Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/44763
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | NAKANISHI, Tomoko | - |
dc.contributor.author | PIGAZZINI, Sara | - |
dc.contributor.author | DEGENHARDT, Frauke | - |
dc.contributor.author | CORDIOLI, Mattia | - |
dc.contributor.author | BUTLER-LAPORTE, Guillaume | - |
dc.contributor.author | MAYA-MILES, Douglas | - |
dc.contributor.author | BUJANDA, Luis | - |
dc.contributor.author | BOUYSRAN, Youssef | - |
dc.contributor.author | NIEMI, Mari E. K. | - |
dc.contributor.author | PALOM, Adriana | - |
dc.contributor.author | ELLINGHAUS, David | - |
dc.contributor.author | KHAN, Atlas | - |
dc.contributor.author | MARTINEZ-BUENO, Manuel | - |
dc.contributor.author | ROLKER, Selina | - |
dc.contributor.author | AMITRANO, Sara | - |
dc.contributor.author | TATO, Luisa Roade | - |
dc.contributor.author | FAVA, Francesca | - |
dc.contributor.author | SPINNER, Christoph D. | - |
dc.contributor.author | PRATI, Daniele | - |
dc.contributor.author | BERNARDO, David | - |
dc.contributor.author | GARCIA, Federico | - |
dc.contributor.author | DARCIS, Gilles | - |
dc.contributor.author | FERNANDEZ-CADENAS, Israel | - |
dc.contributor.author | HOLTER, Jan Cato | - |
dc.contributor.author | BANALES, Jesus M. | - |
dc.contributor.author | FRITHIOF, Robert | - |
dc.contributor.author | KIRYLUK, Krzysztof | - |
dc.contributor.author | DUGA, Stefano | - |
dc.contributor.author | ASSELTA, Rosanna | - |
dc.contributor.author | PEREIRA, Alexandre C. | - |
dc.contributor.author | ROMERO-GOMEZ, Manuel | - |
dc.contributor.author | NAFRIA-JIMENEZ, Beatriz | - |
dc.contributor.author | HOV, Johannes R. | - |
dc.contributor.author | MIGEOTTE, Isabelle | - |
dc.contributor.author | RENIERI, Alessandra | - |
dc.contributor.author | PLANAS, Anna M. | - |
dc.contributor.author | LUDWIG, Kerstin U. | - |
dc.contributor.author | BUTI, Maria | - |
dc.contributor.author | RAHMOUNI, Souad | - |
dc.contributor.author | ALARCON-RIQUELME, Marta E. | - |
dc.contributor.author | SCHULTE, Eva C. | - |
dc.contributor.author | FRANKE, Andre | - |
dc.contributor.author | KARLSEN, Tom H. | - |
dc.contributor.author | VALENTI, Luca | - |
dc.contributor.author | ZEBERG, Hugo | - |
dc.contributor.author | RICHARDS, J. Brent | - |
dc.contributor.author | GANNA, Andrea | - |
dc.date.accessioned | 2022-02-24T17:21:48Z | - |
dc.date.available | 2022-02-24T17:21:48Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | JOURNAL OF CLINICAL INVESTIGATION, v.131, n.23, 2021 | - |
dc.identifier.issn | 0021-9738 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/44763 | - |
dc.description.abstract | BACKGROUND. There is considerable variability in COVID-19 outcomes among younger adults, and some of this variation may be due to genetic predisposition. METHODS. We combined individual level data from 13,888 COVID-19 patients (n = 7185 hospitalized) from 17 cohorts in 9 countries to assess the association of the major common COVID-19 genetic risk factor (chromosome 3 locus tagged by rs10490770) with mortality, COVID-19-related complications, and laboratory values. We next performed metaanalyses using FinnGen and the Columbia University COVID-19 Biobank. RESULTS. We