HUBER, Verena; SLAPAKOVA, Lenka; DOBROWOLNY, Henrik; SCHMITZ, Christoph; CANTUTI-CASTELVETRI, Ludovico; SIMONS, Mikael; STEINER, Johann; SCHMITT, Andrea (SPRINGER HEIDELBERG, HEIDELBERG, GERMANY, 2020)
    In schizophrenia, decreased hippocampal volume, reduced oligodendrocyte numbers in hippocampal cornu ammonis (CA) subregions and reduced neuron number in the dentate gyrus have been reported; reduced oligodendrocyte numbers ...
  • COUTO, Rodrigo de Macedo; RANZANI, Otavio T.; WALDMAN, Eliseu Alves (OXFORD UNIV PRESS INC, CARY, USA, 2019)
    Zoonotic tuberculosis is a reemerging infectious disease in high-income countries and a neglected one in low- and middle-income countries. Despite major advances in its control as a result of milk pasteurization, its global ...
  • MAZZINARI, Guido; DIAZ-CAMBRONERO, Oscar; ALONSO-INIGO, Jose Miguel; GARCIA-GREGORIO, Nuria; AYAS-MONTERO, Begona; IBANEZ, Jose Luis; NETO, Ary Serpa; BALL, Lorenzo; ABREU, Marcelo Gama de; PELOSI, Paolo; MAUPOEY, Javier; NAVARRO, Maria Pilar Argente; SCHULTZ, Marcus J. (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)
    Background: Pneumoperitoneum for laparoscopic surgery is associated with a rise of driving pressure. The authors aimed to assess the effects of positive end-expiratory pressure (PEEP) on driving pressure at varying ...

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