Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/3909
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
dc.contributor.author | GARCIA, C. B. | |
dc.contributor.author | PERANDINI, L. A. | |
dc.contributor.author | SEGURO, L. P. C. | |
dc.contributor.author | GUALANO, B. | |
dc.contributor.author | ROSCHEL, H. | |
dc.contributor.author | BONFA, E. | |
dc.contributor.author | BORBA, E. F. | |
dc.contributor.author | SA-PINTO, A. L. | |
dc.date.accessioned | 2014-01-28T22:17:19Z | |
dc.date.available | 2014-01-28T22:17:19Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | LUPUS, v.22, n.9, p.928-931, 2013 | |
dc.identifier.issn | 0961-2033 | |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/3909 | |
dc.description.abstract | Primary antiphospholipid syndrome (PAPS) is associated with increased risk of cardiovascular disease and mortality. Aerobic capacity and cardiac autonomic control are also associated with these risks. The aim of our study was to assess aerobic capacity and cardiac autonomic control in PAPS patients. Thirteen women with PAPS and 13 healthy controls matched for age, gender, and body mass index were enrolled for the study. Both groups were sedentary and were not under chronotropic, antidepressants and hypolipemiant drugs. All subjects performed a treadmill-graded maximal exercise. Aerobic capacity was assessed by peak oxygen uptake (VO(2)peak), time at anaerobic ventilatory threshold (VAT) and respiratory compensation point (RCP) and time-to-exhaustion, whereas cardiac autonomic control was assessed by chronotropic reserve (CR) and heart rate recovery at the first and second minutes after graded exercise (HRR1min and HRR2min, respectively). All aerobic capacity indexes were reduced more in PAPS patients than in healthy subjects: VO(2)peak (30.2 +/- 4.7 vs 34.6 +/- 4.3ml.kg(-1).min(-1), p=0.021), time at VAT (3.0 +/- 1.5 vs 5.0 +/- 2.0min, p=0.016), time at RCP (6.5 +/- 2.0 vs 8.0 +/- 2.0min, p=0.050), time-to-exhaustion (8.5 +/- 2.0 vs 11.0 +/- 2.5min, p=0.010). HRR1min (22 +/- 9 vs 30 +/- 7 bpm, p=0.032) and HRR2min (33 +/- 9 vs 46 +/- 8bpm, p=0.002) were delayed in PAPS patients compared to healthy controls but CR was not significantly different (p=0.272). In conclusion, an impaired aerobic capacity and cardiac autonomic control was identified in PAPS. | |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) [306963/2011-6, 301411/2009-3] | |
dc.description.sponsorship | Federico Foundation | |
dc.description.sponsorship | Coordenacao de Aperfeicoamento de Pessoal de Ensino Superior (CAPES) | |
dc.language.iso | eng | |
dc.publisher | SAGE PUBLICATIONS LTD | |
dc.relation.ispartof | Lupus | |
dc.rights | restrictedAccess | |
dc.subject | Exercise | |
dc.subject | autonomic nervous systemic | |
dc.subject | antiphospholipid syndrome | |
dc.subject | oxygen uptake | |
dc.subject.other | heart-rate recovery | |
dc.subject.other | systemic-lupus-erythematosus | |
dc.subject.other | rate-variability | |
dc.subject.other | chronotropic incompetence | |
dc.subject.other | ankylosing-spondylitis | |
dc.subject.other | gas-exchange | |
dc.subject.other | risk-factors | |
dc.subject.other | mortality | |
dc.subject.other | fibromyalgia | |
dc.subject.other | therapy | |
dc.title | Impaired aerobic exercise capacity and cardiac autonomic control in primary antiphospholipid syndrome | |
dc.type | article | |
dc.rights.holder | Copyright SAGE PUBLICATIONS LTD | |
dc.identifier.doi | 10.1177/0961203313497415 | |
dc.identifier.pmid | 23894046 | |
dc.identifier.pmid | 23894046 | |
dc.subject.wos | Rheumatology | |
dc.type.category | original article | |
dc.type.version | publishedVersion | |
hcfmusp.author.external | ROSCHEL, H.:Univ Sao Paulo, Sch Med, Div Rheumatol, BR-01246903 Sao Paulo, Brazil; Univ Sao Paulo, Sch Phys Educ & Sport, BR-01246903 Sao Paulo, Brazil | |
