Characterisation of the coexistence between sarcoidosis and Sjogren's syndrome. Analysis of 43 patients

Imagem de Miniatura
Arquivos
art_FLORES-CHAVEZ_Characterisation_of_the_coexistence_between_sarcoidosis_and_Sjogrens_2022.PDF (1.6 MB)
Citações na Scopus
2
Tipo de produção
article
Data de publicação
2022
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
CLINICAL & EXPER RHEUMATOLOGY
Autores
FLORES-CHAVEZ, A.
NG, W-F
ALUNNO, A.
INANC, N.
FEIJOO-MASSO, C.
SEROR, R.
HERNANDEZ-MOLINA, G.
DEVAUCHELLE-PENSEC, V.
HOFAUER, B.
Citação
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, v.40, n.12, p.2329-2337, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective To characterise the key epidemiological, clinical, immunological, imaging, and pathological features of the coexistence between sarcoidosis and Sjogren's syndrome (SS). Methods All centres included in two large multicentre registries (the Sjogren Syndrome Big Data Consortium and the Sarco-GEAS-SEMI Registry) were contacted searching for potential cases of coexistence between SS and sarcoidosis seen in daily practice. Inclusion criteria were the fulfilment of the current classification criteria both for SS (2016 ACR/EULAR) and sarcoidosis (WASOG). The following features were considered for evaluating a coexisting immunopathological scenario between the two diseases: non-caseating granulomas (NCG), focal lymphocytic sialadenitis (FLS) and positive anti-Ro antibodies. Results We identified 43 patients who fulfilled the inclusion criteria (38 women, with a mean age of 53 years at diagnosis of SS and of 52 years at diagnosis of sarcoidosis). In 28 (65%) cases, sarcoidosis was diagnosed concomitantly with SS, or during the follow-up of patients with an already diagnosed SS, while in the remaining 15 (35%), SS was diagnosed during the follow-up of an already diagnosed sarcoidosis. Patients in whom sarcoidosis was diagnosed first showed a lower mean age (43.88 vs. 55.67 years, p=0.005) and were less frequently women (73% vs. 96%, p=0.04) in comparison with those in whom sarcoidosis was diagnosed concomitantly with SS, or during the follow-up of an already diagnosed SS. We identified the following immunopathological scenarios: a combination of NCG involving extrasalivary tissues and anti-Ro antibodies in 55% of patients, a coexistence of both pathological scenarios (extrasalivary NCG and FLS in MSGB) in 42% (with positive anti-Ro antibodies in two thirds of cases), and NCG involving salivary glands and anti-Ro antibodies in 3% of cases. Conclusion We have characterised the largest reported series of patients who fulfilled the current classification criteria for both SS and sarcoidosis. This implies that sarcoidosis (and not just the presence of isolated NCG on salivary gland biopsy) may, like other systemic autoimmune diseases, coexist with SS, and that a sarcoidosis diagnosis does not preclude the development of SS in the future.
Palavras-chave
sarcoidosis, Sjogren's syndrome, coexistence of autoimmune diseases
URI
https://observatorio.fm.usp.br/handle/OPI/54171
Referências
  1. Acar-Denizli N, 2019, CLIN EXP RHEUMATOL, V37, pS19
  2. Anaya JM, 2014, AUTOIMMUN REV, V13, P423, DOI 10.1016/j.autrev.2014.01.049
  3. Brito-Zeron P, 2019, CLIN EXP RHEUMATOL, V37, P1052
