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https://observatorio.fm.usp.br/handle/OPI/54049
Title: | Heat exposure and hospitalisation for epileptic seizures: A nationwide case-crossover study in Brazil |
Authors: | ZHANG, Yiwen; XU, Rongbin; YE, Tingting; YU, Wenhua; YU, Pei; CHEN, Zhuying; MAHENDRAN, Rahini; SALDIVA, Paulo Hilario Nascimento; COEL, Micheline de Sousa Zanotti Stagliorio; GUO, Yuming; LI, Shanshan |
Citation: | URBAN CLIMATE, v.49, article ID 101497, 11p, 2023 |
Abstract: | Climate change is increasing human exposure to heat, especially in tropical regions such as Brazil where temperature reaches up to 40 degrees C in summer. However, the association between heat exposure and epileptic seizures has not been well demonstrated in Brazil, where lifetime preva-lence of epilepsy can range from 11.9/1000 to 21/1000. We collected a total of 225,699 hospi-talisation records for epileptic seizures of 1816 municipalities in Brazil, during the hot season from 2000 to 2015, covering nearly 79% of the national population. We implemented a time -stratified case-crossover design combined with distributed lag model with further stratified in-vestigations regarding sex, age, socioeconomic status and region. We found temperature impact threshold was 26 degrees C in Brazil nationally. Every 1 degrees C increase from the threshold was associated with an overall 4.3% increased risk of hospitalisation for epileptic seizures on the current day of hospital admission and up to seven days before, which was most pronounced on the second-day exposure to heat. Females, individuals aged 20-30 and persons living in high-income or Southeast regions were more vulnerable. Our results highlight the enhanced risk of heat exposure for epi-lepsy patients and could contribute to epilepsy management, such as forecasting epileptic sei-zures. Multi-dimensional adaptive strategies were proposed, covering individual protection, occupational health surveillance, and urban planning management, aiming to reduce heat -induced hospitalisations for epilepsy, and be generalizable to other heat-related diseases. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MPT Artigos e Materiais de Revistas Científicas - HC/InCor Artigos e Materiais de Revistas Científicas - LIM/05 Artigos e Materiais de Revistas Científicas - ODS/11 Artigos e Materiais de Revistas Científicas - ODS/13 |
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art_ZHANG_Heat_exposure_and_hospitalisation_for_epileptic_seizures_A_2023.PDF Restricted Access | publishedVersion (English) | 1.52 MB | Adobe PDF | View/Open Request a copy |
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