LIM/55 - Laboratório de Urologia

O Laboratório de Urologia é ligado ao Departamento de Cirurgia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: determinação de fatores prognósticos no câncer urogenital; estabelecimento de linhagens tumorais para estudos in vitro de novos fármacos para o tratamento do carcinoma urogenital; desenvolvimento de modelos animais de tumores urogenitais para estudos in vivo; desenvolvimento de fármacos para o tratamento da disfunção erétil; disfunção miccional; integração de novos tecidos, técnicas e materiais biológicos na reconstrução do trato urinário.

Site oficial: http://limhc.fm.usp.br/portal/lim55-laboratorio-de-urologia/

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Recent Submissions

  1. Use of artificial intelligence for sepsis risk prediction after flexible ureteroscopy: a systematic review

    REVISTA DO COLéGIO BRASILEIRO DE CIRURGIõES, v.50, p.e20233561, 2023

    ABSTRACT Introduction: flexible ureteroscopy is a minimally invasive surgical technique used for the treatment of renal lithiasis. Postoperative urosepsis is a rare but potentially fatal complication. Traditional models used to predict the risk of this condition have limited accuracy, while model...

  2. Transcriptomic analysis reveals a tissue-specific loss of identity during ageing and cancer

    BMC GENOMICS, v.24, n.1, article ID 644, 13p, 2023

    IntroductionUnderstanding changes in cell identity in cancer and ageing is of great importance. In this work, we analyzed how gene expression changes in human tissues are associated with tissue specificity during cancer and ageing using transcriptome data from TCGA and GTEx.ResultsWe found signif...

  3. The Effect of Gene Editing by CRISPR-Cas9 of miR-21 and the Indirect Target MMP9 in Metastatic Prostate Cancer

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.24, n.19, article ID 14847, 15p, 2023

    Prostate cancer (PCa) has a high prevalence and represents an important health problem, with an increased risk of metastasis. With the advance of CRISPR-Cas9 genome editing, new possibilities have been created for investigating PCa. The technique is effective in knockout oncogenes, reducing tumor...

  4. Lymphadenectomy in Prostate Cancer: Technique and Outcomes

    Lestingi, J. F. P.; Salas, R. S.; Yoshioka, K.; Coelho, R. F.. Lymphadenectomy in Prostate Cancer: Technique and Outcomes. In: . Robotic Urologic Surgery: Third Edition: SPRINGER INTERNATIONAL PUBLISHING, 2022. p.305-349.

    Despite recent advances in imaging, pelvic lymph node dissection (PLND) remains the gold standard modality for nodal staging in prostate cancer (PCa) patients. There remains significant debate about PLND: the odds of finding positive pelvic lymph nodes are proportional to the extent of the PLND; ...

  5. CARDIORENAL DYSFUNCTION IN MICE SUBMITTED TO AORTIC STENOSIS AND TREATED WITH SODIUM OXALATE

    JOURNAL OF HYPERTENSION, v.41, suppl.3, p.E227-E227, 2023

  6. PEYRONIE'S DISEASE SURGERY GRAFTING AREA REDUCTION: A COMPARATIVE ASSESSMENT BETWEEN IGRAFTER APP VS DOUBLE Y USING VALIDATED LOW-COST 3D-PRINTED PENILE MODELS

    JOURNAL OF SEXUAL MEDICINE, v.20, suppl.4, p.62-62, 2023

  7. 3D PENILE RECONSTRUCTION IMAGING IN COMPLEX PEYRONIE'S DISEASE (PD): PROOF OF CONCEPT STUDY

    JOURNAL OF SEXUAL MEDICINE, v.20, suppl.1, article ID qdad060.162, 2p, 2023

  8. CHRONOLOGY OF ENDOGENOUS TESTOSTERONE RECOVERY FOLLOWING ANDROGEN DEPRIVATION THERAPY CESSATION - RESULTS FROM A PROSPECTIVE ANALYSIS

    JOURNAL OF SEXUAL MEDICINE, v.20, suppl.1, article ID qdad060.057, 2p, 2023

  9. CORRELATION BETWEEN LIBIDO AND TESTOSTERONE: ESTRADIOL RATIO IN MEN WITH SEXUAL DYSFUNCTION

    JOURNAL OF SEXUAL MEDICINE, v.20, suppl.1, article ID qdad060.052, 1p, 2023

  10. Impact of COVID-19 on surgical procedures for stress urinary incontinence in the Brazilian public health system

    INTERNATIONAL UROGYNECOLOGY JOURNAL, v.34, n.8, p.1949-1954, 2023

    Introduction and hypothesisThe objective was to characterize the impact of the COVID-19 pandemic on the surgical treatment of female stress urinary incontinence (FSUI) in Brazil.MethodsThis study was conducted with population-based data from the Brazilian public health system database. We obtaine...