found that rs10490770 risk allele carriers experienced an increased risk of all-cause mortality (HR, 1.4; 95% CI, 1.2-1.7). Risk allele carriers had increased odds of several COVID-19 complications: severe respiratory failure (OR, 2.1; 95% CI, 1.6-2.6), venous thromboembolism (OR, 1.7; 95% CI, 1.2-2.4), and hepatic injury (OR, 1.5; 95% CI, 1.2-2.0). Risk allele carriers age 60 years and younger had higher odds of death or severe respiratory failure (OR, 2.7; 95% CI, 1.8-3.9) compared with those of more than 60 years (OR, 1.5; 95% CI, 1.2-1.8; interaction, P = 0.038). Among individuals 60 years and younger who died or experienced severe respiratory failure, 32.3% were risk-variant carriers compared with 13.9% of those not experiencing these outcomes. This risk variant improved the prediction of death or severe respiratory failure similarly to, or better than, most established clinical risk factors. CONCLUSIONS. The major common COVID-19 genetic risk factor is associated with increased risks of morbidity and mortality, which are more pronounced among individuals 60 years or younger. The effect was similar in magnitude and more common than most established clinical risk factors, suggesting potential implications for future clinical risk management. | eng |
dc.description.sponsorship | Amyndas Pharmaceuticals | - |
dc.language.iso | eng | - |
dc.publisher | AMER SOC CLINICAL INVESTIGATION INC | eng |
dc.relation.ispartof | Journal of Clinical Investigation | - |
dc.rights | restrictedAccess | eng |
dc.subject.other | vaccine | eng |
dc.title | Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality | eng |
dc.type | article | eng |
dc.rights.holder | Copyright AMER SOC CLINICAL INVESTIGATION INC | eng |
dc.contributor.groupauthor | FinnGen | - |
dc.contributor.groupauthor | COVID-19 Host Genetics Initiative | - |
dc.identifier.doi | 10.1172/JCI152386 | - |
dc.identifier.pmid | 34597274 | - |
dc.subject.wos | Medicine, Research & Experimental | eng |
dc.type.category | original article | eng |
dc.type.version | publishedVersion | eng |
hcfmusp.author.external | NAKANISHI, Tomoko:Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland; McGill Univ, Dept Human Genet, Montreal, PQ, Canada; McGill Univ, Jewish Gen Hosp, Lady Davis Inst, Montreal, PQ, Canada; Kyoto Univ, Grad Sch Med, Kyoto McGill Int Collaborat Sch Genom Med, Kyoto, Japan; Japan Soc Promot Sci, Tokyo, Japan | - |
hcfmusp.author.external | PIGAZZINI, Sara:Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland; Univ Milano Bicocca, Milan, Italy | - |
hcfmusp.author.external | DEGENHARDT, Frauke:Univ Kiel, Inst Clin Mol Biol, Kiel, Germany | - |
hcfmusp.author.external | CORDIOLI, Mattia:Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland | - |
hcfmusp.author.external | BUTLER-LAPORTE, Guillaume:McGill Univ, Jewish Gen Hosp, Lady Davis Inst, Montreal, PQ, Canada; McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada | - |
hcfmusp.author.external | MAYA-MILES, Douglas:Univ Seville, Virgen del Rocio Univ Hosp, Inst Biomed Seville, Digest Dis Unit, Seville, Spain; Inst Salud Carlos Iii ISCIII, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Madrid, Spain | - |
