Improvement of verbal fluency in patients with diffuse brain injury over time

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art_ZANINOTTO_Improvement_of_verbal_fluency_in_patients_with_diffuse_2014.PDF (168.16 KB)
Citações na Scopus
10
Tipo de produção
article
Data de publicação
2014
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
DOVE MEDICAL PRESS LTD
Autores
NUNES, Monica Domiano
Citação
NEUROPSYCHIATRIC DISEASE AND TREATMENT, v.10, p.1155-1160, 2014
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Diffuse axonal injury (DAI), a common cause of neurological sequelae in patients with traumatic brain injury (TBI), is considered one of the most prevalent forms of primary neuronal injury in patients with severe TBI. Cognitive deficits induced by DAI can persist over time, especially following moderate or severe injuries. The aim of the present study was to compare verbal fluency (VF) performance at 6 and 12 months after the trauma in a same group of patients with DAI. Methods: Eighteen patients with moderate to severe DAI and 17 healthy volunteers were enrolled. All DAI participants had sustained a TBI at least 6 months prior to the start of the study, were between 18 and 50 years of age, and had at least 4 years of education. The VF test was administered within an extensive neuropsychological test battery. We evaluated the same patients at 6 months (DAI1 group) and 12 months (DAI2 group) and compared the results of neuropsychological tests with a control group of healthy volunteers who were matched to patients for sex, age, and educational level. Results: In comparison to controls, the DAI1 group produced significantly fewer words. The DAI2 group produced significantly more semantic words than DAI1 (P<0.05) and demonstrated a trend towards the production of more clusters for letter A (P=0.09) and total words generated in a phonemic test (P=0.09). No significant differences were observed between DAI2 and the control group in the total number of words generated in phonetic FAS or semantic fluency scores. Conclusion: The present findings may be useful in the construction of a management plan for long-term TBI rehabilitation that considers the trauma of each patient. Further, our results suggest the VF test is a suitable instrument for the assessment of cognitive difficulties following TBI.
Palavras-chave
traumatic brain injury, neuropsychological tests, diffuse axonal injury, prognosis, executive function
URI
https://observatorio.fm.usp.br/handle/OPI/7552
Referências
  1. Andrade Almir Ferreira de, 2011, Arq Neuropsiquiatr, V69, P79
  2. Andrade Almir Ferreira de, 2009, Rev Assoc Med Bras, V55, P75
  3. Bashir S, 2012, RESTOR NEUROL NEUROS, V30, P277, DOI 10.3233/RNN-2012-110207
  4. Bercaw EL, 2011, CLIN NEUROPSYCHOL, V25, P72, DOI 10.1080/13854046.2010.532813
  5. Busch RM, 2005, J CLIN EXP NEUROPSYC, V27, P1022, DOI 10.1080/13803390490919263
  6. De Capitani EM, 2005, CLIN TOXICOL, V43, P287, DOI 10.1081/CLT-200058934
  7. Dikmen SS, 2009, J HEAD TRAUMA REHAB, V24, P430, DOI 10.1097/HTR.0b013e3181c133e9
  8. Dikmen SS, 2003, ARCH PHYS MED REHAB, V84, P1449, DOI 10.1016/S0003-9993(03)00287-9
  9. Henry JD, 2004, NEUROPSYCHOLOGY, V18, P284, DOI 10.1037/0894-4105.18.2.284
  10. Jurado MA, 2000, BRAIN INJURY, V14, P789
  11. Kave G, 2005, J CLIN EXP NEUROPSYC, V27, P690, DOI 10.1080/13803390490918499
  12. Kave G, 2011, J CLIN EXP NEUROPSYC, V33, P358, DOI 10.1080/13803395.2010.518703
  13. Lezak MD, 2004, NEUROPSYCHOLOGICAL A
  14. Lima DPD, 2008, INJURY, V39, P604, DOI 10.1016/j.injury.2007.11.008
  15. Mathias JL, 2004, APPL NEUROPSYCHOL, V11, P134, DOI 10.1207/s15324826an1103_2
  16. Rich JB, 1999, NEUROPSYCHOLOGY, V13, P525, DOI 10.1037/0894-4105.13.4.525
  17. Robert PH, 1998, J INT NEUROPSYCH SOC, V4, P539
  18. Troster AI, 1998, NEUROPSYCHOLOGIA, V36, P295, DOI 10.1016/S0028-3932(97)00153-X
  19. Troyer AK, 1998, J INT NEUROPSYCH SOC, V4, P137, DOI 10.1017/S1355617798001374
  20. Troyer AK, 2000, J CLIN EXP NEUROPSYC, V22, P370, DOI 10.1076/1380-3395(200006)22:3;1-V;FT370
  21. Troyer AK, 1998, NEUROPSYCHOLOGIA, V36, P499, DOI 10.1016/S0028-3932(97)00152-8
  22. Troyer AK, 1997, NEUROPSYCHOLOGY, V11, P138, DOI 10.1037//0894-4105.11.1.138
  23. Vakil E, 2005, J CLIN EXP NEUROPSYC, V27, P977, DOI 10.1080/13803390490919245
  24. Wilson BA, 2000, J INT NEUROPSYCH SOC, V6, P469
  25. Zakzanis KK, 2011, J CLIN EXP NEUROPSYC, V33, P785, DOI 10.1080/13803395.2011.558496
  26. Zakzanis KK, 2013, BRAIN INJURY, V27, P903, DOI 10.3109/02699052.2013.775505

Coleções
Artigos e Materiais de Revistas Científicas - FM/MNE
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/26