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Title: | Diagnosis, treatment and maxillofacial rehabilitation in rhinocerebral mucormycosis patient: A case report and review of the literature |
Authors: | SANTOS, Rennan Luiz Oliveira Dos; ELCHIN, Cintia Baena; GUIGUER-PINTO, Vitor Ancheschi; VASCONCELOS, Dewton de Moraes; FERREIRA, Mauricio Domingues; DIAS, Reinaldo Brito; SUGAYA, Norberto Nobuo; PAULA, Claudete Rodrigues; COTO, Neide Pena |
Citation: | JOURNAL DE MYCOLOGIE MEDICALE, v.32, n.1, article ID 101211, 7p, 2022 |
Abstract: | Mucormycosis is an aggressive, rare and opportunistic infectious disease, with a high mortality rate. Etiologic agents are filamentous fungi, and infection among humans normally occurs through spore inhalation. A 61-year-old male individual, presenting left eye amaurosis, dark epistaxis, hyperalgesia and malodor underwent clinical examination, which detected ulcerative lesion and wide bone exposure in the hard palate and alveo-lar ridge. Direct microbiological examination, microbiological culture and lesion biopsy were performed. Non-septate smooth fungal hyphae forming right angles with each other were observed through the direct microbiological examination. Microbiological culture revealed fast-growing fungal colonies with cottony tex-ture, identified as Rhizopus sp. Histopathological examination exhibited necrosis areas, intense mononuclear inflammatory infiltrate and bulky hyphae, thus concluding the mucormycosis diagnosis. Amphotericin B antifungal therapy and surgical intervention were adopted as treatment. The patient was then rehabilitated with maxillofacial prosthesis, subsequently to the healing of the surgical wound. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/31 Artigos e Materiais de Revistas Científicas - LIM/56 |
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