Effect of Light Emitted by Diode as Treatment of Radiodermatitis

Nenhuma Miniatura disponível
Citações na Scopus
0
Tipo de produção
conferenceObject
Data de publicação
2022
DOI
Scopus
Web of Science
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER
Autores
SANTOS, Pedro Henrique Gianjoppe dos
GONCALES, Lara Andressa Ordonhe
REGO, Carolina Lopo
SILVA, B. M.
TEIXEIRA, M. H. A. S.
FEITOSA, Y. O.
Citação
XXVII BRAZILIAN CONGRESS ON BIOMEDICAL ENGINEERING, CBEB 2020, p.1231-1236, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Radiotherapy can cause radiodermatitis in 85-90% in oncologic patients. There are several therapeutic alternatives to treat radiodermatitis with variable results. A new option is the use of light emitted-diode (LED) to treat this condition. We analyzed twenty male Wistar rats weighing 200-250 g. All the animals underwent a radiotherapy session. After 15 days, the animals were divided into four groups: control (no treatment) and LED 630 nm, 850 nm, 630 + 850 nm. The LED treatment was applied every two days until the 21 days). We analyzed the macroscopic aspect of radiodermatitis before and after treatment. After this phase, samples were collected for histological (HE). Macro and microscopic analysis indicated positive effects with exposure to light, especially with the association between wavelengths 630 and 850 nm, resulting in a reduction in the severity of radiodermatitis to grade 2-2.5. In the histological analysis, photobiomodulation increased the division and migration of cells in the basal layer of the epidermis, demonstrating the regenerative potential of this treatment in the effects of radiotherapy, increasing the speed of epithelialization of the lesion. This study suggested that the association of 630 + 850 nm improved radiodermatitis regeneration.
Palavras-chave
Radiotherapy, Photobiomodulation, Radiodermatitis
URI
https://observatorio.fm.usp.br/handle/OPI/50149
Referências
  1. Antunes HS, 2017, ORAL ONCOL, V71, P11, DOI 10.1016/j.oraloncology.2017.05.018
  2. Bray FN, 2016, DERMATOLOGY THER, V6, P185, DOI 10.1007/s13555-016-0120-y
  3. Censabella S, 2016, SUPPORT CARE CANCER, V24, P3925, DOI 10.1007/s00520-016-3232-0
  4. Chan RJ, 2014, BMC CANCER, V14, DOI 10.1186/1471-2407-14-53
  5. Corazza AV, 2005, THESIS U SAO PAULO S, DOI [10.11606/D.82.2005.tde-25072006-095614, DOI 10.11606/D.82.2005.TDE-25072006-095614]
  6. COX JD, 1995, INT J RADIAT ONCOL, V31, P1341, DOI 10.1016/0360-3016(95)00060-C
  7. de Freitas LF, 2016, IEEE J SEL TOP QUANT, V22, DOI 10.1109/JSTQE.2016.2561201
  8. DeLand MM, 2007, LASER SURG MED, V39, P164, DOI 10.1002/lsm.20455
  9. Gianfaldoni Serena, 2017, Open Access Maced J Med Sci, V5, P521, DOI 10.3889/oamjms.2017.122
  10. KARU TI, 1987, IEEE J QUANTUM ELECT, V23, P1703, DOI 10.1109/JQE.1987.1073236
  11. Park JH, 2020, LASER MED SCI, V35, P1119, DOI 10.1007/s10103-019-02930-1
  12. Robijns J, 2020, PHOTOBIOMOD PHOTOMED, V38, P332, DOI 10.1089/photob.2019.4761
  13. Robijns J, 2019, CURR OPIN ONCOL, V31, P291, DOI 10.1097/CCO.0000000000000511
  14. Robijns J, 2018, LASER SURG MED, V50, P763, DOI 10.1002/lsm.22804
  15. Simunovic Z, 2020, LASERS MED DENT BASI
  16. Strouthos I, 2017, STRAHLENTHER ONKOL, V193, P491, DOI 10.1007/s00066-017-1117-x
  17. Zhang XD, 2018, WORLD J SURG ONCOL, V16, DOI 10.1186/s12957-018-1522-3

Coleções
Comunicações em Eventos - FM/MCG
Comunicações em Eventos - HC/ICHC
Comunicações em Eventos - HC/InRad
Comunicações em Eventos - LIM/04