hcfmusp.author.external | BUJANDA, Luis:Univ Basque Country UPV EHU, Biodonostia Hlth Res Inst, Dept Liver & Gastrointestinal Dis, Donostia Univ Hosp,CIBERehd,Ikerbasque, San Sebastian, Spain | - |
hcfmusp.author.external | BOUYSRAN, Youssef:Univ Libre Bruxelles ULB, Ctr Genet Humaine, Hop Erasme, Brussels, Belgium | - |
hcfmusp.author.external | NIEMI, Mari E. K.:Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland | - |
hcfmusp.author.external | PALOM, Adriana:Hosp Univ Vall dHebron, Dept Internal Med, Liver Unit, Vall dHebron Barcelona Hosp Campus, Barcelona, Spain; Univ Autonoma Barcelona, Dept Med Bellatera, Barcelona, Spain; Vall dHebron Inst Recerca VHIR, Liver Dis, Barcelona, Spain | - |
hcfmusp.author.external | ELLINGHAUS, David:Univ Kiel, Inst Clin Mol Biol, Kiel, Germany; Univ Copenhagen, Novo Nordisk Fdn Ctr Prot Res, Fac Hlth & Med Sci, Dis Syst Biol, Copenhagen, Denmark | - |
hcfmusp.author.external | KHAN, Atlas:Columbia Univ, Vagelos Coll Phys & Surg, Dept Med, Div Nephrol, New York, NY USA | - |
hcfmusp.author.external | MARTINEZ-BUENO, Manuel:Univ Granada, GENYO, Ctr Genom & Oncol Res Pfizer, Andalusian Reg Govt, Granada, Spain | - |
hcfmusp.author.external | ROLKER, Selina:Univ Bonn, Med Fac, Inst Human Genet, Univ Hosp Bonn, Bonn, Germany | - |
hcfmusp.author.external | AMITRANO, Sara:Azienda Osped Univ Senese, Genet Med, Siena, Italy | - |
hcfmusp.author.external | TATO, Luisa Roade:Inst Salud Carlos Iii ISCIII, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Madrid, Spain; Hosp Univ Vall dHebron, Dept Internal Med, Liver Unit, Vall dHebron Barcelona Hosp Campus, Barcelona, Spain; Univ Autonoma Barcelona, Dept Med Bellatera, Barcelona, Spain | - |
hcfmusp.author.external | FAVA, Francesca:Azienda Osped Univ Senese, Genet Med, Siena, Italy; Univ Siena, Med Genet, Siena, Italy; Univ Siena, Med Biotech Hub, Dept Med Biotechnol, Siena, Italy; Univ Siena, Competence Ctr, Dept Med Biotechnol, Siena, Italy | - |
hcfmusp.author.external | SPINNER, Christoph D.:Tech Univ Munich, Univ Hosp Rechts Isar, Sch Med, Dept Internal Med 2, Munich, Germany | - |
hcfmusp.author.external | PRATI, Daniele:Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Transfus Med & Hematol, Milan, Italy | - |
hcfmusp.author.external | BERNARDO, David:Inst Salud Carlos Iii ISCIII, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Madrid, Spain; Univ Valladolid, Inst Biomed & Mol Genet IBGM, Mucosal Immunol Lab, CSIC, Valladolid, Spain | - |
hcfmusp.author.external | GARCIA, Federico:Hosp Univ Clin San Cecilio, Granada, Spain; Inst Invest Ibs Granada, Granada, Spain | - |
hcfmusp.author.external | DARCIS, Gilles:Univ Liege, GIGA Insitute, Liege, Belgium; Liege Univ Hosp CHU Liege, Liege, Belgium | - |
hcfmusp.author.external | FERNANDEZ-CADENAS, Israel:Biomed Res Inst St Pau IIB St Pau, Stroke Pharmacogen & Genet Grp, Barcelona, Spain | - |
hcfmusp.author.external | HOLTER, Jan Cato:Oslo Univ Hosp, Dept Microbiol, Oslo, Norway; Univ Oslo, Inst Clin Med, Oslo, Norway | - |
hcfmusp.author.external | BANALES, Jesus M.:Univ Basque Country UPV EHU, Biodonostia Hlth Res Inst, Dept Liver & Gastrointestinal Dis, Donostia Univ Hosp,CIBERehd,Ikerbasque, San Sebastian, Spain; Univ Navarra, Sch Sci, Dept Biochem & Genet, Pamplona, Spain | - |
