Departamento de Psiquiatria - FM/MPS

O Departamento de Psiquiatria da Faculdade de Medicina da Universidade de São Paulo (FMUSP) abrange as áreas de Graduação, Internato, Residência Médica, Pós-Graduação lato sensu e Pós-Graduação stricto sensu, bem como estágios de curta e longa duração para profissionais médicos e de áreas afins. Na graduação, responde por um módulo de Psiquiatria na disciplina de Bases Fisiológicas da Clínica Médica e pelas disciplinas de Bases Humanísticas da Medicina, Psicologia Médica e Psiquiatria Clínica.

Além de atuar nas áreas de ensino e assistência, tem alta produtividade científica na FMUSP, exercendo liderança nacional de pesquisas básica e clínica em áreas de transtornos do humor, transtornos de ansiedade, esquizofrenia, psiquiatria geriátrica, genética e epidemiologia, além de liderar grupos nacionais de pesquisa, como o Consórcio Brasileiro de Pesquisa dos Transtornos do Espectro Obsessivo-Compulsivo (C-TOC).

Site: http://ipqhc.org.br/

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Recent Submissions

  1. Textual Inference Comprehension in Mild Cognitive Impairment: The Influence of Semantic Processing and Verbal Episodic Memory

    FRONTIERS IN AGING NEUROSCIENCE, v.13, article ID 735633, 10p, 2021

    Language complaints, especially in complex tasks, may occur in mild cognitive impairment (MCI). Various language measures have been studied as cognitive predictors of MCI conversion to Alzheimer's type dementia. Understanding textual inferences is considered a high-demanding task that recruits mu...

  2. Cellular and Extracellular White Matter Abnormalities in Obsessive-Compulsive Disorder: A Diffusion Magnetic Resonance Imaging Study

    BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING, v.6, n.10, p.983-991, 2021

    BACKGROUND: While previous studies have implicated white matter (WM) as a core pathology of obsessive compulsive disorder (OCD), the underlying neurobiological processes remain elusive. This study used free-water (FW) imaging derived from diffusion magnetic resonance imaging to identify cellular ...

  3. Cortical surface abnormalities are different depending on the stage of schizophrenia: A cross-sectional vertexwise mega-analysis of thickness, area and gyrification

    SCHIZOPHRENIA RESEARCH, v.236, p.104-114, 2021

    Background: Brain magnetic resonance imaging studies have not investigated the cortical surface comprehensively in schizophrenia subjects by assessing thickness, surface area and gyrification separately during the first episode of psychosis (FEP) or chronic schizophrenia (ChSch). Methods: We inve...

  4. Two novel pathogenic variants in MED13L: one familial and one isolated case

    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, v.65, n.12, p.1049-1057, 2021

    Background Genetic variants involving the MED13L gene can lead to an autosomal dominant syndrome characterised by intellectual disability/developmental delay and facial dysmorphism. Methods We investigated two cases (one familial and one isolated) of intellectual disability with speech delay and ...

  5. How do daily routines and situational factors affect the severity of obsessive-compulsive disorder?

    JOURNAL OF PSYCHIATRIC RESEARCH, v.143, p.395-399, 2021

    Background: Daily routine and situations may worsen, stabilise, or improve symptoms of obsessive-compulsive disorder (OCD). We investigated which factors OCD patients perceived to be related to the worsening of their OCD symptoms and their relationship to patients' OCD symptom severity. Methods: ...

  6. The impact of child psychiatric conditions on future educational outcomes among a community cohort in Brazil

    EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES, v.30, article ID e69, 10p, 2021

    Aims Mental health problems early in life can negatively impact educational attainment, which in turn have negative long-term effects on health, social and economic opportunities. Our aims were to: (i) estimate the impacts of different types of psychiatric conditions on educational outcomes and (...

  7. Which are the best evidence-based therapeutic options for clozapine and ECT resistant schizophrenia? A case-report

    PSYCHIATRY RESEARCH, v.305, article ID 114248, 3p, 2021

    This is a case description of a patient with clozapine and ECT resistance schizophrenia with several suicide attempts. We discussed evidence-based clinical decisions to deal with such conditions.

  8. Brain areas involved with obsessive-compulsive disorder present different DNA methylation modulation

    BMC GENOMIC DATA, v.22, n.1, article ID 45, 18p, 2021

    Background Obsessive-compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive actions, that presents the involvement of the cortico-striatal areas. The contribution of environmental risk factors to OCD development suggests that epigenetic mechanisms may contribute to its pa...

  9. Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.115, n.22, p.E5154-E5163, 2018

    Hemispheric asymmetry is a cardinal feature of human brain organization. Altered brain asymmetry has also been linked to some cognitive and neuropsychiatric disorders. Here, the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium presents the largest-ever analysis of cerebra...

  10. In vivo imaging evidence of poor cognitive resilience to Alzheimer's disease pathology in subjects with very low cognitive reserve from a low-middle income environment

    ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING, v.12, n.1, article ID e12122, 11p, 2020

    INTRODUCTION: Reduced cognitive reserve (CR) due to very low educational (VLE) levels may influence high dementia rates in low-middle income environments, leading to decreased cognitive resilience (RES) to Alzheimers disease (AD) pathology. However, in vivo findings in VLE groups confirming this ...