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https://observatorio.fm.usp.br/handle/OPI/53889
Title: | An update on viral-induced cutaneous lymphoproliferative disorders. CME Part I |
Authors: | PLAZA, Jose A.; GRU, Alejandro A.; SANGUEZA, Omar P.; LOURENCO, Silvia V.; PUCCIO, Francisco B.; SANCHES, Jose A.; MIYASHIRO, Denis; TOUSSAINT, Sonia; SANGUEZA, Martin J. |
Citation: | JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, v.88, n.5, p.965-980, 2023 |
Abstract: | Viral-induced cutaneous T-cell lymphomas are an uncommon group of lymphoproliferative disorders characterized by a viral infection of T and natural killer (NK) cells. This group of cutaneous T-cell lymphomas is more commonly encountered in Asians and Native Americans from Central and South America compared with Western populations. Viral-associated lymphoproliferative disorders include a spectrum of entities that range from nonneoplastic lesions, such as chronic active Epstein-Barr virus infection and infective dermatitis to malignant diseases, such as extranodal NK/T-cell lymphoma, hydroa vacciniforme-like T-cell lymphoma, and adult T-cell leukemia/lymphoma. This review article will focus on hydroa vacciniforme-like lymphoproliferative disorder, extranodal NK/T-cell lymphoma, adult T-cell leukemia/lymphoma, lymphomatoid granulomatosis, and Epstein-Barr virus-positive mucocutaneous ulcers. We will review the pathogenesis of these conditions and the challenges of making a timely diagnosis in early-stage disease and discuss the common clinicopathologic manifestations, mutational landscape, and approaches to treat these highly aggressive and frequently lethal types of lymphoma. ( J Am Acad Dermatol 2023;88:965-80.) |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MDT Artigos e Materiais de Revistas Científicas - HC/ICESP Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/53 Artigos e Materiais de Revistas Científicas - LIM/56 Artigos e Materiais de Revistas Científicas - ODS/03 |
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