hcfmusp.author.external | FRITHIOF, Robert:Uppsala Univ, Dept Surg Sci Anaesthesiol & Intens Care Med, Uppsala, Sweden | - |
hcfmusp.author.external | KIRYLUK, Krzysztof:Columbia Univ, Vagelos Coll Phys & Surg, Dept Med, Div Nephrol, New York, NY USA | - |
hcfmusp.author.external | DUGA, Stefano:Humanitas Univ, Dept Biomed Sci, Milan, Italy; IRCCS Humanitas Res Hosp, Milan, Italy | - |
hcfmusp.author.external | ASSELTA, Rosanna:Humanitas Univ, Dept Biomed Sci, Milan, Italy; IRCCS Humanitas Res Hosp, Milan, Italy | - |
hcfmusp.author.external | ROMERO-GOMEZ, Manuel:Univ Seville, Virgen del Rocio Univ Hosp, Inst Biomed Seville, Digest Dis Unit, Seville, Spain; Inst Salud Carlos Iii ISCIII, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Madrid, Spain | - |
hcfmusp.author.external | NAFRIA-JIMENEZ, Beatriz:Osakidetza Basque Hlth Serv, Donostialdea Integrated Hlth Org, Clin Biochem Dept, Sebastian, Spain | - |
hcfmusp.author.external | HOV, Johannes R.:Oslo Univ Hosp, Dept Microbiol, Oslo, Norway; Oslo Univ Hosp, Norwegian PSC Res Ctr, Oslo, Norway; Oslo Univ Hosp, Sect Gastroenterol, Dept Transplantat Med, Oslo, Norway; Oslo Univ Hosp, Res Inst Internal Med, Oslo, Norway | - |
hcfmusp.author.external | MIGEOTTE, Isabelle:Univ Libre Bruxelles ULB, Ctr Genet Humaine, Hop Erasme, Brussels, Belgium; Fonds Rech Sci FNRS, Brussels, Belgium | - |
hcfmusp.author.external | RENIERI, Alessandra:Azienda Osped Univ Senese, Genet Med, Siena, Italy; Univ Siena, Med Genet, Siena, Italy; Univ Siena, Med Biotech Hub, Dept Med Biotechnol, Siena, Italy; Univ Siena, Competence Ctr, Dept Med Biotechnol, Siena, Italy | - |
hcfmusp.author.external | PLANAS, Anna M.:Natl Spanish Res Council CSIC, Inst Biomed Researhc Barcelona IIBB, Barcelona, Spain; Inst Invest Biomed August Pi & Sunyer IDIBAPS, Barcelona, Spain | - |
hcfmusp.author.external | LUDWIG, Kerstin U.:Univ Bonn, Med Fac, Inst Human Genet, Univ Hosp Bonn, Bonn, Germany | - |
hcfmusp.author.external | BUTI, Maria:Inst Salud Carlos Iii ISCIII, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Madrid, Spain; Hosp Univ Vall dHebron, Dept Internal Med, Liver Unit, Vall dHebron Barcelona Hosp Campus, Barcelona, Spain; Univ Autonoma Barcelona, Dept Med Bellatera, Barcelona, Spain | - |
hcfmusp.author.external | RAHMOUNI, Souad:Inst Invest Ibs Granada, Granada, Spain | - |
hcfmusp.author.external | ALARCON-RIQUELME, Marta E.:Univ Granada, GENYO, Ctr Genom & Oncol Res Pfizer, Andalusian Reg Govt, Granada, Spain; Karolinska Inst, Inst Environm Med, Solna, Sweden | - |
hcfmusp.author.external | SCHULTE, Eva C.:Tech Univ Munich, Inst Virol, Helmholtz Zentrum Munchen, Munich, Germany; LMU Munich Univ, Univ Hosp, Inst Psychiat Phen & Genom, Munich, Germany; LMU Munich Univ, Univ Hosp, Dept Psychiat, Munich, Germany | - |
hcfmusp.author.external | FRANKE, Andre:Univ Kiel, Inst Clin Mol Biol, Kiel, Germany; Univ Hosp Schleswig Holstein, Campus Kiel, Kiel, Germany | - |
hcfmusp.author.external | KARLSEN, Tom H.:Univ Oslo, Inst Clin Med, Oslo, Norway; Oslo Univ Hosp, Norwegian PSC Res Ctr, Oslo, Norway; Oslo Univ Hosp, Sect Gastroenterol, Dept Transplantat Med, Oslo, Norway; Oslo Univ Hosp, Res Inst Internal Med, Oslo, Norway | - |
