Hemispheric dorsolateral prefrontal cortex lateralization in the regulation of empathy for pain
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Citações na Scopus
48
Tipo de produção
article
Data de publicação
2015
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER IRELAND LTD
Autores
REGO, Gabriel G.
LAPENTA, Olivia M.
MARQUES, Lucas M.
COSTA, Thiago L.
LEITE, Jorge
CARVALHO, Sandra
GONCALVES, Oscar F.
FREGNI, Felipe
BOGGIO, Paulo S.
Citação
NEUROSCIENCE LETTERS, v.594, p.12-16, 2015
Resumo
The dorsolateral prefrontal cortex (DLPFC) is involved in the cognitive appraisal and modulation of the pain experience. In this sham-controlled study, with healthy volunteers, we used bi-hemispheric transcranial direct current stimulation (tDCS) over the DLPFC to assess emotional reactions elicited by pain observation. Left-cathodal/right-anodal tDCS decreased valence and arousal evaluations compared to other tDCS conditions. Compared to sham condition, both left-cathodal/right-anodal and left-anodal/right-cathodal tDCS decreased hostility, sadness and self-pain perception. These decreased sensations after both active tDCS suggest a common role for left and right DLPFC in personal distress modulation. However, the differences in arousal and valence evaluations point to distinct roles of lateralized DLPFC in cognitive empathy, probably through distinct emotion regulation mechanisms.
Palavras-chave
Physical pain, Pain empathy, Emotion regulation, Dorsolateral prefrontal cortex, Transcranial direct current stimulation, Pupil dilation
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