• Clinical patterns differentially predict response to transcranial direct current stimulation (tDCS) and escitalopram in major depression: A machine learning analysis of the ELECT-TDCS study 

  KAMBEITZ, Joseph; GOERIGK, Stephan; GATTAZ, Wagner; FALKAI, Peter; BENSENOR, Isabela M.; LOTUFO, Paulo A.; BUEHNER, Markus; KOUTSOULERIS, Nikolaos; PADBERG, Frank; BRUNONI, Andre R. (ELSEVIER, AMSTERDAM, NETHERLANDS, 2020)
• Reduced Annexin A3 in schizophrenia 

  JOAQUIM, Helena P. G.; COSTA, Alana Caroline; SERPA, Mauricio Henriques; TALIB, Leda L.; GATTAZ, Wagner F. (SPRINGER HEIDELBERG, HEIDELBERG, GERMANY, 2020)

  The cellular and molecular mechanisms underlying onset and development of schizophrenia have not yet been completely elucidated, but the association of disturbed neuroplasticity and inflammation has gained particular ...
• Passive antiamyloid immunotherapy for Alzheimer's disease 

  LOUREIRO, Julia C.; PAIS, Marcos V.; STELLA, Florindo; RADANOVIC, Marcia; TEIXEIRA, Antonio Lucio; FORLENZA, Orestes V.; SOUZA, Leonardo Cruz de (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)

  Purpose of review Antiamyloid therapy of Alzheimer's disease tackles the overproduction and clearance of the amyloid-beta peptide (A beta). Immunotherapeutic compounds were tested in large-scale trials. We revisit the ...
• The neuroscience of sadness: A multidisciplinary synthesis and collaborative review 

  ARIAS, Juan A.; WILLIAMS, Claire; RAGHVANI, Rashmi; AGHAJANI, Moji; BAEZ, Sandra; BELZUNG, Catherine; BOOIJ, Linda; BUSATTO, Geraldo; CHIARELLA, Julian; FU, Cynthia H. Y.; IBANEZ, Agustin; LIDDELL, Belinda J.; LOWE, Leroy; PENNINX, Brenda W. J. H.; ROSA, Pedro; KEMP, Andrew H. (PERGAMON-ELSEVIER SCIENCE LTD, OXFORD, ENGLAND, 2020)

  Sadness is typically characterized by raised inner eyebrows, lowered corners of the mouth, reduced walking speed, and slumped posture. Ancient subcortical circuitry provides a neuroanatomical foundation, extending from ...
• Gene expression changes associated with trajectories of psychopathology in a longitudinal cohort of children and adolescents 

  OTA, Vanessa Kiyomi; SANTORO, Marcos Leite; SPINDOLA, Leticia Maria; PAN, Pedro Mario; SIMABUCURO, Andressa; XAVIER, Gabriela; VIEIRA-FONSECA, Tamiris; ZANARDO, Evelin Aline; SANTOS, Felipe Rodolfo Camargo dos; SCHAFER, Julia Luiza; KULIKOWSKI, Leslie Domenici; GALANTE, Pedro A. F.; ASPRINO, Paula Fontes; BRIETZKE, Elisa; GRASSI-OLIVEIRA, Rodrigo; ROHDE, Luis Augusto; MIGUEL, Euripedes Constantino; GADELHA, Ary; MARI, Jair Jesus; BRESSAN, Rodrigo Affonseca; SALUM, Giovanni Abrahao; BELANGERO, Sintia Iole (NATURE PUBLISHING GROUP, LONDON, ENGLAND, 2020)

  We aimed to identify blood gene expression patterns associated to psychopathological trajectories retrieved from a large community, focusing on the emergence and remission of general psychiatric symptoms. Hundred and three ...
• Abstinence and retention outcomes in a smoking cessation program among individuals with co-morbid substance use and mental disorders 

  LIMA, Danielle Ruiz; CARVALHO, Carlos Felipe Cavalcanti; GUIMARAES-PEREIRA, Bruna Beatriz Sales; LORETO, Aline Rodrigues; FRALLONARDO, Fernanda Piotto; ISMAEL, Flavia; ANDRADE, Arthur Guerra de; CASTALDELLI-MAIA, Joao Mauricio (PERGAMON-ELSEVIER SCIENCE LTD, OXFORD, ENGLAND, 2020)

