Organochlorine pesticides levels and associated factors in a group of blood donors in Sao Paulo, Brazil
Carregando...
Citações na Scopus
10
Tipo de produção
article
Data de publicação
2017
Título da Revista
ISSN da Revista
Título do Volume
Editora
SPRINGER
Autores
KUNO, Rbia
LEMES, Vera Regina Rossi
KUSSUMI, Tereza Atsuko
NAKANO, Viviane Emi
ROCHA, Sonia Bio
OLIVEIRA, Maria Celeste Cardeal de
KIMURA, Iracema de Albuquerque
Citação
ENVIRONMENTAL MONITORING AND ASSESSMENT, v.189, n.8, article ID 380, 9p, 2017
Resumo
The use of organochlorine pesticides (OCPs) is a worldwide public health concern given that high levels of these compounds in humans and animals can lead to serious health problems. This study aimed to evaluate the levels of 15 organochlorine pesticides in the serum of 547 blood donors in the Sao Paulo metropolitan region (SPMR) in 2009 and to investigate factors associated with higher levels of these compounds. The OCPs were determined by gas chromatography with micro electron capture detection. Multiple ordinal logistic regression models were employed to determine the factors associated with higher levels. Only beta-HCH and p,p'-DDE had a significant number of samples above the limit of quantification. Factors associated with higher levels of beta-HCH were age within 26 to 35 years (OR = 3.1 [1.05-9.09]), age within 36 to 45 years (OR = 18.27 [6.89-48.91]), and female gender (OR = 0.44 [0.24-0.82] for men). p, p'-DDE levels were associated with age within 26 to 35 years (OR = 2.65 [1.20-3.45]), age within 36 to 45 years (OR = 4.59 [2.64-7.92]), female gender (OR = 0.86 [0.43-0.94] for men), and previous work with pesticides (OR = 2.88 [1.22-6.84]). Lower levels of p, p'-DDE were associated with an income of 3 to 5 minimum wages (OR = 0.38 [0.19-0.75]) and with intake of foods from animal origin up to twice a week (OR = 0.15 [0.03-0.72]) and more than twice a week (OR = 0.10 [0.02-0.47]). The results of this study indicate that the study group was not exposed to high levels of OCPs.
Palavras-chave
DDT, beta-HCH, Serum, Blood donors, Human biomonitoring
Referências
- Almeida W. F., 1972, THESIS
- Angerer J, 2007, INT J HYG ENVIR HEAL, V210, P201, DOI 10.1016/j.ijheh.2007.01.024
- ANVISA, 2009, PROGR AN RES AGR AL
- Arrebola JP, 2012, ENVIRON INT, V38, P54, DOI 10.1016/j.envint.2011.08.006
- Arrebola JP, 2013, SCI TOTAL ENVIRON, V458, P209, DOI 10.1016/j.scitotenv.2013.04.001
- ATSDR (Agency for Toxic Substances and Disease Registry), 2002, TOX PROF DDT DDE DDD
- Bjermo H, 2013, ENVIRON INT, V51, P88, DOI 10.1016/j.envint.2012.10.010
- CARVALHO W A, 1991, Boletin de la Oficina Sanitaria Panamericana, V111, P512
- Charlier CJ, 2002, CLIN CHEM LAB MED, V40, P361, DOI 10.1515/CCLM.2002.058
- Cruz S, 2003, SCI TOTAL ENVIRON, V317, P23, DOI 10.1016/S0048-9697(03)00334-6
- Delgado Isabella Fernandes, 2002, Cad. Saúde Pública, V18, P519, DOI 10.1590/S0102-311X2002000200017
- Fernicola N. A., 1982, VET HUM TOXICOL, V24, P91
- Gasull M, 2011, ENVIRON INT, V37, P1226, DOI 10.1016/j.envint.2011.05.008
- Hanaoka T, 2002, SCI TOTAL ENVIRON, V286, P119, DOI 10.1016/S0048-9697(01)00969-X
- Hassine S. B., 2014, ENVIRON SCI POLLUT R, V21, P6303
- Health Canada, 2010, REP HUM BIOM ENV CHE
- Jakszyn P, 2009, CHEMOSPHERE, V76, P1518, DOI 10.1016/j.chemosphere.2009.05.048
- LARA W H, 1987, Revista do Instituto Adolfo Lutz, V47, P19
- Lee DH, 2006, DIABETES CARE, V29, P1638, DOI 10.2337/dc05-0543
- Lopes-Flores I, 2009, EXPOSICION LABORAL P
- Mendonca GAS, 1999, INT J CANCER, V83, P596, DOI 10.1002/(SICI)1097-0215(19991126)83:5<596::AID-IJC4>3.3.CO;2-G
- Minelli EV, 1996, B ENVIRON CONTAM TOX, V57, P691
- Mnif W, 2011, INT J ENV RES PUB HE, V8, P2265, DOI 10.3390/ijerph8062265
- Nakata H, 2002, ARCH ENVIRON CON TOX, V43, P473, DOI [10.1007/S00244-002-1254-8, 10.1007/s00244-002-1254-8]
- Oliveira-Silva JJ, 2001, REV SAUDE PUBL, V35, P130, DOI 10.1590/S0034-89102001000200005
- Paumgartten F J, 1998, Cad Saude Publica, V14 Suppl 3, P33
- Porta M, 2012, SCI TOTAL ENVIRON, V423, P151, DOI 10.1016/j.scitotenv.2012.02.001
- RADOMSKI JL, 1971, TOXICOL APPL PHARM, V20, P175, DOI 10.1016/0041-008X(71)90043-3
- Rojas-Squella X, 2013, CHEMOSPHERE, V91, P733, DOI 10.1016/j.chemosphere.2013.02.026
- Sala M, 1999, OCCUP ENVIRON MED, V56, P152
- Stellman SD, 1998, CANCER EPIDEM BIOMAR, V7, P489
- Turnbull A., 1996, ISS ENV SCI TECHNOL, V6, P113
- UNEP, 2006, 217ADD4 UNEP UNEPPOP
- USEPA, 1980, 68022474 USEPA
- USEPA, 2015, INT RISK INF SYST
- USEPA, 2003, 822R03001 USEPA
- Wang HS, 2013, ENVIRON INT, V54, P18, DOI 10.1016/j.envint.2013.01.003
- WHO, 1997, ENV HLTH CRIT
- Yang RQ, 2010, ENVIRON POLLUT, V158, P2310, DOI 10.1016/j.envpol.2010.02.004
- Zhou RB, 2006, J HAZARD MATER, V137, P68, DOI 10.1016/j.jhazmat.2006.02.005