  4. Brito-Zeron P, 2021, JOINT BONE SPINE, V88, DOI 10.1016/j.jbspin.2021.105236
  5. Brito-Zeron P, 2020, RHEUMATOLOGY, V59, P2350, DOI 10.1093/rheumatology/kez578
  6. Brito-Zeron P, 2018, LUNG, V196, P239, DOI 10.1007/s00408-017-0076-4
  7. Brito-Zeron P, 2016, EXPERT OPIN PHARMACO, V17, P2431, DOI 10.1080/14656566.2016.1258061
  8. Brito-Zeron P, 2016, NAT REV DIS PRIMERS, V2, DOI 10.1038/nrdp.2016.47
  9. Cui David, 2020, Am J Ophthalmol Case Rep, V19, P100790, DOI 10.1016/j.ajoc.2020.100790
  10. Drosos AA, 1999, RHEUMATOL INT, V18, P177, DOI 10.1007/s002960050081
  11. Gal I, 2000, J RHEUMATOL, V27, P2507
  12. GIOTAKI H, 1986, RESPIRATION, V50, P102, DOI 10.1159/000194916
  13. Hansen SR, 2008, SCAND J RHEUMATOL, V37, P485, DOI 10.1080/03009740802220075
  14. Hernandez-Molina G, 2022, RHEUMATOLOGY, V62, P243, DOI 10.1093/rheumatology/keac205
  15. Inoue Y, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0143371
  16. Jimenez-Royo P, 2021, RHEUMATOLOGY, V60, P2396, DOI 10.1093/rheumatology/keaa624
  17. Judson MA, 2014, SARCOIDOSIS VASC DIF, V31, P19
  18. Keraen J, 2019, ARTHRITIS RHEUMATOL, V71, P1147, DOI 10.1002/art.40829
  19. Law ST, 2020, ARTHRIT CARE RES, V72, P1466, DOI 10.1002/acr.24029
  20. Lower EE, 2020, CLIN EXP RHEUMATOL, V38, P834
  21. Mansour MJ, 2007, J ORAL PATHOL MED, V36, P337, DOI 10.1111/j.1600-0714.2007.00530.x
  22. Mansour MJ, 2013, J ORAL PATHOL MED, V42, P594, DOI 10.1111/jop.12057
  23. Nakamura T, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.22827
  24. Perez-Alvarez R, 2019, EUR J INTERN MED, V69, P77, DOI 10.1016/j.ejim.2019.08.025
  25. Piekarski E, 2018, SEMIN NUCL MED, V48, P246, DOI 10.1053/j.semnuclmed.2018.02.005
  26. Ramos-Casals M, 2004, MEDICINE, V83, P85, DOI 10.1097/01.md.0000121237.98962.1e
  27. Ramos-Casals M, 2021, SCI REP-UK, V11, DOI 10.1038/s41598-021-92967-6
  28. Ramos-Casals M, 2020, ANN RHEUM DIS, V79, P3, DOI 10.1136/annrheumdis-2019-216114
  29. Ramos-Casals M, 2019, LUNG, V197, P427, DOI 10.1007/s00408-019-00243-2
  30. Ramos-Casals M, 2012, BMJ-BRIT MED J, V344, DOI [10.1136/bmj.e3821, 10.1024/1661-8157/a001133]
  31. Ramos-Casals M, 2015, RHEUMATOLOGY, V54, P2230, DOI 10.1093/rheumatology/kev200
  32. Retamozo S, 2021, CLIN EXP RHEUMATOL, V39, pS166
  33. ROSS JA, 1955, BRIT MED J, V2, P593, DOI 10.1136/bmj.2.4939.593
  34. Santiago T, 2014, RHEUMATOL INT, V34, P1619, DOI 10.1007/s00296-014-3024-0
  35. SCADDING JG, 1961, BRIT MED J, V2, P1165, DOI 10.1136/bmj.2.5261.1165
  36. Seror R, 2015, ANN RHEUM DIS, V74, P859, DOI 10.1136/annrheumdis-2013-204615
  37. Shiboski CH, 2017, ANN RHEUM DIS, V76, P9, DOI [10.1136/annrheumdis-2016-210571, 10.1002/art.39859]
  38. Terwiel M, 2019, CURR OPIN PULM MED, V25, P539, DOI 10.1097/MCP.0000000000000598
  39. Tokuyasu H, 2008, INTERNAL MED, V47, P2049, DOI 10.2169/internalmedicine.47.1526
  40. van de Loosdrecht AA, 2001, RHEUMATOLOGY, V40, P113, DOI 10.1093/rheumatology/40.1.113
  41. VITALI C, 1993, ARTHRITIS RHEUM, V36, P340, DOI 10.1002/art.1780360309
  42. Wu CH, 2017, J DERMATOL, V44, P423, DOI 10.1111/1346-8138.13654

Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/03
Artigos e Materiais de Revistas Científicas - LIM/17
Artigos e Materiais de Revistas Científicas - ODS/03