  Tobacco use is the leading cause of preventable death in the world. Although cigarette smoking prevalence has decreased, there are still disparities in morbidity and mortality experienced by individuals with substance use ...
• A randomized controlled trial of social skills training for patients with treatment-resistant schizophrenia with predominantly negative symptoms 

  KAYO, Monica; SCEMES, Silvia; SAVOIA, Mariangela Gentil; BICHUETTE, Alice; ABREU, Ana Claudia; SILVA, Emily Pereira dA; BARIA, Patricia; PIOVACCARI, Victoria; PETRECHE, Beatriz; BRESSAN, Rodrigo Affonseca; GADELHA, Ary; ELKIS, Helio (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2020)

  We conducted a randomized controlled trial to assess the effectiveness of social skills training (SST) in improving negative symptoms in patients with treatment-resistant schizophrenia with predominantly negative symptoms. ...
• Three plasma metabolites in elderly patients differentiate mild cognitive impairment and Alzheimer's disease: a pilot study 

  COSTA, Alana C.; JOAQUIM, Helena P. G.; V, Orestes Forlenza; GATTAZ, Wagner F.; TALIB, Leda L. (SPRINGER HEIDELBERG, HEIDELBERG, GERMANY, 2020)

  The metabolomic profile of patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) may suggest potential diagnostic biomarkers and provide information on the pathophysiology of dementia. Our aim was to ...
• Gambling disorder and comorbid behavioral addictions: Demographic, clinical, and personality correlates 

  TANG, Karen T. Y.; KIM, Hyoun S.; HODGINS, David C.; MCGRATH, Daniel S.; TAVARES, Hermano (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2020)

  Gambling disorder (GD) frequently co-occurs with substance use disorders. However, the extent to which GD co-occurs with behavioral addictions (BAs) and the demographic, clinical, and personality correlates of comorbid GD ...
• Two distinc neuroanatomica subtypes of schizophrenia revealed using machine learning 

  CHAND, Ganesh B.; DWYER, Dominic B.; ERUS, Guray; SOTIRAS, Aristeidis; VAROL, Erdem; SRINIVASAN, Dhivya; DOSHI, Jimit; POMPONIO, Raymond; PIGONI, Alessandro; DAZZAN, Paola; KAHN, Rene S.; SCHNACK, Hugo G.; ZANETTI, Marcus V.; MEISENZAHL, Eva; BUSATTO, Geraldo F.; CRESPO-FACORRO, Benedicto; PANTELIS, Christos; WOOD, Stephen J.; ZHUO, Chuanjun; SHINOHARA, Russell T.; SHOU, Haochang; FAN, Yong; GUR, Ruben C.; GUR, Raquel E.; SATTERTHWAITE, Theodore D.; KOUTSOULERIS, Nikolaos; WOLF, Daniel H.; DAVATZIKOS, Christos (OXFORD UNIV PRESS, OXFORD, ENGLAND, 2020)

  Neurobiological heterogeneity in schizophrenia is poorly understood and confounds current analyses. We investigated neuroanatomical subtypes in a multi-institutional multi-ethnic cohort, using novel semi-supervised machine ...
• Distinct effects of cocaine and cocaine + cannabis on neurocognitive functioning and abstinence: A six-month follow-up study (vol 205, 107642, 2019) 

  OLIVEIRA JUNIOR, Hercilio Pereira de; GONCALVES, Priscila Dib; OMETTO, Mariella; SANTOS, Bernardo dos; MALBERGIER, Andre; AMARAL, Ricardo; NICASTRI, Sergio; ANDRADE, Arthur Guerra de; CUNHA, Paulo Jannuzzi (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2020)
• Independent and interactive associations of temperament dimensions with educational outcomes in young adolescents 

  HOFFMANN, Mauricio Scopel; PAN, Pedro Mario; MANFRO, Gisele Gus; MARI, Jair de Jesus; MIGUEL, Euripedes Constantino; BRESSAN, Rodrigo Affonseca; ROHDE, Luis Augusto; SALUM, Giovanni Abrahao (ELSEVIER, AMSTERDAM, NETHERLANDS, 2020)

  Few studies investigate temperament interactions and its association with education in young adolescents. Here we examine a sample of 1540 adolescents (9-14 years of age, 733 females) from a community-based study in Brazil. ...
• A 12-Week Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Topiramate for the Treatment of Compulsive Buying Disorder 

