Association Between Triglycerides, High-Density Lipoprotein Cholesterol, and Their Ratio With the Pulse Wave Velocity in Adults From the ELSA-Brasil Study

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art_LELIS_Association_Between_Triglycerides_HighDensity_Lipoprotein_Cholesterol_and_Their_2023.PDF (860.37 KB)
Citações na Scopus
1
Tipo de produção
article
Data de publicação
2023
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SAGE PUBLICATIONS INC
Autores
LELIS, Deborah de Farias
CUNHA, Roberto S.
SPOSITO, Andrei C.
GRIEP, Rosane Harter
BARRETO, Sandhi Maria
MOLINA, Maria del Carmen B.
SCHMIDT, Maria Ines
DUNCAN, Bruce B.
Citação
ANGIOLOGY, v.74, n.9, p.822-831, 2023
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Atherogenic dyslipidemia is a risk factor for cardiovascular diseases. The present study aimed to evaluate the association between triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and the triglycerides to high-density lipoprotein (TG/HDL-C) ratio with carotid-femoral pulse wave velocity (cf-PWV), a marker of vascular stiffness. Anthropometric, biochemical, and clinical data from 13,732 adults were used to assess this association. Individuals within the third TG/HDL-C tertile presented worse anthropometric, biochemical, and clinical profiles as compared with the participants in the lower TG/HDL-C tertile. There was a linear association between TG, HDL-C, and TG/HDL-C ratio and cf-PWV in both men and women (stronger in women). After adjustment for confounders, lower levels of HDL-C were associated with increased cf-PWV in men (9.63 +/- .02 m/s) and women (8.90 +/- .03 m/s). However, TG was not significantly associated with cf-PWV after adjustment, regardless of sex. An increased TG/HDL-C ratio is associated with higher cf-PWV only in women (9.01 +/- .03 m/s), but after adjustment for HDL-C levels, the association was non-significant (8.99 +/- .03 m/s). These results highlight the stronger association of HDL-C with arterial stiffness, and that the association of TG/HDL-C with cf-PWV is dependent on HDL-C.
Palavras-chave
arterial stiffness, triglycerides, high-density lipoprotein cholesterol, triglycerides, high-density lipoprotein cholesterol ratio
URI
https://observatorio.fm.usp.br/handle/OPI/56026
Referências
  1. Alagona C, 2003, EUR J CLIN INVEST, V33, P457, DOI 10.1046/j.1365-2362.2003.01165.x
  2. Alvim Rafael de Oliveira, 2017, Int. J. Cardiovasc. Sci., V30, P433, DOI 10.5935/2359-4802.20170053
  3. Alvim RD, 2017, CLINICS, V72, P106, DOI 10.6061/clinics/2017(02)07
  4. Amar J, 2001, J HYPERTENS, V19, P381, DOI 10.1097/00004872-200103000-00005
  5. Anderson SG, 2009, HYPERTENSION, V53, P839, DOI 10.1161/HYPERTENSIONAHA.108.123885
  6. Aquino EML, 2012, AM J EPIDEMIOL, V175, P315, DOI 10.1093/aje/kwr294
  7. Aznaouridis K, 2007, HEART, V93, P613, DOI 10.1136/hrt.2006.095554
  8. Baldo MP, 2017, J AM HEART ASSOC, V6, DOI 10.1161/JAHA.117.005477
  9. Baldo MP, 2018, INT J CARDIOL, V251, P90, DOI 10.1016/j.ijcard.2017.10.075
  10. Benetos A, 2002, CIRCULATION, V105, P1202, DOI 10.1161/hc1002.105135
  11. Botham KM, 2007, BIOCHEM SOC T, V35, P454, DOI 10.1042/BST0350454
  12. Catapano AL, 2016, EUR HEART J, V37, P2999, DOI 10.1093/eurheartj/ehw272
  13. Cecelja M, 2009, HYPERTENSION, V54, P1328, DOI 10.1161/HYPERTENSIONAHA.109.137653
  14. Chang JB, 2011, LIPIDS HEALTH DIS, V10, DOI 10.1186/1476-511X-10-228
  15. Chen C, 2018, LIPIDS HEALTH DIS, V17, DOI 10.1186/s12944-018-0776-7
