Outbreak of carbapenem-resistant Klebsiella pneumoniae: two-year epidemiologic follow-up in a tertiary hospital

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art_LEVIN_Outbreak_of_carbapenem_resistant_Klebsiella_pneumoniae_two_year_2013.PDF (327.64 KB)
Citações na Scopus
10
Tipo de produção
article
Data de publicação
2013
DOI
SciELO
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
FUNDACO OSWALDO CRUZ
Autores
PEREIRA, Graziella Hanna
GARCIA, Doroti O.
MOSTARDEIRO, Marcelo
FANTI, Karina S. V. N.
Citação
MEMORIAS DO INSTITUTO OSWALDO CRUZ, v.108, n.1, p.113-115, 2013
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
This study describes a carbapenem-resistant Klebsiella pneumoniae (CRKP) outbreak that occurred from October 2008-December 2010. Polymerase chain reaction assays were performed to detect the bla(KPC) gene and molecular typing was performed using pulsed-field gel electrophoresis (PFGE). There were 33 CRKP infections; PFGE revealed five genotypes: genotype A in five (15%), B in 18 (55%), C in eight (24%) and two unique profiles. Genotype B was disseminated in all hospital units and belonged to the same clone identified in 11 different hospitals in the state of Sao Paulo. Sixteen (48%) patients died. Seven isolates (21%) were resistant to polymyxin B and 45% were resistant to tigecycline and amikacin.
Palavras-chave
carbapenem-resistant K. pneumoniae, nosocomial outbreak, polymyxin resistance
URI
https://observatorio.fm.usp.br/handle/OPI/1972
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MIP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/54
Artigos e Materiais de Revistas Científicas - ODS/03