  MATTOS, Cristiana de; KIM, Hyoun S.; MARASALDI, Renata F.; REQUIAO, Marinalva G.; OLIVEIRA, Elen Cristina de; FILOMENSKY, Tatiana; TAVARES, Hermano (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)

  Background Topiramate is an anticonvulsant that has shown promise as a pharmacological agent for the treatment of addictive disorders, including compulsive buying disorder (CBD). The aim of the present study was to examine ...
• Gender Differences in Gambling Exposure and At-risk Gambling Behavior 

  CARNEIRO, Elizabeth; TAVARES, Hermano; SANCHES, Marcos; PINSKY, Ilana; CAETANO, Raul; ZALESKI, Marcos; LARANJEIRA, Ronaldo (SPRINGER, NEW YORK, UNITED STATES, 2020)

  This study aimed to evaluate the differences in gambling exposure and onset of gambling problems among male and female gamblers by comparing their demographic and behavioral profiles. This study utilized data from the ...
• Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial 

  BRUNONI, Andre R.; CARRACEDO, Angel; AMIGO, Olalla M.; PELLICER, Ana L.; TALIB, Leda; CARVALHO, Andre F.; LOTUFO, Paulo A.; BENSENOR, Isabela M.; GATTAZ, Wagner; CAPPI, Carolina (ASSOC BRASILEIRA PSIQUIATRIA, SAO PAULO, BRAZIL, 2020)

  Objective: We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the ...
• Spirituality, religiosity and addiction recovery: Current perspectives 

  BERALDO, L.; GIL, F.; VENTRIGLIO, A.; ANDRADE, A.G. de; SILVA, A.G. da; TORALES, J.; GONçALVES, P.D.; BHUGRA, D.; CASTALDELLI-MAIA, J.M. (BENTHAM SCIENCE PUBLISHERS B.V., 2019)

  Substance use disorders are an important public health problem with a multifactorial etiology and limited effective treatment options. Within this context, spirituality-based approaches may provide interesting and useful ...
• The Superiority of Tsallis Entropy over Traditional Cost Functions for Brain MRI and SPECT Registration 

  AMARAL-SILVA, Henrique; WICHERT-ANA, Lauro; MURTA, Luiz Otavio; ROMUALDO-SUZUKI, Larissa; ITIKAWA, Emerson; BUSSATO, Geraldo Filho; AZEVEDO-MARQUES, Paulo (MDPI, BASEL, SWITZERLAND, 2014)

  Neuroimage registration has an important role in clinical (for both diagnostic and therapeutic purposes) and research applications. In this article we describe the applicability of Tsallis Entropy as a new cost function ...
• Child and adolescent psychiatry training in Brazil, Argentina, Uruguay and Chile: current panorama and future challenges 

  SCIVOLETTO, Sandra; FONDELLO, Marina A.; OTOCH, Luara N.; CELERI, Eloisa H. R. Valler; CAETANO, Sheila C.; GRAEFF-MARTINS, Ana Soledade; ROSARIO, Maria Conceicao; PALLIA, Roberto; GUTIERREZ, Adriana; VALDIVIA, Mario; VIOLA, Laura; POLANCZYK, Guilherme V. (SPRINGER, NEW YORK, UNITED STATES, 2020)

  Mental disorders affect approximately 10-15% of children and adolescents worldwide. In South America these numbers are probably higher due to poverty and adverse life events that frequently affect this region. The availability ...
• Clinical and biological effects of long-term lithium treatment in older adults with amnestic mild cognitive impairment: randomised clinical trial 

  FORLENZA, Orestes V.; RADANOVIC, Marcia; TALIB, Leda L.; GATTAZ, Wagner F. (CAMBRIDGE UNIV PRESS, CAMBRIDGE, ENGLAND, 2019)

  Background Experimental studies indicate that lithium may facilitate neurotrophic/protective responses in the brain. Epidemiological and imaging studies in bipolar disorder, in addition to a few trials in Alzheimer's disease ...
• Attention-deficit hyperactivity disorder 

  POSNER, Jonathan; POLANCZYK, Guilherme V.; SONUGA-BARKE, Edmund (ELSEVIER SCIENCE INC, NEW YORK, USA, 2020)

  Attention-deficit hyperactivity disorder (ADHD), like other psychiatric disorders, represents an evolving construct that has been refined and developed over the past several decades in response to research into its clinical ...

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