hcfmusp.author.external | VALENTI, Luca:Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy; Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Transfus Med & Hematol, Precis Med, Milan, Italy | - |
hcfmusp.author.external | ZEBERG, Hugo:Karolinska Inst, Dept Neurosci, Stockholm, Sweden; Max Planck Inst Evolutionary Anthropol, Leipzig, Germany | - |
hcfmusp.author.external | RICHARDS, J. Brent:McGill Univ, Dept Human Genet, Montreal, PQ, Canada; McGill Univ, Jewish Gen Hosp, Lady Davis Inst, Montreal, PQ, Canada; Univ Seville, Virgen del Rocio Univ Hosp, Inst Biomed Seville, Digest Dis Unit, Seville, Spain; Kings Coll London, Dept Twin Res, London, England | - |
hcfmusp.author.external | GANNA, Andrea:Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland; Harvard Med Sch, Massachusetts Gen Hosp, Boston, MA 02115 USA | - |
hcfmusp.description.issue | 23 | - |
hcfmusp.description.volume | 131 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | WOS:000726717300012 | - |
hcfmusp.origem.id | 2-s2.0-85118211941 | - |
hcfmusp.publisher.city | ANN ARBOR | eng |
hcfmusp.publisher.country | USA | eng |
hcfmusp.relation.reference | Altshuler DM, 2010, NATURE, V467, P52, DOI 10.1038/nature09298 | eng |
hcfmusp.relation.reference | Baric RS, 2020, NEW ENGL J MED, V383, P2684, DOI 10.1056/NEJMcibr2032888 | eng |
hcfmusp.relation.reference | Bubar KM, 2021, SCIENCE, V371, P916, DOI 10.1126/science.abe6959 | eng |
hcfmusp.relation.reference | Buitrago-Garcia D, 2020, PLOS MED, V17, DOI 10.1371/journal.pmed.1003346 | eng |
hcfmusp.relation.reference | Chaudhry R, 2020, ECLINICALMEDICINE, V25, DOI 10.1016/j.eclinm.2020.100464 | eng |
hcfmusp.relation.reference | Chua RL, 2020, NAT BIOTECHNOL, V38, P970, DOI 10.1038/s41587-020-0602-4 | eng |
hcfmusp.relation.reference | Del Valle DM, 2020, NAT MED, V26, P1636, DOI 10.1038/s41591-020-1051-9 | eng |
hcfmusp.relation.reference | Di Maria E, 2020, HUM GENOMICS, V14, DOI 10.1186/s40246-020-00280-6 | eng |
hcfmusp.relation.reference | Dooling K, 2021, MMWR-MORBID MORTAL W, V69, P1657, DOI 10.15585/mmwr.mm695152e2 | eng |
hcfmusp.relation.reference | Downes DJ., NAT GENET, V53, P1606 | eng |
hcfmusp.relation.reference | Ellinghaus D, 2020, NEW ENGL J MED, V383, P1522, DOI 10.1056/NEJMoa2020283 | eng |
hcfmusp.relation.reference | Feng YCA, FINDINGS INSIGHTS GE, DOI [10.1101/2020.11.20.20234302, DOI 10.1101/2020.11.20.20234302] | eng |
hcfmusp.relation.reference | Fry A, 2017, AM J EPIDEMIOL, V186, P1026, DOI 10.1093/aje/kwx246 | eng |
hcfmusp.relation.reference | Griffith GJ, 2020, NAT COMMUN, V11, DOI 10.1038/s41467-020-19478-2 | eng |
hcfmusp.relation.reference | Karczewski KJ, 2020, NATURE, V581, P434, DOI 10.1038/s41586-020-2308-7 | eng |
hcfmusp.relation.reference | Khalil BA, 2021, COMPUT STRUCT BIOTEC, V19, P976, DOI 10.1016/j.csbj.2021.01.034 | eng |
hcfmusp.relation.reference | Kosmicki JA, 2021, AM J HUM GENET, V108, P1350, DOI [10.1016/j.ajhg.2021.017, 10.1016/j.ajhg.2021.05.017] | eng |
hcfmusp.relation.reference | Liao MF, 2020, NAT MED, V26, P842, DOI 10.1038/s41591-020-0901-9 | eng |
hcfmusp.relation.reference | Marshall JC, 2020, LANCET INFECT DIS, V20, pE192, DOI 10.1016/S1473-3099(20)30483-7 | eng |
