NAFLD: Challenges and opportunities to address the public health problem in Latin America
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Citações na Scopus
17
Tipo de produção
article
Data de publicação
2021
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER ESPANA
Autores
PABLO, Arab Juan
ANTONIO, Diaz Luis
MELISA, Dirchwolf
MARK, Henry E.
LAZARUS, Jeffrey V.
VAUGHAN, Elly
MENDEZ-SANCHEZ, Nahum
GADANO, Adrian
ARRESE, Marco
Citação
ANNALS OF HEPATOLOGY, v.24, article ID 100359, 5p, 2021
Resumo
Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions worldwide. Collectively, Latin American countries have some of the highest obesity rates in the world and the fastest-growing prevalence of type 2 diabetes mellitus (T2DM). Since obesity and T2DM are intrinsically linked with NAFLD, epidemiological projections are worrisome. In addition to this adverse epidemiological setting, the region of Latin America faces unique challenges and obstacles to addressing the growing burden of NAFLD. In this article, on the occasion of the International NASH Day on June 10, 2021, we describe the main challenges and opportunities to improve care of people living with NAFLD in Latin America. Among the major challenges to be tackled are: lack of disease awareness, limited educational opportunities for healthcare personnel and general public, health system fragmentation, and lack of effective strategies for the prevention and effective treatment of NAFLD and common comorbidities, namely obesity and T2DM. Wide dissemination of current concepts on NAFLD, and extensive collaboration between scientific societies, governments, non-governmental organizations, pharmaceutical industry, and other stakeholders is urgently needed to advance the NAFLD public health policies agenda that allows us to address this disease with a whole of society approach. (c) 2021 Published by Elsevier Espa?a, S.L.U. on behalf of Fundaci?n Cl?nica M?dica Sur, A.C. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/
Palavras-chave
Non-alcoholic steatohepatitis, NASH, Non-alcoholic fatty liver disease, NAFLD, MAFLD, Public policies
Referências
- Alexander M, 2018, BMC MED, V16, DOI 10.1186/s12916-018-1103-x
- Ampuero J, 2020, CLIN GASTROENTEROL H, V18, P216, DOI 10.1016/j.cgh.2019.05.051
- [Anonymous], 2003, HEPATOLOGY, V37, P244
- Bergqvist CJ, 2013, INTERN MED J, V43, P247, DOI 10.1111/j.1445-5994.2012.02848.x
- Blais P, 2015, AM J GASTROENTEROL, V110, P10, DOI 10.1038/ajg.2014.134
- Boursier J, 2021, JHEP REP, V3, DOI 10.1016/j.jhepr.2020.100219
- Boutari C, 2021, METABOLISM, V122, DOI 10.1016/j.metabol.2021.154781
- Bril F, 2017, DIABETES CARE, V40, P419, DOI 10.2337/dc16-1787
- Castera L, 2019, GASTROENTEROLOGY, V156, P1264, DOI 10.1053/j.gastro.2018.12.036
- Chalasani N, 2018, HEPATOLOGY, V67, P328, DOI 10.1002/hep.29367
- Eslam M, 2020, J HEPATOL, V73, P202, DOI 10.1016/j.jhep.2020.03.039
- Eslam M, 2020, GASTROENTEROLOGY, V158, P1999, DOI 10.1053/j.gastro.2019.11.312
- Fouad Y, 2021, J HEPATOL, V74, P1254, DOI 10.1016/j.jhep.2020.12.035
- Gallardo-Rincon H, 2021, PRIM CARE DIABETES, V15, P352, DOI 10.1016/j.pcd.2020.10.001
- Hardy T, 2020, CONTEMP CLIN TRIALS, V98, DOI 10.1016/j.cct.2020.106175
- Lazarus JV, 2020, J HEPATOL, V72, P14, DOI 10.1016/j.jhep.2019.08.027
- Lonardo A, 2021, ADV THER, V38, P2130, DOI 10.1007/s12325-021-01690-1
- Marciano S, 2021, Rev Gastroenterol Mex (Engl Ed), DOI 10.1016/j.rgmx.2020.08.006
- McPherson S, 2017, AM J GASTROENTEROL, V112, P740, DOI 10.1038/ajg.2016.453
- Mendez-Sanchez N, 2021, J HEPATOL, V75, P221, DOI 10.1016/j.jhep.2021.04.021
- Mendez-Sanchez N, 2021, LANCET GASTROENTEROL, V6, P65, DOI [10.1016/S2468-1253(20)30340-x, 10.1016/S2468-1253(20)30340-X]
- Mendez-Sanchez N, 2018, AM J GASTROENTEROL, V113, P1274, DOI 10.1038/s41395-018-0047-2
- Mendizabal M, 2017, LIVER TRANSPLANT, V23, P1210, DOI 10.1002/lt.24793
- O'Hara J, 2020, JHEP REP, V2, DOI 10.1016/j.jhepr.2020.100142
- Ofosu A, 2018, ANN GASTROENTEROL, V31, P288, DOI 10.20524/aog.2018.0240
- Arab JP, 2020, ANN HEPATOL, V19, P674, DOI 10.1016/j.aohep.2020.09.006
- Palacios C, 2021, PUBLIC HEALTH NUTR, P1
- Patel PJ, 2018, INTERN MED J, V48, P144, DOI 10.1111/imj.13667
- Pinto Marques Souza de Oliveira Claudia, 2019, Clin Liver Dis (Hoboken), V13, P39, DOI 10.1002/cld.759
- Powell EE, 2021, LANCET, V397, P2212, DOI 10.1016/S0140-6736(20)32511-3
- Sanyal AJ, 2018, BMC MED, V16, DOI 10.1186/s12916-018-1149-9
- Sepulveda-Villegas M, 2019, PLOS ONE, V14, DOI 10.1371/journal.pone.0208926
- Singh A, 2020, DIGEST DIS SCI, V65, P978, DOI 10.1007/s10620-019-05700-9
- The Economist Intelligence Unit, 2021, NAFLD SOUND AL GLOB
- Treeprasertsuk S, 2012, LIVER INT, V32, P945, DOI 10.1111/j.1478-3231.2011.02753.x
- Younossi Z, 2019, HEPATOLOGY, V69, P2672, DOI 10.1002/hep.30251
- Younossi ZM, 2019, J HEPATOL, V70, P531, DOI 10.1016/j.jhep.2018.10.033
- Zambrano-Huailla R, 2020, ANN HEPATOL, V19, P622, DOI 10.1016/j.aohep.2020.08.066
- Zelber-Sagi S, 2017, WORLD J GASTROENTERO, V23, P1881, DOI 10.3748/wjg.v23.i10.1881