  16. Dart AM, 2004, ARTERIOSCL THROM VAS, V24, P962, DOI 10.1161/01.ATV.0000126371.14332.ab
  17. Ference BA, 2018, CARDIOL CLIN, V36, P203, DOI 10.1016/j.ccl.2017.12.001
  18. Fruchart JC, 2019, CARDIOVASC DIABETOL, V18, DOI 10.1186/s12933-019-0864-7
  19. Havlik RJ, 2001, AM J CARDIOL, V87, P104, DOI 10.1016/S0002-9149(00)01282-0
  20. Helkin A, 2016, VASC ENDOVASC SURG, V50, P107, DOI 10.1177/1538574416628654
  21. Lamarche B, 1999, J CLIN INVEST, V103, P1191, DOI 10.1172/JCI5286
  22. Lebrun CEI, 2002, J HYPERTENS, V20, P2165, DOI 10.1097/00004872-200211000-00015
  23. Lelis DD, 2021, J CLIN LIPIDOL, V15, P699, DOI 10.1016/j.jacl.2021.07.005
  24. MATTHEWS DR, 1985, DIABETOLOGIA, V28, P412, DOI 10.1007/BF00280883
  25. McEniery CM, 2010, HYPERTENSION, V56, P36, DOI 10.1161/HYPERTENSIONAHA.110.150896
  26. McLaughlin T, 2003, ANN INTERN MED, V139, P802, DOI 10.7326/0003-4819-139-10-200311180-00007
  27. Miao DM, 2011, J CLIN HYPERTENS, V13, P710, DOI 10.1111/j.1751-7176.2011.00501.x
  28. Mill JG, 2013, REV SAUDE PUBL, V47, P54, DOI 10.1590/S0034-8910.2013047003851
  29. Millán J, 2009, VASC HEALTH RISK MAN, V5, P757
  30. Miller M, 2011, CIRCULATION, V123, P2292, DOI 10.1161/CIR.0b013e3182160726
  31. Mitchell GF, 2004, HYPERTENSION, V43, P1239, DOI 10.1161/01.HYP.0000128420.01881.aa
  32. Murguía-Romero M, 2013, J LIPID RES, V54, P2795, DOI 10.1194/jlr.M040584
  33. Nakanishi N, 2005, HYPERTENS RES, V28, P125, DOI 10.1291/hypres.28.125
  34. Palmisano BT, 2018, MOL METAB, V15, P45, DOI 10.1016/j.molmet.2018.05.008
  35. Pascot A, 2002, ATHEROSCLEROSIS, V160, P399, DOI 10.1016/S0021-9150(01)00579-2
  36. Roes SD, 2008, DIABETES CARE, V31, P1442, DOI 10.2337/dc08-0055
  37. Roth GA, 2020, J AM COLL CARDIOL, V76, P2982, DOI 10.1016/j.jacc.2020.11.010
  38. Salazar MR, 2014, J AM SOC HYPERTENS, V8, P724, DOI 10.1016/j.jash.2014.08.002
  39. Schmidt MI, 2015, INT J EPIDEMIOL, V44, P68, DOI 10.1093/ije/dyu027
  40. Shen WC, 2017, NUTR METAB CARDIOVAS, V27, P1136, DOI 10.1016/j.numecd.2017.10.003
  41. Shimizu Y, 2013, ATHEROSCLEROSIS, V228, P491, DOI 10.1016/j.atherosclerosis.2013.03.021
  42. Shin HG, 2017, KOREAN J FAM MED, V38, P352, DOI 10.4082/kjfm.2017.38.6.352
  43. Shuhei N, 2010, LIPIDS HEALTH DIS, V9, DOI 10.1186/1476-511X-9-104
  44. TALL AR, 1995, J INTERN MED, V237, P5, DOI 10.1111/j.1365-2796.1995.tb01133.x
  45. Tanaka H, 2009, J HYPERTENS, V27, P2022, DOI 10.1097/HJH.0b013e32832e94e7
  46. Tilly-Kiesi M, 1997, ARTERIOSCL THROM VAS, V17, P3513, DOI 10.1161/01.ATV.17.12.3513
  47. Tsioufis C, 2008, J HYPERTENS, V26, P773, DOI 10.1097/HJH.0b013e3282f430b0
  48. Urbina EM, 2013, PEDIATRICS, V131, pE1082, DOI 10.1542/peds.2012-1726
  49. Vallée A, 2019, J HYPERTENS, V37, P2240, DOI 10.1097/HJH.0000000000002161
  50. Veronese FV, 2014, CLIN CHEM LAB MED, V52, P1747, DOI 10.1515/cclm-2014-0052
  51. Vlachopoulos C, 2010, J AM COLL CARDIOL, V55, P1318, DOI 10.1016/j.jacc.2009.10.061
  52. Wang F, 2011, EUR J CLIN INVEST, V41, P929, DOI 10.1111/j.1365-2362.2011.02481.x
  53. Wang X, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0081778
  54. Wang XN, 2016, LIPIDS HEALTH DIS, V15, DOI 10.1186/s12944-016-0266-8
  55. Wen JH, 2015, INT J CLIN EXP MED, V8, P4342
  56. Wen JH, 2017, J CLIN HYPERTENS, V19, P771, DOI 10.1111/jch.13038
  57. Zitnanova I, 2020, CLIN BIOCHEM, V79, P9, DOI 10.1016/j.clinbiochem.2020.02.002

Coleções
Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/20
Artigos e Materiais de Revistas Científicas - ODS/03