https://observatorio.fm.usp.br/handle/OPI/1986
DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | VEZOZZO, Denise Cerqueira Paranagua | - |
dc.contributor.author | MENDES-CORREA, Maria Cassia | - |
dc.contributor.author | CUNHA-SILVA, Marlone | - |
dc.contributor.author | ALVARADO-MORA, Monica Viviana | - |
dc.contributor.author | FRANCA, Joao Italo Dias | - |
dc.contributor.author | SEBBA, Jose Luiz | - |
dc.contributor.author | NICODEMO, Antonio Carlos | - |
dc.contributor.author | OLIVEIRA, Claudia P. M. S. | - |
dc.contributor.author | CARRILHO, Flair Jose | - |
dc.date.accessioned | 2013-09-23T16:39:46Z | - |
dc.date.available | 2013-09-23T16:39:46Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, v.17, n.2, p.150-155, 2013 | - |
dc.identifier.issn | 1413-8670 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/1986 | - |
dc.description.abstract | Objectives: Progression of hepatic fibrosis is accelerated in patients co-infected with human immunodeficiency virus and hepatitis C virus compared to hepatitis C virus mono-infected patients. This study aimed to compare ultrasound features and selected clinical and biochemical variables between patients with human immunodeficiency virus/hepatitis C virus co-infection (n = 16) versus hepatitis C virus mono-infection (n = 16). Methods: Each patient underwent abdominal ultrasound, and a specific evaluation was performed in order to detect findings consistent with chronic liver disease. Characterization of spleen size, liver structural pattern, diameter of the portal, spleen, and mesenteric veins was based on classical ultrasound parameters. Propensity score was used for control of selection bias and performed using binary logistic regression to generate a score for each patient. The Fisher and Mann-Whitney tests were used to evaluate categorical variables and continuous variables, respectively. Results: On univariate analysis right hepatic lobe size was larger in human immunodeficiency virus/hepatitis C virus patients (157.06 +/- 17.56 mm) compared to hepatitis C virus mono-infected patients (134.94 +/- 16.95 mm) (p = 0.0011). The left hepatic lobe was also significantly larger in human immunodeficiency virus/hepatitis C virus patients (115.88 +/- 22.69 mm) versus hepatitis C virus mono-infected patients (95.06 +/- 24.18 mm) (p = 0.0177). Also, there was a strong correlation between hepatomegaly and co-infection (p = 0.005). Conclusion: Human immunodeficiency virus infection was the primary variable influencing liver enlargement in this population. Hepatomegaly on ultrasound was more common among cirrhotic human immunodeficiency virus/hepatitis C virus co-infected patients than among cirrhotic hepatitis C virus mono-infected patients. This aspect is very important in the management of human immunodeficiency virus/hepatitis C virus co-infected patients, because screening for hepatocellular carcinoma is necessary in this population. | - |
dc.description.sponsorship | Alves de Queiroz Family Fund | - |
dc.language.iso | eng | - |
dc.publisher | CONTEXTO | - |
dc.relation.ispartof | Brazilian Journal of Infectious Diseases | - |
dc.rights | openAccess | - |
dc.subject | Ultrasonography | - |
dc.subject | HIV/HCV co-infection | - |
dc.subject | Hepatomegaly | - |
dc.subject | Liver size | - |
dc.subject | Cirrhosis | - |
dc.subject.other | chronic hepatitis-c | - |
dc.subject.other | human-immunodeficiency-virus | - |
dc.subject.other | antiretroviral therapy | - |
dc.subject.other | liver fibrosis | - |
dc.subject.other | infected patients | - |
dc.subject.other | hcv genotype | - |
dc.subject.other | risk-factors | - |
dc.subject.other | hiv | - |
dc.subject.other | steatosis | - |
dc.subject.other | ultrasound | - |
dc.title | Strong correlation by ultrasonography of hepatomegaly and the presence of co-infection in HIV/HCV cirrhotic patients | - |
dc.type | article | - |
dc.rights.holder | Copyright CONTEXTO | - |
dc.identifier.doi | 10.1016/j.bjid.2012.09.009 | - |
dc.identifier.pmid | 23453412 | - |
dc.subject.wos | Infectious Diseases | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | CUNHA-SILVA, Marlone:Univ Sao Paulo, Sch Med, Dept Gastroenterol, BR-05403000 Sao Paulo, Brazil | - |
hcfmusp.author.external | FRANCA, Joao Italo Dias:Univ Sao Paulo, Sch Med, Dept Gastroenterol, BR-05403000 Sao Paulo, Brazil | - |
hcfmusp.description.beginpage | 150 | - |
hcfmusp.description.endpage | 155 | - |
hcfmusp.description.issue | 2 | - |
hcfmusp.description.volume | 17 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | WOS:000318743300006 | - |
hcfmusp.origem.id | 2-s2.0-84876699570 | - |
hcfmusp.origem.id | SCIELO:S1413-86702013000200006 | - |
hcfmusp.publisher.city | SALVADOR | - |
hcfmusp.publisher.country | BRAZIL | - |
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dc.description.index | MEDLINE | - |
hcfmusp.citation.scopus | 3 | - |
hcfmusp.scopus.lastupdate | 2024-04-12 | - |
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art_VEZOZZO_Strong_correlation_by_ultrasonography_of_hepatomegaly_and_the_2013.PDF | publishedVersion (English) | 526.47 kB | Adobe PDF | View/Open |
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