LIM/43 - Laboratório de Medicina Nuclear

O Laboratório de Medicina Nuclear é ligado ao Departamento de Radiologia e Oncologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: análise crítica dos métodos de neuroimagem funcional na avaliação das desordens neurológicas e psiquiátricas; medicina nuclear e aplicação clínica dos radioisótopos.

Site oficial: http://limhc.fm.usp.br/portal/lim43-laboratorio-de-medicina-nuclear/

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Recent Submissions

  1. Validation of automated image co-registration integrated into in-house software for voxel-based internal dosimetry on single-photon emission computed tomography images

    RADIOLOGIA BRASILEIRA, v.56, n.3, p.137-144, 2023

    Abstract Objective: To develop an automated co-registration system and test its performance, with and without a fiducial marker, on single-photon emission computed tomography (SPECT) images. Materials and Methods: Three SPECT/CT scans were acquired for each rotation of a Jaszczak phantom (to 0°, ...

  2. Membrane-derived particles shed by PSMA-positive cells function as pro-angiogenic stimuli in tumors

    JOURNAL OF CONTROLLED RELEASE, v.364, p.312-325, 2023

    Cell membrane-derived particles (Mp) are rounded membrane-enclosed particles that are shed from tumor cells. Mp are formed from tumor membranes and are capable of tumor targeting and immunotherapeutic agents because they share membrane homology with parental cells; thus, they are under considerat...

  3. Letter to the Editor: The theoretical challenges of routinely using [<SUP>18</SUP>F]FDG PET/MRI combined with chest HRCT for early cancer detection in asymptomatic patients

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, v.50, n.13, p.3824-3825, 2023

  4. Cortical thickness is related to working memory performance after non-invasive brain stimulation

    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, v.56, article ID e12945, 8p, 2023

    Non-invasive brain stimulation (NIBS) probing the dorsolateral prefrontal cortex (DLPFC) has been shown to have little effect on working memory. The variability of NIBS responses might be explained by inter-subject brain anatomical variability. We investigated whether baseline cortical brain thic...

  5. Patentometric analysis as a subsid to the management of technological innovation: a case study in radiopharmaceuticals for cancer

    ENCONTROS BIBLI-REVISTA ELETRONICA DE BIBLIOTECONOMIA E CIENCIA DA INFORMACAO, v.28, 2023

    Objective: Prospect the evolution of patent applications onIdentify, extract, process data, organize and make available technological information in the form of graphical interfaces described in oncology patents containing the radioisotopes gallium-68 (68Ga), copper-64 (64Cu) and zirconium-89...

  6. Repeatability of brown adipose tissue activation measured by [<SUP>18</SUP>F]FDG PET after beta3-adrenergic stimuli in a mouse model

    NUCLEAR MEDICINE AND BIOLOGY, v.126, article ID 108390, 5p, 2023

    This study aimed to evaluate the repeatability of brown adipose tissue (BAT) activation measured by [F-18]FDG-PET after beta3-adrenergic stimuli with CL316243 in mice.Methods: Male C57BL/6 mice underwent [F-18]FDG-PET at baseline without stimulation (T0-NS), on three consecutive days after intrav...

  7. Nuclear Medicine in Endocrine Disorders: Diagnosis and Therapy

    Coura-Filho, G. B.; de Campos, A. L. M.; de Oliveira, M. T. S. (eds). Nuclear Medicine in Endocrine Disorders: Diagnosis and TherapySPRINGER INTERNATIONAL PUBLISHING, 2022. 336p.

    This book presents up-to-date information on the general principles of diagnostic and therapeutic nuclear medicine in the context of endocrinology. The content is divided into six parts. Section I examines general aspects of radiopharmaceuticals, scintigraphy, single-photon emission computed tomo...

  8. Exercise and Parkinson’s disease: Linking in the cannabinoid type 1 (CB1) and type 2 (CB2) and mu-opioid receptors

    Chacur, M.; Binda, K. H.; Real, C. C.. Exercise and Parkinson’s disease: Linking in the cannabinoid type 1 (CB1) and type 2 (CB2) and mu-opioid receptors. In: . Neurobiology and Physiology of the Endocannabinoid System: ELSEVIER, 2023. p.137-147.

    Parkinson’s disease (PD) has motor alterations as typical symptoms; however, there are also a high prevalence of nonmotor symptoms such as pain, balance, depression with high impact on patient quality life. Pain is present in around of 85% of PD patients and is associated with abnormal processing...

  9. PET-CT of ovarian cancer

    Buchpiguel, C. A.. PET-CT of ovarian cancer. In: . Clinical PET-CT in Radiology: Integrated Imaging in Oncology: SPRINGER NEW YORK, 2011. p.331-338.

    PET-CT has no current role in the initial diagnosis of ovarian cancer. While imaging studies are not the basis of staging, imaging studies are often performed preoperatively (usually CT or MRI of the abdomen and pelvis) on patients suspected of advanced disease. A major advantage of PET-CT is the...

  10. Development and external validation of a multivariable [<SUP>68</SUP>Ga]Ga-PSMA-11 PET-based prediction model for lymph node involvement in men with intermediate or high-risk prostate cancer

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, v.50, n.10, p.3137-3146, 2023

    PurposeTo develop and evaluate a lymph node invasion (LNI) prediction model for men staged with [Ga-68]Ga-PSMA-11 PET.MethodsA consecutive sample of intermediate to high-risk prostate cancer (PCa) patients undergoing [Ga-68]Ga-PSMA-11 PET, extended pelvic lymph node dissection (ePLND), and radica...