hcfmusp.description.beginpage | 928 | |
hcfmusp.description.endpage | 931 | |
hcfmusp.description.issue | 9 | |
hcfmusp.description.volume | 22 | |
hcfmusp.origem | WOS | |
hcfmusp.origem.id | WOS:000322320700008 | |
hcfmusp.origem.id | 2-s2.0-84880859004 | |
hcfmusp.publisher.city | LONDON | |
hcfmusp.publisher.country | ENGLAND | |
hcfmusp.relation.reference | Arena R, 2010, SCAND J MED SCI SPOR, V20, P291, DOI 10.1111/j.1600-0838.2009.00883.x | |
hcfmusp.relation.reference | Bilora Franca, 2012, Int J Gen Med, V5, P339, DOI 10.2147/IJGM.S29822 | |
hcfmusp.relation.reference | Blair SN, 1996, JAMA-J AM MED ASSOC, V276, P205, DOI 10.1001/jama.276.3.205 | |
hcfmusp.relation.reference | Bostrom C, 2008, LUPUS, V17, P100, DOI 10.1177/0961203307085670 | |
hcfmusp.relation.reference | Brubaker PH, 2011, CIRCULATION, V123, P1010, DOI 10.1161/CIRCULATIONAHA.110.940577 | |
hcfmusp.relation.reference | Carter R, 1999, RESP MED, V93, P700, DOI 10.1016/S0954-6111(99)90036-7 | |
hcfmusp.relation.reference | Cimen B, 2001, Clin Rheumatol, V20, P168 | |
hcfmusp.relation.reference | Cole CR, 1999, NEW ENGL J MED, V341, P1351, DOI 10.1056/NEJM199910283411804 | |
hcfmusp.relation.reference | da Cunha Ribeiro Roberta Potenza, 2011, Arthritis Res Ther, V13, pR190, DOI 10.1186/ar3519 | |
hcfmusp.relation.reference | do Prado DML, 2011, LUPUS, V20, P717, DOI 10.1177/0961203310397081 | |
hcfmusp.relation.reference | Espinosa G, 2010, NAT REV RHEUMATOL, V6, P296, DOI 10.1038/nrrheum.2010.47 | |
hcfmusp.relation.reference | Flachenecker P, 2012, AUTOIMMUN REV, V11, P219, DOI 10.1016/j.autrev.2011.05.016 | |
hcfmusp.relation.reference | Forte S, 1999, J RHEUMATOL, V26, P2591 | |
hcfmusp.relation.reference | Franklin BA, 2012, CURR SPORT MED REP, V11, P201, DOI 10.1249/JSR.0b013e31825dabd4 | |
hcfmusp.relation.reference | Hassett AL, 2009, RHEUM DIS CLIN N AM, V35, P393, DOI 10.1016/j.rdc.2009.05.003 | |
hcfmusp.relation.reference | Hassett AL, 2007, APPL PSYCHOPHYS BIOF, V32, P1, DOI 10.1007/s10484-006-9028-0 | |
hcfmusp.relation.reference | Janse van Rensburg DC, 2012, INT J RHEUM DIS, V15, P419 | |
hcfmusp.relation.reference | Kaya EB, 2010, CLIN RES CARDIOL, V99, P803, DOI 10.1007/s00392-010-0187-x | |
hcfmusp.relation.reference | Miossi R, 2012, ARTHRIT CARE RES, V64, P1159, DOI 10.1002/acr.21678 | |
hcfmusp.relation.reference | Miyakis S, 2006, J THROMB HAEMOST, V4, P295, DOI 10.1111/j.1538-7836.2006.01753.x | |
hcfmusp.relation.reference | Oliveira NC, 2009, INT J SPORTS MED, V30, P728, DOI 10.1055/s-0029-1224180 | |
hcfmusp.relation.reference | Perandini LA, 2012, AUTOIMMUN REV, V12, P218, DOI 10.1016/j.autrev.2012.06.007 | |
hcfmusp.relation.reference | Ruiz-Irastorza G, 2010, LANCET, V376, P1498, DOI 10.1016/S0140-6736(10)60709-X | |
hcfmusp.relation.reference | SANDVIK L, 1995, CORONARY ARTERY DIS, V6, P667, DOI 10.1097/00019501-199508000-00012 | |
hcfmusp.relation.reference | Shibata Y, 1998, THROMB HAEMOSTASIS, V80, P203 | |
hcfmusp.relation.reference | Tsuji H, 1996, CIRCULATION, V94, P2850 | |
hcfmusp.relation.reference | WASSERMA.K, 1973, J APPL PHYSIOL, V35, P236 | |
dc.description.index | MEDLINE | |
hcfmusp.remissive.sponsorship | CAPES | |
hcfmusp.remissive.sponsorship | CNPq | |
hcfmusp.remissive.sponsorship | Federico Foundation | |
hcfmusp.remissive.sponsorship | CAPES | |
hcfmusp.remissive.sponsorship | CNPq | |
hcfmusp.remissive.sponsorship | Federico Foundation | |
hcfmusp.citation.scopus | 6 | |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCM Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/17 Artigos e Materiais de Revistas Científicas - ODS/03 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_GARCIA_Impaired_aerobic_exercise_capacity_and_cardiac_autonomic_control_2013.PDF Restricted Access | publishedVersion (English) | 114.58 kB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.