Nonverbal behaviors are associated with increased vagal activity in major depressive disorder: Implications for the polyvagal theory

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art_FERNANDES_Nonverbal_behaviors_are_associated_with_increased_vagal_activity_2017.PDF (275.47 KB)
Citações na Scopus
4
Tipo de produção
article
Data de publicação
2017
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCIENCE BV
Autores
FERNANDES, Raquel A.
DANTAS, Eduardo Miranda
CARVALHO, Andre F.
Citação
JOURNAL OF AFFECTIVE DISORDERS, v.209, p.18-22, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Major depressive disorder (MDD) is associated with impairments in nonverbal behaviors (NVBs) and vagal activity. The polyvagal theory proposes that vagal activity regulates heart rate and NVBs by modulating a common anatomically and neurophysiologically discrete social engagement system. However, the association between these putative endophenotypes has not yet been explored. We hypothesize that in MDD, NVBs indicating positive affects and social interest and those indicating negative feelings and social disinterest could be associated with different patterns of vagal activity. Methods: For this cross-sectional study we recruited 50 antidepressant-free participants with moderate-to-severe MDD. Vagal activity was indexed by heart rate variability (HRV) measures, and positive and negative nonverbal behaviors (NVBs) by a validated ethogram. Associations between NVBs and HRV were explored by bivariate analyses and multivariable models were adjusted by age, gender, depression severity, and self-reported positive and negative affects. Results: HRV measures indicative of higher vagal activity were positively correlated with positive NVBs exhibited during the clinical interview. Conversely, NVBs related to negative affects, low energy and social disinterest were not associated with HRV. Limitations: Absence of a control group. Conclusions: The findings highlight that the examined depression endophenotypes (nonverbal behaviors and vagal activity) are related, shedding light on MDD pathophysiology in the context of the polyvagal theory.
Palavras-chave
Major depressive disorder, Heart rate variability, Vagal activity, Nonverbal behavior, Ethogram, Psychiatry
URI
https://observatorio.fm.usp.br/handle/OPI/18941
Referências
  1. Annen S, 2012, J NERV MENT DIS, V200, P26, DOI 10.1097/NMD.0b013e31823e653b
  2. Appelhans BM, 2008, BIOL PSYCHOL, V77, P174, DOI 10.1016/j.biopsycho.2007.10.004
  3. Brunoni AR, 2015, SAO PAULO MED J, V133, P252, DOI 10.1590/1516-3180.2014.00351712
  4. Craig CL, 2003, MED SCI SPORT EXER, V35, P1381, DOI 10.1249/01.MSS.0000078924.61453.FB
  5. Daubert DL, 2012, J PHYSIOL-LONDON, V590, P4881, DOI 10.1113/jphysiol.2012.232314
  6. Reyes Del Paso G.A., 2013, PSYCHOPHYSIOLOGY
  7. Eckberg DL, 1997, CIRCULATION, V96, P3224
  8. Fiquer JT, 2013, J AFFECT DISORDERS, V150, P1114, DOI 10.1016/j.jad.2013.05.002
  9. Girard JM, 2014, IMAGE VISION COMPUT, V32, P641, DOI 10.1016/j.imavis.2013.12.007
  10. Gorenstein C, 1996, BRAZ J MED BIOL RES, V29, P453
  11. Jandackova VK, 2016, PSYCHOL MED, V46, P2121, DOI 10.1017/S003329171600060X
  12. Kemp A.H., 2014, AM J PSYCHIAT
  13. Kemp AH, 2010, BIOL PSYCHIAT, V67, P1067, DOI 10.1016/j.biopsych.2009.12.012
  14. Kikuchi M, 2009, PROG NEURO-PSYCHOPH, V33, P1474, DOI 10.1016/j.pnpbp.2009.08.002
  15. MALLIANI A, 1991, CIRCULATION, V84, P482
  16. Porges S. W., 2011, POLYVAGAL THEORY NEU
  17. Quintana DS, 2016, TRANSL PSYCHIAT, V6, DOI 10.1038/tp.2016.73
  18. Thayer JF, 2009, ANN BEHAV MED, V37, P141, DOI 10.1007/s12160-009-9101-z
  19. Verrier R.L., 2011, PRINCIPLES PRACTICE
  20. Wilson ST, 2016, PSYCHIAT RES, V240, P241, DOI 10.1016/j.psychres.2016.04.033

Coleções
Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/20
Artigos e Materiais de Revistas Científicas - LIM/21
Artigos e Materiais de Revistas Científicas - LIM/23
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