hcfmusp.relation.reference | Mckee M, 2020, NAT MED, V26, P640, DOI 10.1038/s41591-020-0863-y | eng |
hcfmusp.relation.reference | Merrill JT, 2020, NAT REV RHEUMATOL, V16, P581, DOI 10.1038/s41584-020-0474-5 | eng |
hcfmusp.relation.reference | Moradi EV, 2021, AM J EMERG MED, V40, P11, DOI 10.1016/j.ajem.2020.12.003 | eng |
hcfmusp.relation.reference | Nordestgaard BG, 2013, EUR HEART J, V34, P3478, DOI 10.1093/eurheartj/eht273 | eng |
hcfmusp.relation.reference | Novelli G, 2021, HUM GENOMICS, V15, DOI 10.1186/s40246-021-00326-3 | eng |
hcfmusp.relation.reference | O'Driscoll M, 2020, NATURE, DOI 10.1038/s41586-020-2918-0 | eng |
hcfmusp.relation.reference | Olarte L, 2006, ARCH NEUROL-CHICAGO, V63, P1586, DOI 10.1001/archneur.63.11.1586 | eng |
hcfmusp.relation.reference | Pairo-Castineira E, 2021, NATURE, V591, P92, DOI 10.1038/s41586-020-03065-y | eng |
hcfmusp.relation.reference | Payne D.J., 2021, CXCR6 CXCL16 AXIS LI, DOI [10.1101/2021.01.25.428125, DOI 10.1101/2021.01.25.428125] | eng |
hcfmusp.relation.reference | Polack FP, 2020, NEW ENGL J MED, V383, P2603, DOI 10.1056/NEJMoa2034577 | eng |
hcfmusp.relation.reference | Pourcher V, 2020, QEIOS, DOI [10.32388/WPP19W.3, DOI 10.32388/WPP19W.3] | eng |
hcfmusp.relation.reference | Poustchi Hossein, 2021, Lancet Infect Dis, V21, P473, DOI 10.1016/S1473-3099(20)30858-6 | eng |
hcfmusp.relation.reference | Purcell S, 2007, AM J HUM GENET, V81, P559, DOI 10.1086/519795 | eng |
hcfmusp.relation.reference | Rosales-Salyano Vh, LIVER RES, V5, P21 | eng |
hcfmusp.relation.reference | Signorelli C, 2020, INT J PUBLIC HEALTH, V65, P1435, DOI 10.1007/s00038-020-01486-0 | eng |
hcfmusp.relation.reference | Smieszek SP, ROLE FYVE COILED COI, DOI [10.1101/2021.01.22.21250070, DOI 10.1101/2021.01.22.21250070] | eng |
hcfmusp.relation.reference | Su SL, 2012, J ORTHOP RES, V30, P9, DOI 10.1002/jor.21494 | eng |
hcfmusp.relation.reference | Tagging ANIM, 2021, NATURE, V600, P472, DOI 10.1038/s41586-021-03767-x | eng |
hcfmusp.relation.reference | van der Kolk DM, 2010, BREAST CANCER RES TR, V124, P643, DOI 10.1007/s10549-010-0805-3 | eng |
hcfmusp.relation.reference | Vuille-Dit-Bille RN, 2015, AMINO ACIDS, V47, P693, DOI 10.1007/s00726-014-1889-6 | eng |
hcfmusp.relation.reference | Williamson EJ, 2020, NATURE, V584, P430, DOI 10.1038/s41586-020-2521-4 | eng |
hcfmusp.relation.reference | Yan L, 2020, NAT MACH INTELL, V2, P283, DOI 10.1038/s42256-020-0180-7 | eng |
hcfmusp.relation.reference | Yao Y, 2021, SIGNAL TRANSDUCT TAR, V6, DOI 10.1038/s41392-021-00519-1 | eng |
hcfmusp.relation.reference | Zeberg H, 2020, NATURE, V587, P610, DOI 10.1038/s41586-020-2818-3 | eng |
dc.description.index | MEDLINE | eng |
dc.identifier.eissn | 1558-8238 | - |
hcfmusp.citation.scopus | 57 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - COVID-19 Artigos e Materiais de Revistas Científicas - HC/InCor Artigos e Materiais de Revistas Científicas - LIM/13 Artigos e Materiais de Revistas Científicas - ODS/03 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_NAKANISHI_Agedependent_impact_of_the_major_common_genetic_risk_2021.PDF Restricted Access | publishedVersion (English) | 1.42 MB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.